Correlated conformational fluctuations during enzymatic catalysis: Implications for catalytic rate enhancement

Protein Science

Volumn 10, Issue 7, 2001, Pages 1319-1330

  Alper, Kutay O ^a   Singla, Manish ^a   Stone, Jennifer L ^a   Bagdassarian, Carey K ^a  

^a Dept of Economics and Thomas Jefferson Program in Public Policy at the College of William and Mary   (United States)

Author keywords

Catalysis; Conformational fluctuations; Cytidine deaminase; Kohonen neural network; Potential energy fluctuations

Indexed keywords

CYTIDINE DEAMINASE;

ARTICLE; ARTIFICIAL NEURAL NETWORK; CATALYSIS; CATALYST; CONFORMATIONAL TRANSITION; CORRELATION FUNCTION; ENERGY TRANSFER; ENZYME CONFORMATION; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL; REACTION ANALYSIS;

ALGORITHMS; ANIMALS; CATALYSIS; CYTIDINE DEAMINASE; ENZYMES; HUMANS; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION; THERMODYNAMICS; VIBRATION;

EID: 0034978909     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.220101     Document Type: Article

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