Combinatorial library of serine and cysteine protease inhibitors that interact with both the S and S' binding sites

Journal of Medicinal Chemistry

Volumn 42, Issue 19, 1999, Pages 4001-4009

  Abato, Paul ^a   Conroy, Jeffrey L ^a   Seto, Christopher T ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; CATHEPSIN B; CYCLOHEXANONE DERIVATIVE; CYSTEINE PROTEINASE INHIBITOR; PAPAIN; PLASMIN; SERINE PROTEINASE INHIBITOR; TRYPTOPHAN; TYROSINE;

ARTICLE; DRUG BINDING SITE; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME SPECIFICITY; HYDROPHOBICITY;

BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE PROTEINASE INHIBITORS; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; PEPTIDE LIBRARY; SERINE PROTEINASE INHIBITORS; SUBSTRATE SPECIFICITY;

EID: 0033598321     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990272g     Document Type: Article

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