The importance of framework residues H6, H7 and H10 in antibody heavy chains: Experimental evidence for a new structural subclassification of antibody VH domains

Journal of Molecular Biology

Volumn 309, Issue 3, 2001, Pages 701-716

  Jung, Sabine ^a,b   Spinelli, Silvia ^a,b   Schimmele, Bernhard ^a,b   Honegger, Annemarie ^a,b   Pugliese, Luisa ^a,b   Cambillau, Christian ^a,b   Plückthun, Andreas ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b CNRS   (France)

Author keywords

Ampicillin; Antibody engineering; Framework Structure; Immunoglobulin variable domains; scFv

Indexed keywords

AMINO ACID; IMMUNOGLOBULIN HEAVY CHAIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBODY AFFINITY; ANTIBODY STRUCTURE; ARTICLE; CONCENTRATION RESPONSE; DIMERIZATION; FLUORESCENCE; MOLECULAR CLONING; MUTATION; NOMENCLATURE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; THERMODYNAMICS; X RAY ANALYSIS;

EID: 0035827149     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4665     Document Type: Article

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