Thermodynamic stability of wild-type and mutant p53 core domain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 26, 1997, Pages 14338-14342

  Bullock, Alex N ^a   Henckel, Julia ^a   Dedecker, Brian S ^a   Johnson, Christopher M ^a   Nikolova, Penka V ^a   Proctor, Mark R ^a   Lane, David P ^b   Fersht, Alan R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Denaturation; Folding; Protein; Tumor suppressor; Zinc

Indexed keywords

PROTEIN P53;

ARTICLE; GENE MUTATION; HUMAN; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN STABILITY; THERMODYNAMICS; TUMOR SUPPRESSOR GENE;

ANIMALS; GENES, TUMOR SUPPRESSOR; HUMANS; MUTATION; THERMODYNAMICS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031447171     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.26.14338     Document Type: Article

References (22)

1. Lane, D. P. (1992) Nature (London) 358, 15-16.
2. Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B. & Craig, R. W. (1991) Cancer Res. 51, 6304-6311.
3. Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W. & Vogelstein, B. (1997) Nature (London) 389, 300-305.
4. Ciechanover, A., Shkedy, D., Oren, M. & Bercovich, B. (1994) J. Biol. Chem. 269, 9582-9589.
5. Haupt, Y., Maya, R., Kazaz, A. & Oren, M. (1997) Nature (London) 387, 296-299.
6. Pavletich, N. P., Chambers, K. A. & Pabo, C. O. (1993) Genes Dev. 7, 2556-2564.
7. Cho, Y., Gorina, S., Jeffrey, P. D. & Pavletich, N. P. (1994) Science 265, 346-355.
8. Rolley, N., Butcher, S. & Milner, J. (1995) Oncogene 11, 763-770.
9. Friedlander, P., Legros, Y., Soussi, T. & Prives, C. (1996) J. Biol. Chem. 271, 25468-25478.
10. Milner, J., Cook, A. C. & Sheldon, M. (1987) Oncogene 1, 453-455.
11. Clarke, J. & Fersht, A. R. (1993) Biochemistry 32, 4322-4329.
12. Serrano, L., Kellis, J. T., Jr., Cann, P., Matouschek, A. & Fersht, A. R. (1992) J. Mol. Biol. 224, 783-804.
13. Shortle, D., Stites, W. E. & Meeker, A. K. (1990) Biochemistry 29, 8033-8041.
14. Santoro, M. M. & Bolen, D. W. (1992) Biochemistry 31, 4901-4907.
15. Midgley, C. A., Fisher, C. J., Bartek, J., Vojtesek, B., Lane, D. & Barnes, D. (1992) J. Cell Sci. 101, 183-189.
16. Gili, S. C. & von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326.
17. Pace, C. N. (1986) Methods Enzymol. 131, 266-279.
18. Rainwater, R., Parks, D., Anderson, M. E., Tegtmeyer, P. & Mann, K. (1995) Mol. Cell. Biol. 15, 3892-3903.
19. Cornell, N. W. & Crivaro, K. E. (1972) Anal. Biochem. 47, 203-208.
20. Hunt, J. B., Neece, S. H. & Ginsburg, A. (1985) Anal. Biochem. 146, 150-157.
21. Fersht, A. R. & Serrano, L. (1993) Curr. Opin. Struct. Biol. 3, 75-83.
22. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.