A Transcriptionally Inactive E2F-1 Targets the MDM Family of Proteins for Proteolytic Degradation

Journal of Biological Chemistry

Volumn 276, Issue 49, 2001, Pages 45677-45685

  Strachan, Gordon D ^b   Rallapalli, Ravikumar ^b   Pucci, Bruna ^b   Lafond, Toulouse P ^b   Hall, David J ^a  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CELLS; MUTAGENESIS; YEAST;

APOPTOSIS;

PROTEINS;

BAFILOMYCIN A1; BINDING PROTEIN; LACTACYSTIN; MDM PROTEIN; MDMX S PROTEIN; N ACETYLLEUCYLLEUCYLMETHIONYLALANINE; N ACETYLLEUCYLLEUCYLNORLEUCYLALANINE; PROTEASOME; PROTEIN; PROTEIN MDM2; PROTEIN MDMX; PROTEINASE INHIBITOR; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F 1 [180-437]; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; MULTIENZYME COMPLEX; ONCOPROTEIN; PRIMER DNA; PROTO ONCOGENE PROTEINS;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CONTROLLED STUDY; DELETION MUTANT; DNA BINDING DOMAIN; HUMAN; HUMAN CELL; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; RETINOBLASTOMA PROTEIN BINDING DOMAIN; TRANSCRIPTION REGULATION; CELL LINE; GENETIC TRANSCRIPTION; GENETICS; HYDROLYSIS; METABOLISM; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS; TWO HYBRID SYSTEM;

BASE SEQUENCE; CELL LINE; CYSTEINE ENDOPEPTIDASES; DNA PRIMERS; HUMAN; HYDROLYSIS; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTO-ONCOGENE PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0035824686     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103765200     Document Type: Article

References (47)

1. Bandara, L. R., Buck, V. M., Zamanian, M., Johnston, L. H., and La Thangue, N. B. (1993) EMBO J. 12, 4317-4324
2. La Thangue, N. B. (1994) Curr. Opin. Cell Biol. 6, 443-450
3. Nevins, J. R., Leone, G., DeGregori, J., and Jakoi, L. (1997) J. Cell. Physiol. 173, 233-236
4. Horowitz, J. M. (1993) Genes Chromosomes Cancer (1993) 6, 124-131
5. Dyson, N. (1998) Genes Dev. 12, 2245-2262
6. DeGregori, J., Leone, G., Miron, A., Jakoi, L., and Nevins, J. R. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7245-7250
7. Phillips, A. C., Ernst, M. K., Bates, S., Rice, N. R., and Vousden, K. H. (1999) Mol. Cell 4, 771-781
8. Wu, X., and Levine, A. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 3602-3606
9. Phillips, A. C., Bates, S., Ryan, K. M., Helin, K., and Vousden, K. H. (1997) Genes Dev. 11, 1853-1863
10. Irwin, M., Marin, M. C., Phillips, A. C., Seelan, R. S., Smith, D. I., Liu, W., Flores, E. R., Tsai, K. Y., Jacks, T., Vousden, K. H., and Kaelin, W. G., Jr. (2000) Nature 407, 645-648
11. Lissy, N. A., Davis, P. K., Irwin, M., Kaelin, W. G., and Dowdy, S. F. (2000) Nature 407, 642-645
12. Zhu, J., Jiang, J., Zhou, W., and Chen, X. (1998) Cancer Res. 58, 5061-5065
13. Kowalik, T. F., DeGregori, J., Leone, G., Jakoi, L., and Nevins, J. R. (1998) Cell Growth Differ. 9, 113-118
14. Bates, S., Phillips, A. C., Clark, P. A., Stott, F., Peters, G., Ludwig, R. L., and Vousden, K. H. (1998) Nature 395, 124-125
15. Sherr, C. J., and Weber, J. D. (2000) Curr. Opin. Genet. Dev. 10, 94-99
16. Martin, K., Trouche, D., Hagemeier, C., Sorensen, T. S., La Thangue, N. B., and Kouzarides, T. (1995) Nature 375, 691-694
17. Xiao, Z. X., Chen, J., Levine, A. J., Modjtahedi, N., Xing, J., Sellers, W. R., and Livingston, D. M. (1995) Nature 375, 694-698
18. Loughran, O., and La Thangue, N. B. (2000) Mol. Cell. Biol. 20, 2186-2197
19. Momand, J., and Zambetti, G. P. (1997) J. Cell. Biochem. 64, 343-352
20. Thut, C. J., Goodrich, J. A., and Tjian, R. (1997) Genes Dev. 11, 1974-1986
21. Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., and Pavletich, N. P. (1996) Science 274, 948-953
22. Fang, S., Jensen, J. P., Ludwig, R. L., Vousden, K. H., and Weissman, A. M. (2000) J. Biol. Chem. 275, 8945-8951
23. Honda, R., and Yasuda, H. (2000) Oncogene 19, 1473-1476
24. Finlay, C. A. (1993) Mol. Cell. Biol. 13, 301-306
25. Flores, C., and Sobrevia, L. (2000) Rev. Med. Chile 128, 539-546
26. Shvarts, A., Bazuine, M., Dekker, P., Ramos, Y. F., Steegenga, W. T., Merckx, G., van Ham, R. C., van der Houven van Oordt, W., van der Eb, A. J., and Jochemsen, A. G. (1997) Genomics 43, 34-42
27. Shvarts, A., Steegenga, W. T., Riteco, N., van Laar, T., Dekker, P., Bazuine, M., van Ham, R. C., van der Houven van Oordt, W., Hateboer, G., van der Eb, A. J., and Jochemsen, A. G. (1996) EMBO J. 15, 5349-5357
28. Bottger, V., Bottger, A., Garcia-Echeverria, C., Ramos, Y. F., van der Eb, A. J., Jochemsen, A. G., and Lane, D. P. (1999) Oncogene 18, 189-199
29. Jackson, M. W., and Berberich, S. J. (2000) Mol. Cell. Biol. 20, 1001-1007
30. Tanimura, S., Ohtsuka, S., Mitsui, K., Shirouza, K., Yoshimura, A., and Ohtsubo, M. (1999) FEBS Lett. 447, 5-9
31. Sharp, D. A., Kratowicz, S. A., Sank, M. J., and George, D. L. (1999) J. Biol. Chem. 274, 38189-38196
32. Izzo, M. W., Strachan, G. D., Stubbs, M. C., and Hall, D. J. (1999) J. Biol. Chem. 274, 19498-19506
33. Rallapalli, R., Strachan, G., Cho, B., Mercer, W. E., and Hall, D. J. (1999) J. Biol. Chem. 274, 8299-8308
34. Pyrc, J. J., Moberg, K. H., and Hall, D. J. (1992) Biochemistry 31, 4102-4110
35. Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Cell 78, 761-771
36. Fenteany, G., and Schreiber, S. L. (1998) J. Biol. Chem. 273, 8545-8548
37. Inoue, S., Bar-Nun, S., Roitelman, J., and Simoni, R.D. (1991) J. Biol. Chem. 266, 13311-13317
38. Oda, K., Nishimura, Y., Ikehara, Y., and Kato, K. (1991) Biochem. Biophys. Res. Commun. 178, 369-377
39. Craighead, M. W., Tiwari, P., Keynes, R. G., and Waters, C. M. (1999) J. Neurosci. Res. 57, 236-243
40. Wang, K. K., Nath, R., Posner, A., Raser, K. J., Buroker-Kilgore, M., Hajimohammadreza, I., Probert, A. W., Marcoux, F. W., Ye, Q., Takano, E., Hatanaka, M., Maki, M., Caner, H., Collins, J. L., Fergus, A., Lee, K. S., Lunney, E. A., Hays, S. J., and Yuen, P. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 6687-6692
41. Jordan, K. L., Haas, A. R., Logan, T. J., and Hall, D. J. (1994) Oncogene 9, 1177-1185
42. Xu, M., Sheppard, K. A., Peng, C. Y., Yee, A. S., and Piwnica-Worms, H. (1994) Mol. Cell. Biol. 14, 8420-8431
43. Shan, B., Durfee, T., and Lee, W. H. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 679-684
44. Flemington, E. K., Speck, S. H., and Kaelin, W. G., Jr. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6914-6918
45. Nishinaka, T., Fu, Y. H., Chen, L. I., Yokoyama, K., and Chiu, R. (1997) Biochim. Biophys. Acta 1351, 274-286
46. Blagosklonny, M. V., An, W. G., Melillo, G., Nguyen, P., Trepel, J. B., and Neckers, L. M. (1999) Oncogene 18, 6460-6468
47. Yang, H. L., Dong, Y. B., Elliot, M. J., Liu, T. J., Atienza, C., Stilwell, A., and McMasters, K. M. (1999) Clin. Cancer Res. 5, 2242-2250