Death associated protein kinase as a potential therapeutic target

Expert Opinion on Therapeutic Targets

Volumn 6, Issue 4, 2002, Pages 497-506

  Schumacher, Andrew M ^a   Velentza, Anastasia V ^a   Watterson, D Martin ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Apoptosis; Calmodulin; Cancer; Death associated protein kinase; Ischaemia; Neurodegeneration; Protein kinase inhibitor; Stroke; Tumour suppression

Indexed keywords

5 (2,6 DICHLOROPHENYL) 2 (2,4 DIFLUOROPHENYLTHIO)PYRIMIDO[1,6 B]PYRIDAZIN 6 ONE; 5 (4 PYRIDINYL) 4 (4 FLUOROPHENYL) 1 (4 PIPERIDINYL)IMIDAZOLE; 5 AZA 2' DEOXYCYTIDINE; ADENOSINE TRIPHOSPHATE; ANTIPSORIASIS AGENT; ANTIRHEUMATIC AGENT; CALMODULIN; CALMODULIN INHIBITOR; CERAMIDE; FAS ANTIGEN; GAMMA INTERFERON; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE INHIBITOR; PROTEIN P53; PROTEIN P55; PROTEIN SERINE THREONINE KINASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; VX 746;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN NERVE CELL; CANCER INHIBITION; CATALYSIS; CENTRAL NERVOUS SYSTEM; CEREBROVASCULAR ACCIDENT; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOUSE; NERVE CELL LESION; NERVE DEGENERATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; PSORIASIS; RAT; RECEPTOR DOWN REGULATION; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN; CENTRAL NERVOUS SYSTEM AGENTS; CERAMIDES; DOGS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENZYME INDUCTION; GENES, TUMOR SUPPRESSOR; HUMANS; MICE; MODELS, ANIMAL; MODELS, MOLECULAR; NEOPLASM PROTEINS; NEOPLASMS; NERVE DEGENERATION; NERVE TISSUE PROTEINS; PROTEIN CONFORMATION; PROTEIN KINASE INHIBITORS;

EID: 0036045731     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728222.6.4.497     Document Type: Review

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