Blocking of c-FLIPL-independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction

Blood

Volumn 98, Issue 4, 2001, Pages 925-933

  Youn, Byung S ^a,b,c   Kim, Young J ^a,b   Mantel, Charlie ^a,b   Yu, Kang Yeol ^a,b   Broxmeyer, Hal E ^a,b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CASPASE 3; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR9; CHEMOKINE RECEPTOR CXCR4; CYCLOHEXIMIDE; FAS ANTIBODY; FAS ANTIGEN; FLICE INHIBITORY PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STROMAL CELL DERIVED FACTOR 1; THYMUS EXPRESSED CC CHEMOKINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CHEMOTAXIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LYMPHOID CELL LINE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0035883065     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V98.4.925     Document Type: Article

References (50)

1. Ward SG, Bacon KB, Westwick J. Chemokine and T lymphocytes: more than attraction. Immunity. 1998;9:1-11.
2. Rossi D, Zlotnik A. The biology of chemokines and their receptors. Ann Rev Immunol. 2000;18:217-242.
3. Vila-Coro AJ, Rodriguez-Frade JM, Martin De Ana A, Moreno-Ortiz MC, Martinez-AC, Mellado M. The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB J. 1999;13:1699-1710.
4. Majka M, Janowska-Wieczorek A, Ratajczak J, Kowalska MA, Vilaire G, Pan ZK, Honczarenko M, Marquez LA, Poncz M, Ratajczak MZ. Stromal-derived factor 1 and thrombopoetin regulate distinct aspects of human megakaryopolesis. Blood. 2000;96:4142-4151.
5. Ganju RK, Dutt P, Wu L, et al. Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK. Blood. 1998;91:791-797.
6. Turner L, Ward SG, Westwick J. RANTES-activated human T lymphocytes: a role for phosphoinositide 3-kinase. J Immunol. 1995;155:2437-2444.
7. Turner SJ, Domin J, Waterfield MD, Ward SG, Westwick J. The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II P13K-C2alpha. J Biol Chem. 1998;273:25987-25995.
8. Kampen GT, Stafford S, Adachi T, et al. Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogen-activated protein kinases. Blood. 2000;15:1911-1917.
9. Boehme SA, Sullivan SK, Crowe PD, et al. Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration. J Immunol. 1999;163:1611-1618.
10. Wang JF, Park IW, Groopman JE. Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood. 2000;95:2505-2513.
11. Youn BS, Mantel C, Broxmeyer HE. Chemokines, chemokine receptors and hematopoiesis. Immunol Rev. 2000;177:150-174.
12. Youn BS, Kim CH, Smith FO, Broxmeyer HE. TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor. Blood. 1999;94:2533-2536.
13. Zaballos A, Gutierrez J, Varona R, Ardavin C, Marquez G. Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J Immunol. 1999;162:5671-5675.
14. Zabel BA, Agace WW, Campbell JJ, et al. Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med. 1999;190:1241-1256.
15. Rommel C, Clarke BA, Zimmermann S, et al. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science. 1999;286:1738-1741.
16. Vanhaesebroeck B, Jones GE, Allen WE, et al. Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages. Nat Cell Biol. 1999;1:69-71.
17. Yujiri T, Ware M, Widmann C, et al. MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation. Proc Natl Acad Sci U S A. 2000;97:7272-7277.
18. Vicente-Manzanares M, Rey M, Jones DR, et al. Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis. J Immunol. 1999;163:4001-4012.
19. Yen H, Zhang Y, Penfold S, Rollins BJ. MCP-1-mediated chemotaxis requires activation of nonoverlapping signal transduction pathways. J Leukoc Biol. 1997;61:529-532.
20. Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev. 1999;13:2905-2927.
21. Klippel A, Kavanaugh WM, Pot D, Williams LT. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain. Mol Cell Biol. 1997;17:338-344.
22. Gosling J, Dairaghi DJ, Wang Y, et al. Cutting edge: identification of a novel chemokine receptor that binds dendritic cell- and T cell-active chemokines including ELC, SLC, and TECK. J Immunol. 2000;164:2851-2856.
23. Lopez-Llasaca M, Crespo P, Giuseppe Pellici P, Gutkind JS, Wetzker R. Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma. Science. 1997;275:394-397.
24. Sasaki T, Irie-Sasaki J, Jones RG, et al. Function of P13K′ in thymocyte development, T cell activation, and neutrophil migration. Science. 2000;287:1040-1046.
25. Hausler P, Papoff G, Eramo A, Reif K, Cantrell DA, Ruberti G. Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B. Eur J Immunol. 1998;28:57-69.
26. Yeh J-H, Hsu S-C, Han S-H, Lai M-Z. Mitogenactivated protein kinase kinase antagonized Fasassociated death domain protein-mediated apoptosis by induced FLICE-inhibitory protein expression. J Exp Med. 1998;188:1795-1802.
27. Tatsuta T, Cheng J, Mountz JD. Intracellular IL-1 beta is an inhibitor of Fas-mediated apoptosis. J Immunol. 1996;157:3949-3957.
28. + thymocytes by the anti-Fas antibody. J Exp Med. 1995;181:485-491.
29. L and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisidolylmaleimide. Blood. 2000;95:3478-3482.
30. Wajant H, Hass E, Schwenzer R, et al. Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD). J Biol Chem. 2000;275:24357-24366.
31. Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 1998;281:1680-1683.
32. Romahkova JA, Makarov SS. NF-kappaB is a target of AKT in anti-apoptotic PDGF signaling. Nature. 1999;401:86-90.
33. Ganju RK, Brubaker SA, Meyer J, et al. The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR4 receptor and activates multiple signal transduction pathways. J Biol Chem. 1998;273:23169-23175.
34. Woo M, Hakem R, Soengas MS, et al. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 1998;12:806-819.
35. s. Proc Natl Acad Sci U S A. 1997;94:14489-14494.
36. Toker A, Cantley LC. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature. 1997;387:673-676.
37. Hirsch E, Katanaev VL, Garlanda C, et al. Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation. Science. 2000;287:1049-1053.
38. Li Z, Jiang Z, Smarca AV, Wu D. Roles of PLC-β2 and -β3 and PI3Kγ in chemoattractant signal transduction. Science, 2000;287:1046-1049.
39. Dudek H, Datta SR, Franke TF, et al. Regulation of neuronal survival by the serine-threonie protein kinase Akt. Science. 1997;275:661-665.
40. Tilton B, Andjelkovic M, Didichenko SA, Hemmings BA, Thelen M. G-protein-coupled receptors and Fc gamma-receptors mediate activation of Akt/protein kinase B in human phagocytes. J Biol Chem. 1997;272:28096-28101.
41. Sotsios Y, Whittaker GC, Westwick J, Ward SG. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J Immunol. 1999;163:5954-5963.
42. Coffer PJ, Schweizer RC, Dubois GR, Maikoe T, Lammers JW, Koenderman L. Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin-5. Blood. 1998;91:2547-2557.
43. Servant G, Weiner OD, Herzmark P, Balla T, Sedat JW, Boune HR. Polarization of chemoattractant receptor signaling during neutrophil chemotaxis. Science. 2000;87:1037-1040.
44. Shi Y, Frankel A, Radvanyi LG, Penn LZ, Miller RG, Mills GB. Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro. Cancer Res. 1995;55:1982-1988.
45. Arai H, Charo IF. Differential regulation of G-protein-mediated signaling by chemokine receptors. J Biol Chem. 1996;271:21814-21819.
46. Yusta B, Boushey RP, Drucker DJ. The glucagon-like peptide-2 receptor mediates direct inhibition of cellular apoptosis via a cAMP-dependent protein kinase-independent pathway. J Biol Chem. 2000;275:35345-35352.
47. Leloup C, Michaelson DM, Fisher A, Hartmann T, Beyreuther K, Stein R. M1 muscarinic receptors block caspase activation by phosphoinositide 3-kinase- and MAPK/ERK-independent pathways. Cell Death Differ. 2000;7:825-833.
48. Gu C, Ma YC, Benjamin J, Chao MV, Huang XY. Apoptotic signaling through the beta-adrenergic receptor: a new Gs effector pathway. J Biol Chem. 2000;275:20726-20733.
49. Turner PR, Mefford S, Christakos S, Nissenson RA. Apoptosis mediated by activation of the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein (PTHrP). Mol Endocrinol. 2000;14:241-254.
50. Tang D, Lahti JM, Grenet J, Kidd VJ. Cycloheximide-induced T-cell death is mediated by a Fasassociated death domain-dependent mechanism. J Biol Chem. 1999;274:7245-7252.