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Volumn 91, Issue 4, 2001, Pages 550-554

Pronounced antitumor efficacy of doxorubicin when given as the prodrug DOX-GA3 in combination with a monoclonal antibody β-glucuronidase conjugate

(7) Houba, P H J a,b Boven, E a,c Van Der Meulen Muileman, I H a Leenders, R G G a,b Scheeren, J W a,b Pinedo, H M a,b Haisma, H J a,b

a VU UNIVERSITY MEDICAL CENTER (Netherlands)

b RADBOUD UNIVERSITY NIJMEGEN (Netherlands)

c UNIVERSITY OF GRONINGEN (Netherlands)

Author keywords

ADEPT; Anthracyclines; Antibody directed enzyme prodrug therapy; Selective chemotherapy

Indexed keywords

BETA GLUCURONIDASE; CARBAMIC ACID DERIVATIVE; CELL ADHESION MOLECULE; DOXORUBICIN; MONOCLONAL ANTIBODY; N [4 DOXORUBICIN N CARBONYL(OXYMETHY)PHENYL] O BETA GLUCURONYLCARBAMATE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER REGRESSION; CONJUGATE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; TREATMENT OUTCOME; TUMOR NECROSIS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BODY WEIGHT; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; FEMALE; GLUCURONIC ACIDS; GLUCURONIDASE; HUMANS; MAXIMUM TOLERATED DOSE; MEMBRANE GLYCOPROTEINS; MICE; MICE, NUDE; MODELS, CHEMICAL; NECROSIS; NEOPLASM TRANSPLANTATION; NEOPLASMS; OVARIAN NEOPLASMS; PRODRUGS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0035866038 PISSN: 00207136 EISSN: None Source Type: Journal
DOI: 10.1002/1097-0215(200002)9999:9999<::AID-IJC1075>3.0.CO;2-L Document Type: Article

Times cited : (56)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.