A Conserved Docking Site in MEKs Mediates High-affinity Binding to MAP Kinases and Cooperates with a Scaffold Protein to Enhance Signal Transmission

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 10374-10386

  Jane Bardwell, A ^a   Flatauer, Laura J ^a   Matsukuma, Karen ^a   Thorner, Jeremy ^b   Bardwell, Lee ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENES; MUTAGENESIS; YEAST;

CONSERVED DOCKING;

ENZYMES;

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN STE7; UNCLASSIFIED DRUG; CARRIER PROTEIN; FUNGAL PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; PEPTIDE; PHEROMONE; PROTEIN KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; STE5 PROTEIN, S CEREVISIAE; STE7 PROTEIN, S CEREVISIAE;

ALLELE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; YEAST CELL; AMINO ACID SEQUENCE; BINDING SITE; BIOLOGICAL MODEL; CHEMISTRY; DOSE RESPONSE; FUNGAL GENE; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; OPEN READING FRAME; PHOSPHORYLATION; PLASMID; PROTEIN BINDING; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ANIMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALLELES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CARRIER PROTEINS; CONSERVED SEQUENCE; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGAL PROTEINS; GENES, FUNGAL; GLUTATHIONE TRANSFERASE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; PEPTIDES; PHEROMONES; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 0035971144     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010271200     Document Type: Article

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