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Volumn 66, Issue 26, 2001, Pages 8815-8830

Elongated multiple electronic cascade and cyclization spacer systems in activatible anticancer prodrugs for enhanced drug release

(9) De Groot, F M H a Loos, W J a,b Koekkoek, R a Van Berkom, L W A a Busscher, G F a Seelen, A E a Albrecht, C a De Bruijn, P a,b Scheeren, H W a

a RADBOUD UNIVERSITY NIJMEGEN (Netherlands)

b ERASMUS MEDICAL CENTER (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PRODRUGS; SPACER SYSTEMS;

AMINES; DERIVATIVES; NAPHTHALENE;

SYNTHESIS (CHEMICAL);

ANTINEOPLASTIC AGENT; BIPHENYL DERIVATIVE; DOXORUBICIN DERIVATIVE; NAPHTHALENE DERIVATIVE; PACLITAXEL DERIVATIVE; PLASMIN; PRODRUG;

ARTICLE; CANCER CHEMOTHERAPY; CATALYSIS; CHEMICAL STRUCTURE; CYCLIZATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG STABILITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CARBAMATES; CYCLIZATION; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTRONS; HUMANS; HYDROLYSIS; INDICATORS AND REAGENTS; KINETICS; OLIGOPEPTIDES; PACLITAXEL; PLASMIN; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0035966194 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo0158884 Document Type: Article

Times cited : (99)

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