Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 23, 1998, Pages 3341-3346

  Dubowchik, Gene M ^a   Firestone, Raymond A ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; ANTINEOPLASTIC AGENT; BMS 182248; CATHEPSIN B; DIPEPTIDE; DOXORUBICIN; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CANCER CHEMOTHERAPY; CANCER IMMUNOTHERAPY; DRUG HALF LIFE; DRUG RELEASE; DRUG STABILITY; ENZYME SUBSTRATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METASTASIS; PLASMA;

EID: 0032402354     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00609-X     Document Type: Article

References (19)

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