Approaching the transition state in the crystal structure of a phosphoribosyltransferase

Biochemistry

Volumn 37, Issue 49, 1998, Pages 17120-17127

  Focia, Pamela J ^a   Craig III, Sydney P ^a   Eakin, Ann E ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; CHAGAS DISEASE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME STRUCTURE; GENE MUTATION; GOUT; LESCH NYHAN SYNDROME; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA CRUZI;

ANIMALS; BINDING SITES; CATIONS, DIVALENT; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LIGANDS; MAGNESIUM; MANGANESE; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; TRYPANOSOMA CRUZI;

PROTOZOA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0032497936     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9821465     Document Type: Article

References (12)

1. Garcia-Zapata, M. T. A., McGreevy P. B. and Marsden, P. D. (1991) in Hunter's Tropical Medicine (Strickland, G. T., Ed.) pp 628-637, W. B. Saunders, Philadelphia.
2. Berens, R. L., Krug, E. C., and Marr, J. J. (1995) in Biochemistry and Molecular Biology of Parasites (Marr, J. J., and Müller, M. Eds.) pp 89-117, Academic Press Inc., San Diego.
3. Craig, S. P., III, and Eakin, A. E. (1997) Parasitol. Today 13, 238-241.
4. Sculley, D. G., Dawson, P. A., Emmerson, B. T., and Gordon, R. B. (1992) Hum. Genet. 90, 195-207.
5. Eads, J. C., Ozturk, D., Wexler, T. B., Grubrneyer, C., and Sacchettini, J. C. (1997) Structure 5, 47-58.
6. Smith, J. L. (1995) Curr. Opin. Struct. Biol. 5, 752-757.
7. Yuan, L., Craig, S. P., III, McKerrow, J. H., and Wang, C. C. (1992) Biochemistry 31, 806-810.
8. Xu, Y., Eads, J., Sacchettini, J. C., and Grubmeyer, C. (1997) Biochemistry 36, 3700-3712.
9. Munagala, N. R., Chin, M. S., and Wang, C. C. (1998) Biochemistry 37, 4045-4051.
10. Goitein, R. K., Chelsky, D., and Parsons, S. M. (1978) J. Biol. Chem. 253, 2963-2911.
11. Bhatia, M. B., and Grubmeyer, C. (1993) Arch. Biochem. Biophys. 303, 321-325.
12. Tao, W., Grubmeyer, C., and Blanchard, J. S. (1996) Biochemistry 35, 14-21.