-
2
-
-
0036195261
-
Stroke prevention therapy beyond antithrombotics: Unifying mechanisms in ischemic stroke pathogenesis and implications for therapy
-
Gorelick P.B. Stroke prevention therapy beyond antithrombotics: unifying mechanisms in ischemic stroke pathogenesis and implications for therapy. Stroke. 33:2002;862-875.
-
(2002)
Stroke
, vol.33
, pp. 862-875
-
-
Gorelick, P.B.1
-
3
-
-
0344065373
-
Recommendations for standards regarding preclinical neuroprotective and restorative drug development
-
Recommendations for standards regarding preclinical neuroprotective and restorative drug development. Stroke. 30:1999;2752-2758.
-
(1999)
Stroke
, vol.30
, pp. 2752-2758
-
-
-
4
-
-
0019366919
-
The influence of immaturity on hypoxic-ischemic brain damage in the rat
-
Rice J.E. III, Vannucci R.C., Brierley J.B. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann. Neurol. 9:1981;131-141.
-
(1981)
Ann. Neurol.
, vol.9
, pp. 131-141
-
-
Rice III, J.E.1
Vannucci, R.C.2
Brierley, J.B.3
-
5
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
Chan P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. 21:2001;2-14.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 2-14
-
-
Chan, P.H.1
-
6
-
-
0023137252
-
Ionic dependence of glutamate neurotoxicity
-
Choi D.W. Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7:1987;369-379.
-
(1987)
J. Neurosci.
, vol.7
, pp. 369-379
-
-
Choi, D.W.1
-
7
-
-
0028799654
-
Calcium: Still center-stage in hypoxic-ischemic neuronal death
-
Choi D. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18:1995;58-60.
-
(1995)
Trends Neurosci.
, vol.18
, pp. 58-60
-
-
Choi, D.1
-
8
-
-
0031953601
-
Calcium in ischemic cell death
-
Kristián T., Siesjö B.K. Calcium in ischemic cell death. Stroke. 29:1998;705-718.
-
(1998)
Stroke
, vol.29
, pp. 705-718
-
-
Kristián, T.1
Siesjö, B.K.2
-
9
-
-
0017356990
-
Calcium modulation in brain extracellular microenviroment demonstrated with ion-selective micropipette
-
Nicholson C., Bruggencate G.T., Steinberg R., Stockle H. Calcium modulation in brain extracellular microenviroment demonstrated with ion-selective micropipette. Proc. Natl. Acad. Sci. U. S. A. 74:1977;1287-1290.
-
(1977)
Proc. Natl. Acad. Sci. U. S. A.
, vol.74
, pp. 1287-1290
-
-
Nicholson, C.1
Bruggencate, G.T.2
Steinberg, R.3
Stockle, H.4
-
10
-
-
0033485672
-
Developmental changes in distribution of death-associated protein kinase mRNAs
-
Yamamoto M., Takahashi H., Nakamura T., Hioki T., Nagayama S., Ooashi N., Sun X., Ishii T., Kudo Y., Nakajima-Iijima S., Kimchi A., Uchino S. Developmental changes in distribution of death-associated protein kinase mRNAs. J. Neurosci. Res. 58:1999;674-683.
-
(1999)
J. Neurosci. Res.
, vol.58
, pp. 674-683
-
-
Yamamoto, M.1
Takahashi, H.2
Nakamura, T.3
Hioki, T.4
Nagayama, S.5
Ooashi, N.6
Sun, X.7
Ishii, T.8
Kudo, Y.9
Nakajima-Iijima, S.10
Kimchi, A.11
Uchino, S.12
-
11
-
-
0025253199
-
Naturally occurring cell death in the subicular complex and hippocampus in the rat during development
-
Ferrer I., Serrano T., Soriano E. Naturally occurring cell death in the subicular complex and hippocampus in the rat during development. Neurosci. Res. 8:1990;60-66.
-
(1990)
Neurosci. Res.
, vol.8
, pp. 60-66
-
-
Ferrer, I.1
Serrano, T.2
Soriano, E.3
-
12
-
-
0026071151
-
Naturally occurring cell death in the developing dentate gyrus of the rat
-
Gould E., Woolley C.S., McEwen B.S. Naturally occurring cell death in the developing dentate gyrus of the rat. J. Comp. Neurol. 304:1991;408-418.
-
(1991)
J. Comp. Neurol.
, vol.304
, pp. 408-418
-
-
Gould, E.1
Woolley, C.S.2
McEwen, B.S.3
-
13
-
-
0027373764
-
Programmed cell death and the control of cell survival: Lessons from the nervous system
-
Raff M.C., Barres B.A., Burne J.F., Coles H.S., Ishizake Y., Jacobson M.D. Programmed cell death and the control of cell survival: lessons from the nervous system. Science. 262:1993;695-700.
-
(1993)
Science
, vol.262
, pp. 695-700
-
-
Raff, M.C.1
Barres, B.A.2
Burne, J.F.3
Coles, H.S.4
Ishizake, Y.5
Jacobson, M.D.6
-
15
-
-
0037127269
-
Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons
-
Pelled D., Raveh T., Riebeling C., Fridkin M., Berissi H., Futerman A.H., Kimchi A. Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons. J. Biol. Chem. 277:2002;1957-1961.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1957-1961
-
-
Pelled, D.1
Raveh, T.2
Riebeling, C.3
Fridkin, M.4
Berissi, H.5
Futerman, A.H.6
Kimchi, A.7
-
17
-
-
0033549557
-
DAP-kinase participates in TNF-α- and Fas-induced apoptosis and its function requires the death domain
-
Cohen O., Inbal B., Kissel J.L., Raveh T., Berissi H., Spivak-Kroizaman T., Feinstein E., Kimchi A. DAP-kinase participates in TNF-α- and Fas-induced apoptosis and its function requires the death domain. J. Cell Biol. 146:1999;141-148.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 141-148
-
-
Cohen, O.1
Inbal, B.2
Kissel, J.L.3
Raveh, T.4
Berissi, H.5
Spivak-Kroizaman, T.6
Feinstein, E.7
Kimchi, A.8
-
18
-
-
0034991340
-
Neurobiology of hypoxic-ischemic injury in the developing brain
-
Johnston M., Trescher W., Ishida A., Nakajima W. Neurobiology of hypoxic-ischemic injury in the developing brain. Pediatr. Res. 49:2001;735-741.
-
(2001)
Pediatr. Res.
, vol.49
, pp. 735-741
-
-
Johnston, M.1
Trescher, W.2
Ishida, A.3
Nakajima, W.4
-
19
-
-
0025734533
-
At what age is the developing cerebral cortex of the rat comparable to that of the full-term human baby?
-
Romijn H.J., Hofman M.A., Gramsbergen A. At what age is the developing cerebral cortex of the rat comparable to that of the full-term human baby? Early Hum. Dev. 26:1991;61-67.
-
(1991)
Early Hum. Dev.
, vol.26
, pp. 61-67
-
-
Romijn, H.J.1
Hofman, M.A.2
Gramsbergen, A.3
-
20
-
-
0033512004
-
Inflammatory mediators and stroke: New opportunities for novel therapeutics
-
Barone F.C., Feurerstein G.Z. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 19:1999;819-834.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 819-834
-
-
Barone, F.C.1
Feurerstein, G.Z.2
-
21
-
-
0002445427
-
Anoxic-ischemic encephalopathy in rats
-
Levine S. Anoxic-ischemic encephalopathy in rats. Am. J. Pathol. 36:1960;1-17.
-
(1960)
Am. J. Pathol.
, vol.36
, pp. 1-17
-
-
Levine, S.1
-
22
-
-
0033389206
-
Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning
-
Gidday J.M., Shah A.R., Maceren R.G., Wang Q., Pelligrino D.A., Holtzman D.M., Park T.S. Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning. J. Cereb. Blood Flow Metab. 19:1999;331-340.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 331-340
-
-
Gidday, J.M.1
Shah, A.R.2
MacEren, R.G.3
Wang, Q.4
Pelligrino, D.A.5
Holtzman, D.M.6
Park, T.S.7
-
23
-
-
0031868459
-
Hypoxic preconditioning and hypoxic-ischemic brain damage in the immature rat: Pathologic and metabolic correlates
-
Vannucci R.C., Towfighi J., Vannucci S.J. Hypoxic preconditioning and hypoxic-ischemic brain damage in the immature rat: pathologic and metabolic correlates. J. Neurochem. 71:1998;1215-1220.
-
(1998)
J. Neurochem.
, vol.71
, pp. 1215-1220
-
-
Vannucci, R.C.1
Towfighi, J.2
Vannucci, S.J.3
-
24
-
-
0028221633
-
Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat
-
Gidday J.M., Fitzgibbons J.C., Shah A.R., Park T.S. Neuroprotection from ischemic brain injury by hypoxic preconditioning in the neonatal rat. Neurosci. Lett. 168:1994;221-224.
-
(1994)
Neurosci. Lett.
, vol.168
, pp. 221-224
-
-
Gidday, J.M.1
Fitzgibbons, J.C.2
Shah, A.R.3
Park, T.S.4
-
25
-
-
0029143389
-
Reduction in cerebral ischemic injury in the newborn rat by potentiation of endogenous adenosine
-
Gidday J.M., Fitzgibbons J.C., Shah A.R., Kraujalis M.J., Park T.S. Reduction in cerebral ischemic injury in the newborn rat by potentiation of endogenous adenosine. Pediatr. Res. 38:1995;306-311.
-
(1995)
Pediatr. Res.
, vol.38
, pp. 306-311
-
-
Gidday, J.M.1
Fitzgibbons, J.C.2
Shah, A.R.3
Kraujalis, M.J.4
Park, T.S.5
-
26
-
-
0034714392
-
Fluoro-Jade B: A high affinity fluorescent marker for the localization of neuronal degeneration
-
Schmued L.C., Hopkins K.J. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 874:2000;123-130.
-
(2000)
Brain Res.
, vol.874
, pp. 123-130
-
-
Schmued, L.C.1
Hopkins, K.J.2
-
27
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501.
-
(1992)
J. Cell Biol.
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
28
-
-
0345704610
-
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
-
Greene L.A., Tischler A.S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. U. S. A. 73:1976;2424-2428.
-
(1976)
Proc. Natl. Acad. Sci. U. S. A.
, vol.73
, pp. 2424-2428
-
-
Greene, L.A.1
Tischler, A.S.2
-
29
-
-
0028784610
-
Multiple gene products are produced from a novel protein kinase transcription region
-
Watterson D.M., Collinge M., Lukas T.J., Van Eldik L.J., Birukov K.G., Stepanova O.V., Shirinsky V.P. Multiple gene products are produced from a novel protein kinase transcription region. FEBS Lett. 373:1995;217-220.
-
(1995)
FEBS Lett.
, vol.373
, pp. 217-220
-
-
Watterson, D.M.1
Collinge, M.2
Lukas, T.J.3
Van Eldik, L.J.4
Birukov, K.G.5
Stepanova, O.V.6
Shirinsky, V.P.7
-
30
-
-
0242460972
-
Engineering of site-directed antisera against vertebrate calmodulin by using synthetic peptide immunogens containing an immunoreactive site
-
Van Eldik L.J., Fok K.F., Erickson B.W., Watterson D.M. Engineering of site-directed antisera against vertebrate calmodulin by using synthetic peptide immunogens containing an immunoreactive site. Proc. Natl. Acad. Sci. U. S. A. 80:1983;6775-6779.
-
(1983)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 6775-6779
-
-
Van Eldik, L.J.1
Fok, K.F.2
Erickson, B.W.3
Watterson, D.M.4
-
31
-
-
0035914415
-
A protein kinase associated with apoptosis and tumor suppression: Structure, activity, and discovery of peptide substrates
-
Velentza A.V., Schumacher A.M., Weiss C., Egli M., Watterson D.M. A protein kinase associated with apoptosis and tumor suppression: structure, activity, and discovery of peptide substrates. J. Biol. Chem. 276:2001;38956-38965.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38956-38965
-
-
Velentza, A.V.1
Schumacher, A.M.2
Weiss, C.3
Egli, M.4
Watterson, D.M.5
-
32
-
-
0037204008
-
Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic derivative antineuroinflammatory compound
-
Mirzoeva S., Sawkar A., Zasadzki M., Guo L., Velentza A.V., Dunlap V., Bourguignon J.-J., Ramstrom H., Haiech J., Van Eldik L.J., Watterson D.M. Discovery of a 3-amino-6-phenyl-pyridazine derivative as a new synthetic derivative antineuroinflammatory compound. J. Med. Chem. 45:2002;563-566.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 563-566
-
-
Mirzoeva, S.1
Sawkar, A.2
Zasadzki, M.3
Guo, L.4
Velentza, A.V.5
Dunlap, V.6
Bourguignon, J.-J.7
Ramstrom, H.8
Haiech, J.9
Van Eldik, L.J.10
Watterson, D.M.11
-
33
-
-
0034810794
-
Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression
-
Tereshko V., Teplova M., Brunzelle J., Watterson D.M., Egli M. Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression. Nat. Struct. Biol. 8:2001;899-907.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 899-907
-
-
Tereshko, V.1
Teplova, M.2
Brunzelle, J.3
Watterson, D.M.4
Egli, M.5
-
34
-
-
0030876019
-
Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain
-
Bergeron M., Ferriero D.M., Vreman H.J., Stevenson D.K., Sharp F.R. Hypoxia-ischemia, but not hypoxia alone, induces the expression of heme oxygenase-1 (HSP32) in newborn rat brain. J. Cereb. Blood Flow Metab. 17:1997;647-658.
-
(1997)
J. Cereb. Blood Flow Metab.
, vol.17
, pp. 647-658
-
-
Bergeron, M.1
Ferriero, D.M.2
Vreman, H.J.3
Stevenson, D.K.4
Sharp, F.R.5
-
35
-
-
0028006381
-
Effect of unilateral perinatal hypoxic-ischemic brain damage on the gross development of opposite cerebral hemisphere
-
Towfighi J., Housman C., Vannucci R.C., Heitjan D.F. Effect of unilateral perinatal hypoxic-ischemic brain damage on the gross development of opposite cerebral hemisphere. Biol. Neonate. 65:1994;108-118.
-
(1994)
Biol. Neonate
, vol.65
, pp. 108-118
-
-
Towfighi, J.1
Housman, C.2
Vannucci, R.C.3
Heitjan, D.F.4
-
37
-
-
0003328343
-
Hypoxic-ischemic encephalopathy
-
Philadelphia, PA: WB Saunders
-
Volpe J.J. Hypoxic-ischemic encephalopathy. Neurology of the Newborn. 1995;211-369 WB Saunders, Philadelphia, PA.
-
(1995)
Neurology of the Newborn
, pp. 211-369
-
-
Volpe, J.J.1
-
38
-
-
0032080673
-
Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury
-
Cheng Y., Desmukh M., D'Costa A., Demaro J.A., Gidday J.M., Shah A., Sun Y., Jacquin M.F., Johnson E.M., Holtzman D.M. Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. J. Clin. Invest. 101:1998;1992-1999.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1992-1999
-
-
Cheng, Y.1
Desmukh, M.2
D'Costa, A.3
Demaro, J.A.4
Gidday, J.M.5
Shah, A.6
Sun, Y.7
Jacquin, M.F.8
Johnson, E.M.9
Holtzman, D.M.10
-
39
-
-
0030991736
-
Marked age-dependent neuroprotection by brain-derived neurotrophic factor against neonatal hypoxic-ischemic brain injury
-
Cheng Y., Gidday J.M., Yan Q., Shah A.R., Holtzman D.M. Marked age-dependent neuroprotection by brain-derived neurotrophic factor against neonatal hypoxic-ischemic brain injury. Ann. Neurol. 41:1997;521-529.
-
(1997)
Ann. Neurol.
, vol.41
, pp. 521-529
-
-
Cheng, Y.1
Gidday, J.M.2
Yan, Q.3
Shah, A.R.4
Holtzman, D.M.5
-
40
-
-
0031056002
-
2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity
-
2+/ calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity. EMBO J. 16:1997;998-1008.
-
(1997)
EMBO J.
, vol.16
, pp. 998-1008
-
-
Cohen, O.1
Feinstein, E.2
Kimchi, A.3
-
41
-
-
0035955620
-
Identification of a new form of death associated protein kinase that promotes cell survival
-
Jin Y., Blue E.K., Dixon S., Hou L., Wysolmerski R.B., Gallagher P.J. Identification of a new form of death associated protein kinase that promotes cell survival. J. Biol. Chem. 276:2001;39667-39678.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39667-39678
-
-
Jin, Y.1
Blue, E.K.2
Dixon, S.3
Hou, L.4
Wysolmerski, R.B.5
Gallagher, P.J.6
-
42
-
-
0035816685
-
CEP-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family
-
Maroney A.C., Finn J.P., Connors T.J., Durkin J.T., Angeles T., Gessner G., Xu Z., Meyer S.L., Savage M.J., Greene L.A., Scott R.W., Vaught J.L. CEP-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family. J. Biol. Chem. 276:2001;25302-25308.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25302-25308
-
-
Maroney, A.C.1
Finn, J.P.2
Connors, T.J.3
Durkin, J.T.4
Angeles, T.5
Gessner, G.6
Xu, Z.7
Meyer, S.L.8
Savage, M.J.9
Greene, L.A.10
Scott, R.W.11
Vaught, J.L.12
-
43
-
-
0036139987
-
Inhibition of the c-jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons
-
Harris C.A., Deshmukh M., Tsui-Pierchala B., Maroney A.C., Johnson E.M. Jr. Inhibition of the c-jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. J. Neurosci. 22:2002;103-113.
-
(2002)
J. Neurosci.
, vol.22
, pp. 103-113
-
-
Harris, C.A.1
Deshmukh, M.2
Tsui-Pierchala, B.3
Maroney, A.C.4
Johnson, E.M.Jr.5
-
44
-
-
0030445778
-
Tripping the switch fantastic: How a protein kinase cascade can convert graded inputs into switch-like outputs
-
Ferrell J.E. Jr. Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs. Trends Biochem. Sci. 21:1996;460-466.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 460-466
-
-
Ferrell, J.E.Jr.1
-
45
-
-
0030848529
-
Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
-
Xu D.G., Crocker S.J., Doucet J.-P., St-Jean M., Tamai K., Hakim A.M., Ikeda J.E., Liston P., Thompson C.S., Korneluk R.G., MacKenzie A., Robertson G.S. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nat. Med. 3:1997;997-1004.
-
(1997)
Nat. Med.
, vol.3
, pp. 997-1004
-
-
Xu, D.G.1
Crocker, S.J.2
Doucet, J.-P.3
St-Jean, M.4
Tamai, K.5
Hakim, A.M.6
Ikeda, J.E.7
Liston, P.8
Thompson, C.S.9
Korneluk, R.G.10
MacKenzie, A.11
Robertson, G.S.12
-
46
-
-
0034808079
-
Ligand modulation of glial activation: Cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II
-
Watterson D.M., Mirzoeva S., Guo L., Whyte A., Bourguignon J.-J., Hibert M., Haiech J., Van Eldik L.J. Ligand modulation of glial activation: cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1β and nitric oxide synthase II. Neurochem. Int. 39:2001;459-468.
-
(2001)
Neurochem. Int.
, vol.39
, pp. 459-468
-
-
Watterson, D.M.1
Mirzoeva, S.2
Guo, L.3
Whyte, A.4
Bourguignon, J.-J.5
Hibert, M.6
Haiech, J.7
Van Eldik, L.J.8
-
47
-
-
0028348781
-
KT5926 inhibits nerve growth factor-dependent neurite elongation
-
Teng K.K., Greene L.A. KT5926 inhibits nerve growth factor-dependent neurite elongation. J. Neurosci. 14:1994;2624-2635.
-
(1994)
J. Neurosci.
, vol.14
, pp. 2624-2635
-
-
Teng, K.K.1
Greene, L.A.2
-
48
-
-
0023864240
-
K-252a: A specific inhibitor of the action of nerve growth factor on PC12 cells
-
Koizumi S., Contreras M.L., Matsuda Y., Hama T., Lazarovici P., Guroff G. K-252a: a specific inhibitor of the action of nerve growth factor on PC12 cells. J. Neurosci. 8:1988;715-721.
-
(1988)
J. Neurosci.
, vol.8
, pp. 715-721
-
-
Koizumi, S.1
Contreras, M.L.2
Matsuda, Y.3
Hama, T.4
Lazarovici, P.5
Guroff, G.6
-
49
-
-
0031737819
-
Search for new lead compounds: The example of the chemical and pharmacological dissection of aminopyridazines
-
Wermuth C.-G. Search for new lead compounds: the example of the chemical and pharmacological dissection of aminopyridazines. J. Heterocycl. Chem. 35:1998;1091-1100.
-
(1998)
J. Heterocycl. Chem.
, vol.35
, pp. 1091-1100
-
-
Wermuth, C.-G.1
-
50
-
-
0033963108
-
Apoptosis in neurologic disease
-
Honig L.S., Rosenberg R.N. Apoptosis in neurologic disease. Am. J. Med. 108:2000;317-330.
-
(2000)
Am. J. Med.
, vol.108
, pp. 317-330
-
-
Honig, L.S.1
Rosenberg, R.N.2
-
51
-
-
0035968923
-
Focal cerebral ischemia causes two temporal waves of Akt activation
-
Friguls B., Justicia C., Pallas M., Planas A.M. Focal cerebral ischemia causes two temporal waves of Akt activation. NeuroReport. 12:2001;3381-3384.
-
(2001)
NeuroReport
, vol.12
, pp. 3381-3384
-
-
Friguls, B.1
Justicia, C.2
Pallas, M.3
Planas, A.M.4
-
53
-
-
0036527429
-
Protein kinases - The major drug targets of the twenty-first century?
-
Cohen P. Protein kinases - the major drug targets of the twenty-first century? Nature Rev. 1:2002;309-315.
-
(2002)
Nature Rev.
, vol.1
, pp. 309-315
-
-
Cohen, P.1
-
54
-
-
0036591874
-
Structural biology in drug design: Selective protein kinase inhibitors
-
Scapin G. Structural biology in drug design: selective protein kinase inhibitors. Drug Discov. Today. 7:2002;601-611.
-
(2002)
Drug Discov. Today
, vol.7
, pp. 601-611
-
-
Scapin, G.1
-
55
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls S.A., Sharp K.A., Honig B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins. 11:1991;281-296.
-
(1991)
Proteins
, vol.11
, pp. 281-296
-
-
Nicholls, S.A.1
Sharp, K.A.2
Honig, B.3
|