Prodomain Processing of Asp1 (BACE2) Is Autocatalytic

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 23322-23328

  Hussain, Ishrut ^a   Christie, Gary ^a   Schneider, Klaus ^a   Moore, Stephen ^a   Dingwall, Colin ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOSYNTHESIS; CELL MEMBRANES; DISEASES; POLYPEPTIDES;

TRANSMEMBRANES;

ENZYMES;

AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BETA SECRETASE; GAMMA SECRETASE; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; MEMBRANE PROTEIN; BETA SITE APP CLEAVING ENZYME 2; BETA-SITE APP CLEAVING ENZYME 2; CARRIER PROTEIN; ENZYME PRECURSOR; HISTIDINE; MALTOSE-BINDING PROTEIN; PEPTIDE; POLYHISTIDINE; PROTEINASE; SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BIOTINYLATION; CATALYSIS; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENETIC TRANSFECTION; GOLGI COMPLEX; MASS SPECTROMETRY; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; AMINO ACID SEQUENCE; ANIMAL; CELL STRAIN COS1; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PH; PROTEIN TERTIARY STRUCTURE;

ANIMALIA;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CARRIER PROTEINS; CATALYSIS; COS CELLS; ENDOPEPTIDASES; ENZYME PRECURSORS; HISTIDINE; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 0035968173     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101069200     Document Type: Article

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