-
1
-
-
0024449217
-
Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus
-
1. Wittbrodt, J., Adam, D., Malitschek, B., Mäueler, W., Raulf, F., Telling, A., Robertson, S.M. & Schartl, M. (1989) Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus. Nature 341, 415-421.
-
(1989)
Nature
, vol.341
, pp. 415-421
-
-
Wittbrodt, J.1
Adam, D.2
Malitschek, B.3
Mäueler, W.4
Raulf, F.5
Telling, A.6
Robertson, S.M.7
Schartl, M.8
-
2
-
-
0026657858
-
The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma
-
2. Wittbrodt, J., Lammers, R., Malitschek, B., Ullrich, A. & Schartl, M. (1992) The Xmrk receptor tyrosine kinase is activated in Xiphophorus malignant melanoma. EMBO J. 11, 4239-4246.
-
(1992)
EMBO J.
, vol.11
, pp. 4239-4246
-
-
Wittbrodt, J.1
Lammers, R.2
Malitschek, B.3
Ullrich, A.4
Schartl, M.5
-
3
-
-
0028272397
-
Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene
-
3. Winkler, C., Wittbrodt, J., Lammers, R., Ullrich, A. & Schartl, M. (1994) Ligand-dependent tumor induction in medakafish embryos by a Xmrk receptor tyrosine kinase transgene. Oncogene 9, 1517-1525.
-
(1994)
Oncogene
, vol.9
, pp. 1517-1525
-
-
Winkler, C.1
Wittbrodt, J.2
Lammers, R.3
Ullrich, A.4
Schartl, M.5
-
4
-
-
0031779657
-
Receptor tyrosine kinase Xmrk mediates proliferation in Xiphphorus melanoma cells
-
4. Wellbrock, C., Fischer, P. & Schartl, M. (1998) Receptor tyrosine kinase Xmrk mediates proliferation in Xiphphorus melanoma cells. Int J. Cancer 76, 437-442.
-
(1998)
Int J. Cancer
, vol.76
, pp. 437-442
-
-
Wellbrock, C.1
Fischer, P.2
Schartl, M.3
-
5
-
-
0019382251
-
Establishment of a cell line from the platyfish-swordtail hybrid melanoma
-
5. Wakamatsu, Y. (1981) Establishment of a cell line from the platyfish-swordtail hybrid melanoma. Cancer Res. 41, 679-680.
-
(1981)
Cancer Res.
, vol.41
, pp. 679-680
-
-
Wakamatsu, Y.1
-
6
-
-
0028276959
-
Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand
-
6. Malitschek, B., Wittbrodt, J., Fischer, P., Lammers, R., Ullrich, A. & Schartl, M. (1994) Autocrine stimulation of the Xmrk receptor tyrosine kinase in Xiphophorus melanoma cells and identification of a source for the physiological ligand. J. Biol. Chem. 14, 10423-10430.
-
(1994)
J. Biol. Chem.
, vol.14
, pp. 10423-10430
-
-
Malitschek, B.1
Wittbrodt, J.2
Fischer, P.3
Lammers, R.4
Ullrich, A.5
Schartl, M.6
-
7
-
-
0033557478
-
Multiple binding sites in the growth factor receptor Xmrk mediate binding to p59fyn, GRB2 and Shc
-
7. Wellbrock, C. & Schartl, M. (1999) Multiple binding sites in the growth factor receptor Xmrk mediate binding to p59fyn, GRB2 and Shc. Eur. J. Biochem. 260, 275-283.
-
(1999)
Eur. J. Biochem.
, vol.260
, pp. 275-283
-
-
Wellbrock, C.1
Schartl, M.2
-
8
-
-
0033568180
-
PI3-kinase is involved in mitogenic signaling by the oncogenic receptor tyrosine kinase Xmrk in fish melanoma
-
8. Wellbrock, C., Fischer, P. & Schartl, M. (1999) PI3-kinase is involved in mitogenic signaling by the oncogenic receptor tyrosine kinase Xmrk in fish melanoma. Exp. Cell Res. 251, 340-349.
-
(1999)
Exp. Cell Res.
, vol.251
, pp. 340-349
-
-
Wellbrock, C.1
Fischer, P.2
Schartl, M.3
-
9
-
-
0031854013
-
Downstream of Phosphatidylinositol -3 kinase, a multifunctional signaling molecule, and its regulation in cell responses
-
9. Fukui, Y., Ihara, S. & Nagata, S. (1998) Downstream of Phosphatidylinositol -3 kinase, a multifunctional signaling molecule, and its regulation in cell responses. J. Biochem. 124, 1-7.
-
(1998)
J. Biochem.
, vol.124
, pp. 1-7
-
-
Fukui, Y.1
Ihara, S.2
Nagata, S.3
-
10
-
-
0031203965
-
Differential association of phosphatidylinositol 3-kinase with insulin receptor substrate (IRS)-1 and IRS-2 in human thymocytes in response to IL-7
-
10. Sharfe, N. & Roifman, C.M. (1997) Differential association of phosphatidylinositol 3-kinase with insulin receptor substrate (IRS)-1 and IRS-2 in human thymocytes in response to IL-7. J. Immunol. 159, 1107-1114.
-
(1997)
J. Immunol.
, vol.159
, pp. 1107-1114
-
-
Sharfe, N.1
Roifman, C.M.2
-
11
-
-
0025172811
-
Association between the PDGF receptor and members of the src family of tyrosine kinases
-
11. Kypta, R.M., Goldberg, Y., Ulug, E.T. & Courtneidge, S.A. (1990) Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell 62, 481-492.
-
(1990)
Cell
, vol.62
, pp. 481-492
-
-
Kypta, R.M.1
Goldberg, Y.2
Ulug, E.T.3
Courtneidge, S.A.4
-
12
-
-
0027275832
-
Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells
-
12. Prasad, K.V.S., Janssen, O., Kapeller, R., Raab, M., Cantley, L.C. & Rudd, C.E. (1993) Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells. Proc. Natl Acad. Sci. USA 90, 7366-7370.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 7366-7370
-
-
Prasad, K.V.S.1
Janssen, O.2
Kapeller, R.3
Raab, M.4
Cantley, L.C.5
Rudd, C.E.6
-
13
-
-
0028198388
-
Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit
-
13. Pleiman, C.M., Hertz, W.M. & Cambier, J.C. (1994) Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit. Science 263, 1609-1612.
-
(1994)
Science
, vol.263
, pp. 1609-1612
-
-
Pleiman, C.M.1
Hertz, W.M.2
Cambier, J.C.3
-
14
-
-
0028926540
-
Platyfish and swordtails: A genetic system for the analysis of molecular mechanisms in tumor formation
-
14. Schartl, M. (1995) Platyfish and swordtails: a genetic system for the analysis of molecular mechanisms in tumor formation. Trends Genet. 11, 185-189.
-
(1995)
Trends Genet.
, vol.11
, pp. 185-189
-
-
Schartl, M.1
-
15
-
-
0027953284
-
PI3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity
-
15. Dhand, R., Hiles, I., Panayotou, G., Roche, S., Fry, M.J., Gout, I., Totty, N.F., Truong, O., Vicendo, P., Yonezawa, K., Kasuga, M., Courtneidge, S.A. & Waterfield, M.D. (1994) PI3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J. 13, 522-533.
-
(1994)
EMBO J.
, vol.13
, pp. 522-533
-
-
Dhand, R.1
Hiles, I.2
Panayotou, G.3
Roche, S.4
Fry, M.J.5
Gout, I.6
Totty, N.F.7
Truong, O.8
Vicendo, P.9
Yonezawa, K.10
Kasuga, M.11
Courtneidge, S.A.12
Waterfield, M.D.13
-
16
-
-
0026567491
-
SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: Identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma
-
16. Rotin, D., Margolis, B., Mohammadi, M., Daly, R.J., Daum, G., Li, N., Fischer, E., Burgess, W., Ullrich, A. & Schlessinger, J. (1992) SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma. EMBO J. 11, 559-567.
-
(1992)
EMBO J.
, vol.11
, pp. 559-567
-
-
Rotin, D.1
Margolis, B.2
Mohammadi, M.3
Daly, R.J.4
Daum, G.5
Li, N.6
Fischer, E.7
Burgess, W.8
Ullrich, A.9
Schlessinger, J.10
-
17
-
-
0029041314
-
Association between the melanoma-inducing receptor tyrosine kinase Xmrk and src family tyrosine kinases in Xiphophorus
-
17. Wellbrock, C., Lammers, R., Ullrich, A. & Schartl, M. (1995) Association between the melanoma-inducing receptor tyrosine kinase Xmrk and src family tyrosine kinases in Xiphophorus. Oncogene 10, 2135-2143.
-
(1995)
Oncogene
, vol.10
, pp. 2135-2143
-
-
Wellbrock, C.1
Lammers, R.2
Ullrich, A.3
Schartl, M.4
-
18
-
-
0024467516
-
The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein
-
18. Langdon, W.Y., Hyland, C.D., Grumont, R.J. & Morse, H.C. III (1989) The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein. J. Virol. 63, 5420-5424.
-
(1989)
J. Virol.
, vol.63
, pp. 5420-5424
-
-
Langdon, W.Y.1
Hyland, C.D.2
Grumont, R.J.3
Morse H.C. III4
-
19
-
-
0029671073
-
p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase
-
19. Panchamoorthy, G., Fukazawa, T., Miyake, S., Soltoff, S., Reedquist, K., Druker, B., Shoelson, S., Cantley, L. & Band, H. (1996) p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase. J. Biol. Chem. 271, 3187-3194.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3187-3194
-
-
Panchamoorthy, G.1
Fukazawa, T.2
Miyake, S.3
Soltoff, S.4
Reedquist, K.5
Druker, B.6
Shoelson, S.7
Cantley, L.8
Band, H.9
-
20
-
-
0031033308
-
Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase
-
20. Anderson, S.M., Burton, E.A. & Koch, B.L. (1997) Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase. J. Biol. Chem. 272, 739-745.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 739-745
-
-
Anderson, S.M.1
Burton, E.A.2
Koch, B.L.3
-
21
-
-
0029671427
-
p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells
-
21. Soltoff, S.P. & Cantley, L.C. (1996) p120cbl is a cytosolic adapter protein that associates with phosphoinositide 3-kinase in response to epidermal growth factor in PC12 and other cells. J. Biol. Chem. 271, 563-567.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 563-567
-
-
Soltoff, S.P.1
Cantley, L.C.2
-
22
-
-
17544365654
-
Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins
-
22. Fukazawa, T., Miyake, S., Band, V. & Band, H. (1996) Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins. J. Biol. Chem. 271, 14554-14559.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14554-14559
-
-
Fukazawa, T.1
Miyake, S.2
Band, V.3
Band, H.4
-
23
-
-
0027300619
-
The when and how of Src regulation
-
23. Cooper, J.A. & Howell, B. (1993) The when and how of Src regulation. Cell 73, 1051-1054.
-
(1993)
Cell
, vol.73
, pp. 1051-1054
-
-
Cooper, J.A.1
Howell, B.2
-
24
-
-
0030072570
-
Vertebrate non-receptor protein-tyrosine kinase families
-
24. Neet, K. & Hunter, T. (1996) Vertebrate non-receptor protein-tyrosine kinase families. Genes Cells 1, 147-169.
-
(1996)
Genes Cells
, vol.1
, pp. 147-169
-
-
Neet, K.1
Hunter, T.2
-
25
-
-
0027361489
-
Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of Xiphophorus
-
25. Mäueler, W., Schartl, A. & Schartl, M. (1993) Different expression patterns of oncogenes and proto-oncogenes in hereditary and carcinogen-induced tumors of Xiphophorus. Int. J. Cancer 55, 288-296.
-
(1993)
Int. J. Cancer
, vol.55
, pp. 288-296
-
-
Mäueler, W.1
Schartl, A.2
Schartl, M.3
-
26
-
-
0026083794
-
Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus
-
26. Adam, D., Mäueler, W. & Schartl, M. (1991) Transcriptional activation of the melanoma inducing Xmrk oncogene in Xiphophorus. Oncogene 6, 73-80.
-
(1991)
Oncogene
, vol.6
, pp. 73-80
-
-
Adam, D.1
Mäueler, W.2
Schartl, M.3
-
27
-
-
0030000234
-
Differences in binding of PI 3-kinase to the src-homology domains 2 and 3 of p56 lck and p59 fyn tyrosine kinases
-
27. Susa, M., Rohner, D. & Bichsel, S. (1996) Differences in binding of PI 3-kinase to the src-homology domains 2 and 3 of p56 lck and p59 fyn tyrosine kinases. Biochem. Biophys. Res. Commun. 220, 729-734.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.220
, pp. 729-734
-
-
Susa, M.1
Rohner, D.2
Bichsel, S.3
-
28
-
-
0029051695
-
The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase
-
28. Fukazawa, T., Reedquist, K.A., Trub, T., Soltoff, S., Panchamoorthy, G., Druker, B., Cantley, L., Shoelson, S.E. & Band, H. (1995) The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase. J. Biol. Chem. 270, 19141-19150.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19141-19150
-
-
Fukazawa, T.1
Reedquist, K.A.2
Trub, T.3
Soltoff, S.4
Panchamoorthy, G.5
Druker, B.6
Cantley, L.7
Shoelson, S.E.8
Band, H.9
-
29
-
-
0033593322
-
Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase
-
29. Hunter, S., Burton, E.A., Wu, S.C. & Anderson, S.M. (1999) Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase. J. Biol. Chem. 274, 2097-2106.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2097-2106
-
-
Hunter, S.1
Burton, E.A.2
Wu, S.C.3
Anderson, S.M.4
-
30
-
-
0029094649
-
Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation
-
30. Galisteo, M.L., Dikic, I., Batzer, A.C., Langdon, W.Y. & Schlessinger, J. (1995) Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. J. Biol. Chem. 270, 20242-20245.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 20242-20245
-
-
Galisteo, M.L.1
Dikic, I.2
Batzer, A.C.3
Langdon, W.Y.4
Schlessinger, J.5
-
31
-
-
0027403027
-
SH2 domains recognize specific phosphopeptide sequences
-
31. Songyang, Z., Shoelson, S.E., Chaudhuri, M., Gish, G., Pawson, T., Haser, W.G., King, F., Roberts, T., Ratnofsky, S., Lechleider, R.J., Neel, B.C., Birge, R.B., Fajardo, J.E., Chou, M.M., Hanafusa, H., Schaffhausen, B. & Cantley, L.C. (1993) SH2 domains recognize specific phosphopeptide sequences. Cell 72, 767-778.
-
(1993)
Cell
, vol.72
, pp. 767-778
-
-
Songyang, Z.1
Shoelson, S.E.2
Chaudhuri, M.3
Gish, G.4
Pawson, T.5
Haser, W.G.6
King, F.7
Roberts, T.8
Ratnofsky, S.9
Lechleider, R.J.10
Neel, B.C.11
Birge, R.B.12
Fajardo, J.E.13
Chou, M.M.14
Hanafusa, H.15
Schaffhausen, B.16
Cantley, L.C.17
-
32
-
-
0028302018
-
ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
-
32. Soltoff, S.P., Carraway, K.L., III, Prigent, S.A., Gullick, W.G. & Cantley, L.C. (1994) ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol. Cell. Biol. 14, 3550-3558.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 3550-3558
-
-
Soltoff, S.P.1
Carraway K.L. III2
Prigent, S.A.3
Gullick, W.G.4
Cantley, L.C.5
-
33
-
-
0027436140
-
Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: The p56lck SH3 domain binds lo PI 3-kinase but not PI 4-kinase
-
33. Prasad, K.V., Kapeller, R., Janssen, O., Repke, H., Duke-Cohan, J.S., Cantley, L.C. & Rudd, C.E. (1993) Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds lo PI 3-kinase but not PI 4-kinase. Mol. Cell. Biol. 13, 7708-7717.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7708-7717
-
-
Prasad, K.V.1
Kapeller, R.2
Janssen, O.3
Repke, H.4
Duke-Cohan, J.S.5
Cantley, L.C.6
Rudd, C.E.7
-
34
-
-
0027333338
-
The SH3 domain of p56lck is involved in binding to phosphatidylinosilol 3′-kinase from T lymphocytes
-
34. Vogel, L.B. & Fujita, D.J. (1993) The SH3 domain of p56lck is involved in binding to phosphatidylinosilol 3′-kinase from T lymphocytes. Mol. Cell. Biol. 13, 7408-7417.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7408-7417
-
-
Vogel, L.B.1
Fujita, D.J.2
-
35
-
-
0027214258
-
The v-Src SH3 domain binds phosphatidylinositol 3′-kinase
-
35. Liu, X., Marengere, L.M., Koch, A.C. & Pawson, T. (1993) The v-Src SH3 domain binds phosphatidylinositol 3′-kinase. Mol. Cell. Biol. 13, 5225-5232.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 5225-5232
-
-
Liu, X.1
Marengere, L.M.2
Koch, A.C.3
Pawson, T.4
-
36
-
-
0028123778
-
Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase
-
36. Kapeller, R., Prasad, K.V.S., Janssen, O., Hou, W., Schaffhausen, B.S., Rudd, C.E. & Cantley, L.C. (1994) Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. J. Biol. Chem. 269, 1927-1933.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1927-1933
-
-
Kapeller, R.1
Prasad, K.V.S.2
Janssen, O.3
Hou, W.4
Schaffhausen, B.S.5
Rudd, C.E.6
Cantley, L.C.7
-
37
-
-
0016954553
-
Genetic control of cell differentiation in platyfish-swordtail melanomas
-
37. Vielkind, U. (1976) Genetic control of cell differentiation in platyfish-swordtail melanomas. J. Exp. Zool. 196, 197-204.
-
(1976)
J. Exp. Zool.
, vol.196
, pp. 197-204
-
-
Vielkind, U.1
-
38
-
-
0029775645
-
Inhibition of the phosphatidylinositol 3-kinase/p70 (S6)-kinase pathway induces B16 melanoma cell differentiation
-
38. Buscà, R., Bertolotto, C. & Ortonne and Ballotti, R. (1996) Inhibition of the phosphatidylinositol 3-kinase/p70 (S6)-kinase pathway induces B16 melanoma cell differentiation. J. Biol. Chem. 271, 31824-31830.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31824-31830
-
-
Buscà, R.1
Bertolotto, C.2
Ortonne3
Ballotti, R.4
-
39
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
39. Alessi, D.R., Andjelkovic, M., Caudwell, B., Cron, P., Morrice, N., Cohen, P. & Hemmings, B.A. (1996) Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15, 6541-6551.
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
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