Roselipins, inhibitors of diacylglycerol acyltransferase, produced by Gliocladium roseum KF-1040

Journal of Antibiotics

Volumn 52, Issue 8, 1999, Pages 689-694

  Tomoda, Hiroshi ^a   Ohyama, Yukako ^a   Abe, Tatsuo ^b   Tabata, Noriko ^a   Namikoshi, Michio ^b   Yamaguchi, Yuichi ^a   Masuma, Rokuro ^a   Omura, Satoshi ^a  

^a KITASATO UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL ACYLTRANSFERASE; ENZYME INHIBITOR; ROSELIPIN; SEA WATER; UNCLASSIFIED DRUG;

ARTICLE; COLUMN CHROMATOGRAPHY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION; FERMENTATION; FUNGUS; FUNGUS CULTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL;

GLIOCLADIUM ROSEUM;

EID: 0032864381     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.689     Document Type: Article

References (9)

1. MAYOREK, N. & J. BAR-TANA: Inhibition of diacylglycerol acyltransferase by 2-bromooctanoate in cultured rat hepatocytes. J. Biol. Chem. 260: 6528-6532, 1985
2. BELL, R. M. & R. A. COLEMAN: Enzymes of triacylglycerol formation in mammals. Enzymes 16: 87-111, 1983
3. TOMODA, H.; M. ITO, N. TABATA, R. MASUMA, Y. YAMAGUCHI & S. ŌMURA: Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. J. Antibiotics 48: 937-941, 1995
4. TOMODA, H.; N. TABATA, M. Ito & S. ŌMURA: Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. II. Structure elucidation of amidepsines A, B and C. J. Antibiotics 48: 942-947, 1995
5. TOMODA, H.; Y. YAMAGUCHI, N. TABATA, T. KOBAYASHI, R. MASUMA, H. TANAKA, & S. ŌMURA: Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969. J. Antibiotics 49: 929-931, 1996
6. TABATA, N.; M. ITO, H. TOMODA & S. ŌMURA: Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus. Phytochemistry 46: 683-687, 1997
7. OMURA, S.; H. TOMODA, N. TABATA, Y. OHYAMA, T. ABE & M. NAMIKOSHI: Roselipins, novel fungal metabolites having a highly methylated fatty acid modified with a mannose and an arabinitol. J. Antibiotics 52: 586-589, 1999
8. TABATA, N.; Y. OHYAMA, H. TOMODA, T. ABE, M. NAMIKOSHI & S. ŌMURA: Structure elucidation of roselipins produced by Gliocladium roseum KF-1040. J. Antibiotics, in press
9. DOMSCH, K. H.; W. GAMS & T-H. ANDERSON: Gliocladium roseum. In Compendium of Soil Fungi. pp. 371-374, Academic Press, London, 1980