Characterization of CYP2C19 and CYP2C9 from human liver: Respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations

Archives of Biochemistry and Biophysics

Volumn 353, Issue 1, 1998, Pages 16-28

  Lasker, Jerome M ^a   Wester, Michael R ^b,c   Aramsombatdee, Eileen ^a   Raucy, Judy L ^c  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c AGOURON PHARMACEUTICALS INC   (United States)

Author keywords

CYP2C19; CYP2C8; CYP2C9; Human liver microsomes; Omeprazole; S mephenytoin; Tolbutamide

Indexed keywords

MEPHENYTOIN; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; TOLBUTAMIDE; WARFARIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATALYSIS; CATALYST; CHROMATOGRAPHY; DRUG METABOLISM; ENZYME POLYMORPHISM; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; LIVER MICROSOME; OXIDATION; PRIORITY JOURNAL; YEAST;

EID: 0031856787     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1998.0615     Document Type: Article

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