Role of PI3-kinase in Bcl-X induction and apoptosis inhibition mediated by IL-3 or IGF-1 in Baf-3 cells

Cell Death and Differentiation

Volumn 6, Issue 3, 1999, Pages 290-296

  Leverrier, Yann ^a   Thomas, Joëlle ^a   Mathieu, Anne Laure ^a   Walter, Low ^b   Blanquier, Bariza ^a   Marvel, Jacqueline ^a  

^a UNIVERSITÉ DE LYON   (France)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Bcl X; Caspase; IL 3

Indexed keywords

CASPASE; INTERLEUKIN 3; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL X; SOMATOMEDIN C;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE INDUCTION; PRIORITY JOURNAL; PROTEIN INDUCTION;

EID: 0032970003     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400492     Document Type: Article

References (43)

1. Raff MC, Barres BA, Burne JF, Coles HS, Ishizaki Y and Jacobson MD (1993) Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262: 695-700
2. Hannun YA (1997) Apoptosis and the dilemma of cancer chemotherapy. Blood 89: 1845-1853
3. Cohen GM (1997) Caspases: the executioners of apoptosis. Biochem. J. 326: 1-16
4. Nicholson DW and Thornberry NA (1997) Caspases: killer proteases. Trends Biochem. Sci. 22: 299-306
5. Boldin MP, Goncharov TM, Goltsev YV and Wallach D (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85: 803-815
6. Enari M, Talanian RV, Wong WW and Nagata S (1996) Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380: 723-726
7. Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME and Dixit VM (1996) FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85: 817-827
8. Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Litwack G and Alnemri ES (1996) Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. Proc. Natl. Acad. Sci. USA 93: 14486-14491
9. Longthorne VL and Williams GT (1997) Caspase activity is required for commitment to Fas-mediated apoptosis. EMBO J. 16: 3805-3812
10. McCarthy NJ, Whyte MK, Gilbert CS and Evan GI (1997) Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell. Biol. 136: 215-227
11. Zou H, Henzel WJ, Liu X, Lutschg A and Wang X (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90: 405-413
12. Chinnaiyan AM, Chaudhary D, O'Rourk K, Koonin EV and Dixit VM (1997) Role of CED-4 in the activation of CED-3. Nature 388: 728-729
13. Chinnaiyan AM, O'Rourke K, Lane BR and Dixit VM (1997) Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275: 1122-1126
14. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES and Wang X (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479-489
15. Reed JC (1997) Double identity for proteins of the Bcl-2 family. Nature 387: 773-776
16. Minn AJ, Velez P, Schendel SL, Liang H, Muchmore SW, Fesik SW, Fill M and Thompson CB (1997) Bcl-xL forms an ion channel in synthetic lipid membranes. Nature 385: 353-357
17. Schendel SL, Xie Z, Montai MO, Matsuyama S, Montai M and Reed JC (1997) Channel formation by antiapoptotic protein Bcl-2. Proc. Natl. Acad. Sci. USA 94: 5113-5118
18. Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, Daugas E, Geuskens M and Kroemer G (1996) Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184: 1331-1341
19. Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT and Thompson CB (1997) Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91: 627-637
20. Wang HG, Rapp UR and Reed JC (1996) Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 87: 629-638
21. Ahmed NN, Grimes HL, Bellacosa A, Chan TO and Tsichlis PN (1997) Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA 94: 3627-3632
22. Franke TF, Kaplan DR and Cantley LC (1997) PI3K: downstream AKTion blocks apoptosis. Cell 88: 435-437
23. Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y and Greenberg ME (1997) Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91: 231-241
24. Zha J, Harada H, Yang E, Jockel J and Korsmeyer SJ (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-XL. Cell 87: 619-628
25. Diaz-Meco MT, Municio MM, Frutos S, Sanchez P, Lozano J, Sanz L and Moscat J (1996) The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86: 777-786
26. Fukada T, Hibi M, Yamanaka Y, Takahashi-Tezuka M, Fujitani Y, Yamaguchi T, Nakajima K and Hirano T (1996) Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity 5: 449-460
27. Gotoh N, Tojo A and Shibuya M (1996) A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3. EMBO J. 15: 6197-6204
28. Kinoshita T, Yokota T, Arai K and Miyajima A (1995) Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J. 14: 266-275
29. Leverrier Y, Thomas J, Perkins GR, Mangeney M, Collins MK and Marvel J (1997) In bone marrow derived Baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways. Oncogene 14: 425-430
30. Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR and Greenberg ME (1997) Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275: 661-665
31. Kulik G, Klippel A and Weber MJ (1997) Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol. 17: 1595-1606
32. Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT and Nicholson DW (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272: 17907-17911
33. Furlong IJ, Ascaso R, Lopez Rivas A and Collins MK (1997) Intracellular acidification induces apoptosis by stimulating ICE-like protease activity. J. Cell Sci. 110: 653-661
34. Collette Y, Razanajaona D, Ghiotto M and Olive D (1997) CD28 can promote T cell survival through a phosphatidylinositol 3-kinase-independent mechanism. Eur. J. Immunol. 27: 3283-3289
35. Gonzalez-Garcia A, Merida I, Martinez AC and Carrera AC (1997) Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 272: 10220-10226
36. del Peso L, Gonzalez-Garcia M, Page C, Herrera R and Nunez G (1997) Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 278: 687-689
37. Minshall C, Arkins S, Freund GG and Kelley KW (1996) Requirement for phosphatidylinositol 3′-kinase to protect hemopoietic progenitors against apoptosis depends upon the extracellular survival factor. J. Immunol. 156: 939-947
38. Ito T, Deng X, Carr B and May WS (1997) Bcl-2 phosphorylation required for anti-apoptosis function. J. Biol. Chem. 272: 11671-11673
39. Sugimoto A, Friesen PD and Rothman JH (1994) Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans. EMBO J. 13: 2023-2028
40. White K, Tahaoglu E and Steller H (1996) Cell killing by the Drosophila gene reaper. Science 271: 805-807
41. Rodriguez-Tarduchy G, Collins M and Lopez-Rivas A (1990) Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores. EMBO J. 9: 2997-3002
42. Thomas J, Leverrier Y and Marvel J (1998) Bcl-X is the major pleiotropic anti-apoptotic gene activated by retroviral insertion mutagenesis in an IL-3 dependent bone marrow derived cell line. Oncogene 16: 1399-1408
43. Harrington EA, Bennett MR, Fanidi A and Evan Gl (1994) c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13: 3286-3295