A 7-kDa Prion Protein (PrP) Fragment, an Integral Component of the PrP Region Required for Infectivity, Is the Major Amyloid Protein in Gerstmann-Sträussler-Scheinker Disease A117V

Journal of Biological Chemistry

Volumn 276, Issue 8, 2001, Pages 6009-6015

  Tagliavini, Fabrizio ^a   Lievens, Patricia M J ^a   Tranchant, Christine ^b   Warter, Jean Marie ^b   Mohr, Michel ^b   Giaccone, Giorgio ^a   Perini, Francesco ^a   Rossi, Giacomina ^a   Salmona, Mario ^c   Piccardo, Pedro ^d   Ghetti, Bernardino ^d   Beavis, Ronald C ^e   Bugiani, Orso ^a   Frangione, Blas ^e   Prelli, Frances ^e  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

^b UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BRAIN; DISEASES; GENES; MASS SPECTROMETRY; MUTAGENESIS; TISSUE;

AMYLOID FORMATION;

PROTEINS;

AMYLOID; AMYLOID PROTEIN; ARGININE; ASPARAGINE; GLUTAMIC ACID; GLYCINE; PRION PROTEIN; PROTEINASE; VALINE; INFECTIOUS AMYLOID PRECURSOR PROTEIN; METHIONINE; PEPTIDE FRAGMENT; PRNP PROTEIN, HUMAN; PROTEIN PRECURSOR;

ADULT; ARTICLE; CASE REPORT; FIBER; GENE MUTATION; GERSTMANN STRAUSSLER SCHEINKER SYNDROME; HETEROZYGOSITY; HUMAN; INFECTION; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; VASCULAR AMYLOIDOSIS; ALLELE; BRAIN CORTEX; GENETICS; HETEROZYGOTE; ISOLATION AND PURIFICATION; PATHOGENICITY; PATHOLOGY; PRION; SYNDROME;

ADULT; ALLELES; AMYLOID; CEREBRAL CORTEX; GERSTMANN-STRAUSSLER-SCHEINKER DISEASE; HETEROZYGOTE; HUMANS; MALE; METHIONINE; PEPTIDE FRAGMENTS; PRIONS; PROTEIN PRECURSORS; SEQUENCE ANALYSIS, PROTEIN; SYNDROME; VALINE;

EID: 0035937094     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007062200     Document Type: Article

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