Isolation and structural determination of new sphingolipids and pharmacological activity of Africanene and other metabolites from Sinularia leptoclados

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 9, 1999, Pages 1214-1220

  Bala Show Reddy, G ^a   Venkata Rao, D ^b   Bheemasankara Rao, Ch ^b   Dhananjaya, N ^b   Kuttan, R ^c   Babu, T D ^c  

^a Trushna Exports Private Limited   (India)

^b ANDHRA UNIVERSITY   (India)

^c AMALA CANCER RESEARCH CENTRE   (India)

Author keywords

Africanene; Pharmacological study; Sinularia leptoclados; Soft coral; Sphingolipid; Toxicity

Indexed keywords

1,3,4 TRIACETOXY 2 [(2' ACETOXYOCTADECANOYL)AMINO]OCTADECANE; 1,3,4 TRIHYDROXY 2 [(2' HYDROXYTETRADECANOYL)AMINO]TRICOSANE; 23 NORGARGOSTEROL; AFRICANENE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIHYPERTENSIVE AGENT; ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; BATILOL; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CORAL; DOSE RESPONSE; DRUG CONFORMATION; DRUG EFFECT; DRUG ISOLATION; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

EID: 0344132072     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1214     Document Type: Article

References (42)

1. Anjaneyulu A. S. R., Venkateswara Rao G., J. Sci. Ind. Res., 54, 637 (1995).
2. Anjaneyulu A. S. R., Venkateswara Rao G., Nat. Prod. Sci., 1, 70 (1995).
3. Bhakuni D. S., J. Sci. Ind. Res., 49, 330 (1990).
4. Tillekratne L. M. V., Liyanage G. K., Ratnasooriya W. D., Schmitz F. J., Ksebati M. B., Hassner A., Amarasekhara A. S., Proc. of the 17th IUPAC Symp. on the Chem. Nat. Prod., 1990, 236.
5. Petit G. R., Fujie Y., J. Nat. Prod., 45, 640 (1982).
6. Pradeep Kumar S. V. A. S., Dhananjaya N., Reddy G. B. S., J. Chem. Res. (S), 1998, 404.
7. Kashman Y., Bodner M., Finer-Moore J. S., Clardy J., Experientia, 36, 891 (1980).
8. Breakman J. C., Daloze D., Tursch B., Hull S. E., Declercq J. P., Germain G., Meerssche V., Experientia, 36, 893 (1980).
9. Anjaneyulu A. S. R., Venkateswara Rao G., Saiprakash C. V. S., Indian J. Chem., 33B, 1165 (1994).
10. Jin W., Rinehart K. L., Jares-Erijman E. A., J. Org. Chem., 59, 144 (1994).
11. Hirsch S., Kashman Y., Tetrahedron, 45, 3897 (1989).
12. Natori T., Morita M., Akimoto K., Koezuka Y., Tetrahedron, 50, 2771 (1994).
13. Chebaane K., Guyot M., Tetrahedron Lett., 27, 1495 (1986).
14. Rao C. B. S., Satyanarayana Ch., Indian J. Chem., 33B, 97 (1994).
15. Shibuya H., Kurosu M., Minagawa K., Katayama S., Kitagawa I., Chem. Pharm. Bull., 41, 1534 (1993).
16. Zhao H., Zhao S., Guillaume D., Sun C., J. Nat. Prod., 57, 138 (1994).
17. Higuchi R., Natori T., Komori T., Justus Liebigs Ann. Chem., 1990, 51.
18. Signals taken from the S scale expansion spectra.
19. Author means the author of correspondence.
20. All other spectral data recorded was only for acetate derivative.
21. Kobayashi M., Krishna M. M., Haribabu B., Anjaneyulu V., Chem. Pharm. Bull., 41, 87 (1993).
22. Blanc P. A., Djerassi C., J. Am. Chem. Soc., 102, 7113 (1980).
23. Schmitz F. J., Pattabhiraman T., J. Am. Chem. Soc., 92, 6073 (1970).
24. 1H FT NMR Spectra," Vol. 1, 342A (1993).
25. Turner R. A. (ed.), "Screening Methods in Pharmacology," Demic Press, New York, 1965, p. 22.
26. Irwin S., Gordon Res. Conf. on Medicinal Chem., 1959, 133.
27. Turner R. A. (ed.), "Screening Methods in Pharmacology," Demic Press, New York, 1965, pp. 42-140.
28. Ghosh M. N. (ed.), "Fundamentals of Experimental Pharmacology," Scientific Book Agency, Pondicherry , India, edn. 2, p. 130.
29. Turner R. A. (ed.), "Screening Methods in Pharmacology," Demic Press, New York, 1965, p. 55.
30. Nieschulz O., Hoffmann I., Popendiker K., Arzneimittel-Forsch., 6, 651 (1956); idem, ibid., 7, 106 (1957).
31. Nieschulz O., Hoffmann I., Popendiker K., Arzneimittel-Forsch., 6, 651 (1956); idem, ibid., 7, 106 (1957).
32. Smith W. G., "Progress in Medicinal Chemistry," ed. by Ellis G. P., West G. B., Butterworth, Washington, D.C., Vol. 1, 1961, Chap. 1.
33. Winter C. A., Risley E. A., Nuss G. W., Proc. Soc. Exp. Biol. Med., 111, 544 (1962).
34. Snedecor G. W., Cochran W. G. (ed.), "Statistical Methods," The Iowa State Univ. Press, Ames, U.S.A., edn. 6, 1967, p. 546.
35. Ghosh M. N. (ed.), "Fundamentals of Experimental Pharmacology," Scientific Book Agency, Pondicherry, India, edn. 2, p. 177.
36. Kuttan R., Bhanumathi P., Nirmala R., George M. C., Cancer Lett., 29, 197 (1985).
37. Kuttan G., Vasudevan D. M., Kuttan R., Cancer Lett., 41, 307 (1988).
38. Ruby J. A., Girija K., Dinesh Babu K. V., Rajasekharan K. N., Ramadasan K., Int. J. Pharm., 131, 1 (1996).
39. Pushpangadan P., Rajasekharan S., Subramoniam A., Latha P. G., Evans D. A., Valsaraj R., Ancient Sci. Life, 14, 127 (1995).
40. Kavanagh E. (ed.), "Analytical Microbiology," Academic Press, New York, 1963, p. 249.
41. Cruickshank R., Duguid J. P., Swain R. H. A. (ed.), "The Practice of Medical Microbiology," Churchill Livingstone, London, edn. 12, Vol. 2, 1975, pp. 110-126.
42. Sudakara Rao T., "Structural Elucidation and Biological Evaluation of Metabolites of Some Alcyonarians of the Andaman and Nicobar Islands," Thesis Submitted to Andhra University, Visakhapatnam, India, 1992, p. 289.