Different equilibrium stability behavior of scFv fragments: Identification, classification, and improvement by protein engineering

Biochemistry

Volumn 38, Issue 27, 1999, Pages 8739-8750

  Wörn, Arne ^a   Plückthun, Andreas ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEINASE;

ARTICLE; DENATURATION; GEL FILTRATION; GENETIC ENGINEERING; LIGHT SCATTERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; THERMOSTABILITY;

CHROMATOGRAPHY, GEL; ENDOPEPTIDASES; GENETIC VECTORS; GUANIDINE; HUMANS; HYDROLYSIS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; PROTEIN DENATURATION; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TEMPERATURE; THERMOLYSIN; UREA;

EID: 0040964401     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9902079     Document Type: Article

References (41)

1. Bird, R. E., Hardman, K. D., Jacobson, J. W., Johnson, S., Kaufman, B. M., Lee, S. M., Lee, T., Pope, S. H., Riordan, G. S., and Whitlow, M. (1988) Science 242, 423-426.
2. Huston, J. S., Levinson, D., Mudgett-Hunter, M., Tai, M., Novotny, J., Margolies, M. N., Ridge, R. J., Bruccoleri, R. E., Haber, E., Crea, R., and Oppermann, H. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 5879-5883.
3. Plückthun, A., Krebber, A., Horn, U., Knüpfer, U., Wenderoth, R., Nieba, L., Proba, K., and Riesenberg, D. (1996) in Antibody Engineering, A Practical Approach (McCafferty, J., Hoogenboom, H. R., and Chiswell, D. J., Eds.) pp 203-252, IRL press, Oxford University Press, New York.
4. Glockshuber, R., Malia, M., Pfitzinger, T., and Plückthun, A. (1990) Biochemistry 29, 1362-1367.
5. Bregegere, F., England, P., Djavadi-Ohaniance, L., and Bedouelle, H. (1997) J. Mol. Recognit. 10, 169-181.
6. Behar, I., and Pastan, I. (1995) J. Biol. Chem. 270, 23373-23380.
7. Pace, C. N., Shirley, B. A., and Thomson, J. A. (1989) in Protein Structure, A Practical Approach (Creighton, T. E., Ed.) pp 311-330, IRL-Press, Oxford University Press.
8. Eftink, M. R. (1994) Biophys. J. 66, 482-501.
9. Worn, A., and Plückthun, A. (1998) Biochemistry 37, 13120-13127.
10. Rudikoff, S., and Pumphrey, J. G. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 7875-7878.
11. Proba, K., Honegger, A., and Plückthun, A. (1997) J. Mol. Biol. 265, 161-172.
12. Proba, K., Worn, A., Honegger, A., and Plückthun, A. (1998) J. Mol. Biol. 275, 245-253.
13. Kelley, R. F., O'Connell, M. P., Carter, P., Presta, L., Eigenbrot, C., Covarrubias, M., Snedecor, B., Bourell, J. H. and Vetterlein, D. (1992) Biochemistry 31, 5434-5441.
14. Wörn, A., and Plückthun, A. (1998) FEBS Lett. 427, 357-361.
15. Kabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S., and Foeller, C. (1991) NIH Publication No. 91-3242, National Institute of Health, Bethesta, MD.
16. Spada, S., Honegger, A., and Plückthun, A. (1998) J. Mol. Biol. 283, 395-407.
17. Brinkmann, U., Reiter, Y., Jung, S.-H., Lee, B., and Pastan, I. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 7538-7542.
18. Ge, L., Knappik, A., Pack, P., Freund, C., and Plückthun, A. (1995) in Antibody Engineering (Borrebaeck, C. A. K., Ed.) 2nd ed., pp 229-266, IRL Press, Oxford University Press.
19. Freund, C., Ross, A., Guth, B., Plückthun, A., and Holak, T. A. (1993) FEBS Lett. 320, 97-100.
20. Studier, F. W., and Moffatt, B. A. (1986) J. Mol. Biol. 189, 113-130.
21. Knappik, A., Krebber, C., and Plückthun, A. (1993) Biotechnology 11, 77-83.
22. Knappik, A., and Plückthun, A. (1994) Biotechniques 17, 754-761.
23. Tang, Y., Jiang, N., Parakh, C., and Hilvert, D. (1996) J. Biol. Chem. 271, 15682-15686.
24. Heinrikson, R. L. (1977) Methods Enzymol. 47, 175-189.
25. Chrunyk, B. A., and Wetzel, R. (1993) Protein Eng. 6, 733-738.
26. Cowgill, R. W. (1967) Biochem. Biophys. Acta 140, 37-41.
27. Jäger, M., and Plückthun, A. (1999) J. Mol. Biol. 285, 2005-2019.
28. Schmid, F. X. (1997) in Protein Structure, A Practical Approach (Creighton, T. E., Ed.) 2nd ed., pp 261-297, IRL Press, Oxford University Press.
29. Brandts, J. F., Hu, C. Q., and Lin, L. N. (1989) Biochemistry 28, 8588-8596.
30. Eftink, M. R. (1991) in Methods of biochemical analysis (Suelter, C. H., Ed.) Vol. 35, J. Wiley, New York.
31. Cantor, C., and Schimmel, P. R. (1980) Biophysical Chemistry, Vol. II, pp 433-465, Freeman, W. H., San Francisco.
32. Pace, C. N. (1990) Trends Biotechnol. 8, 93-98.
33. Pace, C. N. (1986) Methods Enzymol. 131, 266-289.
34. Ramm, K., and Plückthun, A. (1999) J. Mol Biol. (in press).
35. Young, N. M., MacKenzie, C. R., Narang, S. A., Oomen, R. P., and Baenziger, J. E. (1995) FEBS Lett. 377, 135-139.
36. Fink, A. L. (1998) Folding Des. 3, R9-23.
37. Mitraki, A., and King, J. (1989) Biotechnology 7, 690-697.
38. Wetzel, R. (1996) Cell 86, 699-702.
39. Wetzel, R. (1992) in Protein Engineering, A Practical Approach (Rees, A. R., and Sternberg, M. J., Eds.) pp 191-219, IRL Press, Oxford University Press.
40. Kim, D., and Yu, M. H. (1996) Biochem. Biophys. Res. Commun. 226, 378-384.
41. Wetzel, R. (1994) Trends Biotechnol. 12, 193-198.