-
1
-
-
0035969964
-
Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis
-
(2001)
Biochemistry
, vol.40
, pp. 853-860
-
-
Fedorov, A.1
Shi, W.2
Kicska, G.3
Fedorov, E.4
Tyler, P.C.5
Furneaux, R.H.6
Hanson, J.C.7
Gainsford, G.J.8
Larese, J.Z.9
Schramm, V.L.10
Almo, S.C.11
-
2
-
-
0035902502
-
Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces
-
(2001)
Biochemistry
, vol.40
, pp. 8204-8215
-
-
Shi, W.1
Basso, L.A.2
Santos, D.S.3
Tyler, P.C.4
Furneaux, R.H.5
Blanchard, J.S.6
Almo, S.C.7
Schramm, V.L.8
-
3
-
-
0033519996
-
The 2.0 Å structure of malarial purine phosphoribosyltransferase in complex with a transition-state analog inhibitor
-
(1999)
Biochemistry
, vol.38
, pp. 9872-9880
-
-
Shi, W.1
Li, C.M.2
Tyler, P.C.3
Furneaux, R.H.4
Cahill, S.M.5
Girvin, M.E.6
Grubmeyer, C.7
Schramm, V.L.8
Almo, S.C.9
-
8
-
-
0034700259
-
Kinetic isotope effect studies of the reaction catalyzed by uracil DNA glycosylase: Evidence for an oxocarbenium ion-uracil anion intermediate
-
(2000)
Biochemistry
, vol.39
, pp. 14054-14064
-
-
Werner, R.M.1
Stivers, J.T.2
-
20
-
-
84881454506
-
-
Pittsburgh, PA: Gaussian Inc.
-
(1998)
Gaussian 98, Revision A.6
-
-
Frisch, M.J.1
Trucks, G.W.2
Schlegel, H.B.3
Scuseria, G.E.4
Robb, M.A.5
Cheeseman, J.R.6
Zakrzewski, V.G.7
Montgomery, J.A.8
Stratman, R.E.9
Burant, J.C.10
-
23
-
-
0000124054
-
Immunodeficiency diseases caused by adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency
-
Edited by Scriver CR, Beaudet AL, Sly WS, Vallee D, Childs B, Kinzler KW, Vogelstein B. New York: McGraw-Hill
-
(2001)
The Metabolic & Molecular Bases of Inherited Disease, edn 8
, vol.11
, pp. 2585-2625
-
-
Hershfield, M.S.1
Mitchell, B.S.2
-
25
-
-
0035836674
-
Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4593-4598
-
-
Kicska, G.A.1
Long, L.2
Hörig, H.3
Fairchild, C.4
Tyler, P.C.5
Furneaux, R.H.6
Schramm, V.L.7
Kaufman, H.L.8
-
26
-
-
0035026893
-
Purine nucleoside phosphorylase inhibitor BCX-1777 (immucillin-H) - A novel potent and orally active immunosuppressive agent
-
(2001)
Int Immunopharm
, vol.1
, pp. 1199-1210
-
-
Bantia, S.1
Miller, P.J.2
Parker, C.D.3
Ananth, S.L.4
Horn, L.L.5
Kilpatrick, J.M.6
Morris, P.E.7
Hutchison, T.L.8
Montgomery, J.A.9
Sandhu, J.S.10
-
27
-
-
0028932756
-
Pre-steady state transition state analysis of the hydrolytic reaction catalyzed by purine nucleoside phosphorylase
-
(1995)
Biochemistry
, vol.34
, pp. 1153-1162
-
-
Kline, P.C.1
Schramm, V.L.2
-
31
-
-
0000544518
-
Lesch-Nyhan disease and its variants
-
Edited by Scriver CR, Beaudet AL, Sly WS, Vallee D, Childs B, Kinzler KW, Vogelstein B. New York: McGraw-Hill
-
(2001)
The Metabolic & Molecular Bases of Inherited Disease, edn 8
, vol.11
, pp. 2537-2570
-
-
Jinnah, H.A.1
Friedmann, T.2
-
33
-
-
0033017467
-
Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases
-
(1999)
Nat Struct Biol
, vol.6
, pp. 582-587
-
-
Li, C.M.1
Tyler, P.C.2
Furneaux, R.H.3
Kicska, G.4
Xu, Y.5
Grubmeyer, C.6
Girvin, M.E.7
Schramm, V.L.8
-
40
-
-
0002352018
-
Insights from heavy-atom isotope effects on phosphoryl and thiophosphoryl transfer reactions
-
Edited by Frey PA, Northrop DB. Washington DC: IOS press
-
(1999)
Enzymatic Mechanisms
, pp. 72-84
-
-
Hengge, A.C.1
-
43
-
-
0001900140
-
18O isotope effects to study acyl and phosphoryl transfer
-
Edited by Frey PA, Northrop DB. Washington DC: IOS Press
-
(1999)
Enzymatic Mechanisms
, pp. 8-19
-
-
Cleland, W.W.1
-
48
-
-
0028092999
-
Electrostatic potential surfaces of the transition state for AMP deaminase and for (R)-coformycin, a transition state inhibitor
-
(1994)
J Biol Chem
, vol.269
, pp. 22385-22390
-
-
Kline, P.C.1
Schramm, V.L.2
-
49
-
-
0034663824
-
Temperature effects on the catalytic efficiency, rate enhancement, and transition state affinity of cytidine deaminase, and the thermodynamic consequences for catalysis of removing a substrate 'anchor'
-
(2000)
Biochemistry
, vol.39
, pp. 9746-9753
-
-
Snider, M.J.1
Gaunitz, S.2
Ridgway, C.3
Short, S.A.4
Wolfenden, R.5
-
50
-
-
0001358095
-
Complete kinetic isotope effect description of transition states for acid-catalyzed hydrolyses of methyl α- and D-glucopyranosides
-
(1986)
J Am Chem Soc
, vol.108
, pp. 7287-7294
-
-
Bennet, A.J.1
Sinnott, M.L.2
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