A protein kinase associated with apoptosis and tumor suppression: Structure, activity, and discovery of peptide substrates

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 38956-38965

  Velentza, Anastasia V ^a   Schumacher, Andrew M ^a   Weiss, Curtis ^a   Egli, Martin ^b   Watterson, D Martin ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BRAIN; CELLS; DISEASES; DNA; GENETIC ENGINEERING; PURIFICATION; TUMORS;

HOMOLOGY MODELS;

ENZYMES;

PROTEIN KINASE; APOPTOSIS REGULATORY PROTEIN; COMPLEMENTARY DNA; DEATH ASSOCIATED PROTEIN KINASE; PEPTIDE; PEPTIDE LIBRARY; PROTEIN KINASE (CALCIUM,CALMODULIN); RECOMBINANT PROTEIN; TUMOR SUPPRESSOR PROTEIN;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CATALYSIS; CHEMICAL PARAMETERS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE; GENE SEQUENCE; GENETIC SCREENING; GENOME; HUMAN; MICHAELIS CONSTANT; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PHYSICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEOMICS; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; BRAIN; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; KINETICS; METABOLISM; MOLECULAR GENETICS; OPEN READING FRAME; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BINDING SITES; BLOTTING, WESTERN; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CATALYSIS; CATALYTIC DOMAIN; CATTLE; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTAGENESIS, SITE-DIRECTED; OPEN READING FRAMES; PEPTIDE LIBRARY; PEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TUMOR SUPPRESSOR PROTEINS;

EID: 0035914415     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104273200     Document Type: Article

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