NMR Spectroscopy Reveals the Solution Dimerization Interface of p53 Core Domains Bound to Their Consensus DNA

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 49020-49027

  Klein, Christian ^a,b   Planker, Eckart ^c,d   Diercks, Tammo ^c,d   Kessler, Horst ^c,d   Künkele, Klaus Peter ^a   Lang, Kurt ^a   Hansen, Silke ^a   Schwaiger, Manfred ^a  

^a ROCHE DIAGNOSTICS GMBH   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c Novaspin Biotech GmbH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; DIMERIZATION; DNA; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TUMORS;

TRANSCRIPTION FACTORS;

PROTEINS;

DNA; PROTEIN P53; TRANSCRIPTION FACTOR;

ARTICLE; DNA BINDING; DNA PROTEIN COMPLEX; FLUORESCENCE SPECTROSCOPY; HUMAN; HYDRODYNAMICS; MOLECULAR CLONING; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PURIFICATION; TUMOR SUPPRESSOR GENE; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DIMERIZATION; MACROMOLECULE; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN QUATERNARY STRUCTURE; SOLUTION AND SOLUBILITY;

MAMMALIA;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITES; DIMERIZATION; DNA; HUMAN; MACROMOLECULAR SYSTEMS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN P53; PROTEIN STRUCTURE, QUATERNARY; SOLUTIONS;

EID: 0035966083     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107516200     Document Type: Article

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