Marine pharmacology in 1999: Compounds with antibacterial, anticoagulant, antifungal, anthelmintic, anti-inflammatory, antiplatelet, antiprotozoal and antiviral activities affecting the cardiovascular, endocrine, immune and nervous systems, and other miscellaneous mechanisms of action

Comparative Biochemistry and Physiology - C Toxicology and Pharmacology

Volumn 132, Issue 3, 2002, Pages 315-339

  Mayer, Alejandro M S ^a   Hamann, Mark T ^b  

^a MIDWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

1999; Marine; Pharmacology; Review; Secondary metabolites; Toxicology

Indexed keywords

15 ALPHA METHOXYPUUPEHENOL; AMPHILACTAM DERIVATIVE; ANTHELMINTIC AGENT; ANTICOAGULANT AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIPROTOZOAL AGENT; ANTITHROMBOCYTIC AGENT; ANTIVIRUS AGENT; BENGAMIDE; BENGAZOLE; FUCAN DERIVATIVE; GEODIN A; LOLOATIN A; LOLOATIN B; LOLOATIN C; LOLOATIN D; MAITOTOXIN; MYTICIN; OCEANAPISIDE; PSAMMAPLIN A; SPONGISTATIN I; TANIKOLIDE; TERPENE DERIVATIVE; THEOPEDERIN F; THEOPEDERIN G; THEOPEDERIN H; THEOPEDERIN J; UNCLASSIFIED DRUG; UNINDEXED DRUG; BIOLOGICAL FACTOR; CARDIOVASCULAR AGENT; CENTRAL NERVOUS SYSTEM AGENTS;

ALGA; ANTIBACTERIAL ACTIVITY; ANTICOAGULATION; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIPROTOZOAL ACTIVITY; ANTIVIRAL ACTIVITY; BACTERIOPLANKTON; CARDIOVASCULAR SYSTEM; DRUG ACTIVITY; DRUG MECHANISM; DRUG RESEARCH; ENDOCRINE SYSTEM; FIBRINOLYSIS; FUNGUS; IMMUNE SYSTEM; IMMUNOMODULATION; MARINE ENVIRONMENT; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; REVIEW; THROMBOCYTE AGGREGATION INHIBITION; ANIMAL; BIOLOGY; DRUG EFFECT; ENDOCRINE GLAND; HUMAN; PHARMACOLOGY;

ALGAE; ANIMALIA; FUNGI;

ANIMALS; ANTHELMINTICS; ANTI-BACTERIAL AGENTS; ANTICOAGULANTS; ANTIPROTOZOAL AGENTS; ANTIVIRAL AGENTS; BIOLOGICAL FACTORS; CARDIOVASCULAR AGENTS; CENTRAL NERVOUS SYSTEM AGENTS; ENDOCRINE GLANDS; HUMANS; IMMUNE SYSTEM; MARINE BIOLOGY; PHARMACOLOGY; PLATELET AGGREGATION INHIBITORS;

EID: 0036024405     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1532-0456(02)00094-7     Document Type: Review

References (85)

1. Revelation of antiviral activities by artificial sulfation of a glycosaminoglycan from a marine Pseudomonas
2. A new sulfated beta-galactan from clams with anti-HIV activity
3. Antiviral and anticoagulant activities of a water-soluble fraction of the marine diatom Haslea ostrearia
4. Antillatoxin and kalkitoxin, ichthyotoxins from the tropical cyanobacterium Lyngbya majuscula, induce distinct temporal patterns of NMDA receptor-mediated neurotoxicity
5. Screening of lipase inhibitors from marine algae
6. Adociasulfates 1-6, inhibitors of kinesin motor proteins from the sponge Haliclona (aka Adocia) sp
7. Methanol adduct of puupehenone, a biologically active derivative from the marine sponge Hyrtios species
8. Effects of equinatoxin II from Actinia equina (L.) on isolated rat heart: The role of direct cardiotoxic effects in equinatoxin II lethality
9. Heparin-binding molecules with growth factor activities in regenerating-tissues of the starfish Asterias rubens
10. Geodin A magnesium salt: A novel nematocide from a southern Australian marine sponge, Geodia
11. Characterization of antimicrobial agents extracted from Asterina pectinifera
12. Antibacterial activity of marine-derived fungi
13. Evaluation of the antiviral activity of natural sulfated polyhydroxysteroids and their synthetic derivatives and analogs
14. Effect of supplementation with dietary seal oil on selected cardiovascular risk factors and hemostatic variables in healthy male subjects
15. A new cytotoxic diterpene with the dolabellane skeleton from the marine sponge Sigmosceptrella quadrilobata
16. Kelletinin A, from the marine mollusc Buccinulum corneum, promotes differentiation in Hydra vulgaris
17. The biocatalytic transformation of furan to amide in the bioactive marine natural product palinurin
18. In vitro inhibition of the replication of haemorrhagic septicaemia virus (VHSV) and African swine fever virus (ASFV) by extracts from marine microalgae
19. Marine natural products
20. Antifungal metabolites from the marine sponge Pachastrissa sp.: New bengamide and bengazole derivatives
21. Papuamides A-D, HIV-inhibitory and cytotoxic depsipeptides from the sponges Theonella mirabilis and Theonella swinhoei collected in Papua New Guinea
22. A marine snail neurotoxin shares with scorpion toxins a convergent mechanism of blockade on the pore of voltage-gated K channels
23. Loloatins A-D, cyclic decapeptide antibiotics produced in culture by a tropical marine bacterium
24. Inhibition of membrane transport ATPases by halenaquinol, a natural cardioactive pentacyclic hydroquinone from the sponge Petrosia seriata
25. +)-ATPase by triterpene glycosides, psolusosides A and B from the holothurian Psolus fabricii
26. Keyhole limpet hemocyanin (KLH): A biomedical review
27. Carbohydrate-dependent hemolytic activity of the conjugate composed of a C-type lectin, CEL-I, and an amphiphilic alpha-helical peptide, 4(3)-beta Ala2
28. In vitro anti-methicillin-resistant Staphylococcus aureus activity found in extracts of marine algae indigenous to the coastline of Japan
29. Mechanism of inhibition of a poxvirus topoisomerase by the marine natural product sansalvamide A
30. Characterization of a palytoxin-induced non-selective cation channel in mouse megakaryocytes
31. 2+) release through sulfhydryl modification from skeletal muscle sarcoplasmic reticulum
32. Anabaenopeptins G and H, potent carboxypeptidase A inhibitors from the cyanobacterium Oscillatoria agardhii (NIES-595)
33. Potent antioxidant activity of a dithiocarbamate-related compound from a marine hydroid
34. Occurrence of highly yielded lectins homologous within the genus Eucheuma
35. Biologically active glycoside from Asteroidea, 38. Glycosphingolipids from the starfish Luidia maculata, 2
36. Sea anemone toxins as templates for the design of immunosuppressant drugs
37. Marine natural products as therapeutic agents [Review]
38. Psammaplin A, a natural bromotyrosine derivative from a sponge, possesses the antibacterial activity against methicillin-resistant Staphylococcus aureus and the DNA gyrase-inhibitory activity
39. Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons
40. Plocamium hamatum and its monoterpenes: Chemical and biological investigations of the tropical marine red alga
41. Maitotoxin-induced calcium influx in erythrocyte ghosts and rat glioma C6 cells, and blockade by gangliosides and other membrane lipids
42. +-dependent mechanism
43. Thyroglobulin type-1 domains in equistatin inhibit both papain-like cysteine proteinases and cathepsin D
44. Polycitone A, a novel and potent general inhibitor of retroviral reverse transcriptases and cellular DNA polymerases
45. 2+-dependent activation of ERK1 and ERK2 in cytotoxic responses induced by maitotoxin in breast cancer cells
46. Characterization of hemolytic activity of 3-alkylpyridinium polymers from the marine sponge Reniera sarai
47. A fibrinolytic enzyme from a marine green alga, Codium latum
48. Antiviral activities of marine Pseudomonas polysaccharides and their oversulfated derivatives
49. HIV reverse transcriptase inhibitors of natural origin
50. Genetically engineered obelin as a bioluminescent label in an assay for a peptide
51. Therapeutic implications of microglia activation by lipopolysaccharide and reactive oxygen species generation in septic shock and central nervous system pathologies: A review
52. Marine pharmacology in 1998: Marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, anthelmintic, antiplatelet, antiprotozoal, and antiviral activities; With actions on the cardiovascular, endocrine, immune, and nervous systems; And other miscellaneous mechanisms of action
53. Marine pharmacology in 1999: Antitumor and cytotoxic compounds
54. 2, and metalloprotease release
55. Myticin, a novel cysteine-rich antimicrobial peptide isolated from haemocytes and plasma of the mussel Mytilus galloprovincialis
56. 2 in rabbit platelet activation
57. 2+ in human astrocytoma cells
58. Oceanapiside, an antifungal bis-alpha,omega-amino alcohol glycoside from the marine sponge Oceanapia phillipensis
59. Effect of the hemolytic lectin CEL-III from Holothuroidea Cucumaria echinata on the ANS fluorescence responses in sensitive MDCK and resistant CHO cells
60. Iantheran A, a dimeric polybrominated benzofuran as a Na,K-ATPase inhibitor from a marine sponge, Ianthella sp
61. E.E. Just Lecture, 1996. Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology
62. Unusual antimicrotubule activity of the antifungal agent spongistatin 1
63. Amphilactams A-D: Novel nematocides from southern Australian marine sponges of the genus Amphimedon
64. 2
65. Structure and anticoagulant activity of sulfated fucans. Comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae
66. Homo- and nor-plakotenin, new carboxylic acids from the palauan sponge Plakortis lita
67. Isolation and structural determination of new sphingolipids and pharmacological activity of africanene and other metabolites from Sinularia leptoclados
68. Lamellarin alpha 20-sulfate, an inhibitor of HIV-1 integrase active against HIV-1 virus in cell culture
69. Polyketides from dinoflagellates: Origins, pharmacology and biosynthesis
70. A new isolation procedure and further characterisation of the lectin from the red marine alga Ptilota serrata
71. Sinulamide: An H,K-ATPase inhibitor from a soft coral Sinularia sp
72. Antitumor and cytotoxic compounds from marine organisms
73. Interaction of 3-alkylpyridinium polymers from the sea sponge Reniera sarai with insect acetylcholinesterase
74. Lyso-PAF analogues and lysophosphatidylcholines from the marine sponge Spirastrella abata as inhibitors of cholesterol biosynthesis
75. Sulphated polysaccharides of Codium dwarkense Boergs. from the west coast of India: Chemical composition and blood anticoagulant activity
76. Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula
77. Manoalide
78. New anti-actin drugs in the study of the organization and function of the actin cytoskeleton
79. Differential actions of pacific ciguatoxin-1 on sodium channel subtypes in mammalian sensory neurons
80. 2-andrenoceptor agonist from a marine sponge Dysidea sp
81. Roselipins, inhibitors of diacylglycerol acyltransferase, produced by Gliocladium roseum KF-1040
82. Theopederins F-J: Five new antifungal and cytotoxic metabolites from the marine sponge, Theonella swinhoei
83. Octa- and nonaprenylhydroquinone sulfates, inhibitors of alpha1,3-fucosyltransferase VII, from an Australian marine sponge Sarcotragus sp.
84. A new tyrosine kinase inhibitor from the marine brown alga Stypopodium zonale
85. Maitotoxin-induced free Ca changes in single rat hepatocytes