Effects on general acid catalysis from mutations of the invariant tryptophan and arginine residues in the protein tyrosine phosphatase from Yersinia

Biochemistry

Volumn 39, Issue 1, 2000, Pages 46-54

  Hoff, Richard H ^a   Hengge, Alvan C ^a   Wu, Li ^b   Keng, Yen Fang ^b   Zhang, Zhong Yin ^b  

^a UTAH STATE UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENYL PHOSPHATE; ACID; ALANINE; ARGININE; ASPARTIC ACID; LYSINE; MUTANT PROTEIN; PHENYLALANINE; PROTEIN TYROSINE PHOSPHATASE; TRYPTOPHAN;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MICHAELIS MENTEN KINETICS; MUTATION; NONHUMAN; PRIORITY JOURNAL; YERSINIA;

ACIDS; ARGININE; CATALYSIS; HYDROGEN-ION CONCENTRATION; KINETICS; MUTAGENESIS, SITE-DIRECTED; NITROGEN ISOTOPES; NITROPHENOLS; OXYGEN ISOTOPES; PROTEIN-TYROSINE-PHOSPHATASE; PROTONS; SUBSTRATE SPECIFICITY; TRYPTOPHAN; YERSINIA;

EID: 0034635121     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991570i     Document Type: Article

References (31)

1. Zhang, Z.-Y. (1998) CRC Crit. Rev. Biochem. Mol. Biol. 33, 1-52.
2. Zhang, Z.-Y., Wang, Y., Wu, L., Fauman, E., Stuckey, J. A., Schubert, H. L., Saper, M. A., and Dixon, J. E. (1994) Biochemistry 33, 15266-15270.
3. Cho, H., Krishnaraj, R., Kitas, E., Bannwarth, W., Walsh, C. T., and Anderson, K. S. (1992) J. Am. Chem. Soc. 114, 7296-7298.
4. Guan, K. L., and Dixon, J. E. (1990) Science 249, 553-556.
5. Zhang, Z.-Y., Wang, Y., and Dixon, J. E. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 1624-1627.
6. Stuckey, J. A., Schubert, H. L., Fauman, E. B., Zhang, Z.-Y., Dixon, J. E., and Saper, M. A. (1994) Nature 370, 571-575.
7. Schubert, H. L., Fauman, E. B., Stuckey, J. A., Dixon, J. E., and Saper, M. A. (1995) Protein Sci. 4, 1904-1913.
8. Keng, Y.-F., Wu, L., and Zhang, Z.-Y. (1999) Eur. J. Biochem. 259, 809-814.
9. Hengge, A. C., Sowa, G. A., Wu, L., and Zhang, Z.-Y. (1995) Biochemistry 34, 13982-13987.
10. Hengge, A. C., Denu, J. M., and Dixon, J. E. (1996) Biochemistry 35, 7084-7092.
11. Hengge, A. C., Zhao, Y., Wu, L., and Zhang, Z.-Y. (1997) Biochemistry 36, 7928-7936.
12. Hengge, A. C., Edens, W. A., and Elsing, H. (1994) J. Am. Chem. Soc. 116, 5045-5049.
13. Bourne, N., and Williams, A. (1984) J. Org. Chem. 49, 1200-1204.
14. Bigeleisen, J., and Wolfsberg, M. (1958) Adv. Chem. Phys. 1, 15-76.
15. O'Leary, M. H., and Marlier, J. F. (1979) J. Am. Chem. Soc. 101, 3300-3306.
16. Caldwell, S. R., Raushel, F. M., Weiss, P. M., and Cleland, W. W. (1991) Biochemistry 30, 7444-7450.
17. Wu, L., and Zhang, Z.-Y. (1996) Biochemistry 35, 5426-5434.
18. Zhang, Z.-Y., Malochowski, W. P., Van Etten, R. L., and Dixon, J. E. (1994) J. Biol. Chem. 269, 8140-8145.
19. Northrop, D. B. (1977) in Isotope Effects on Enzyme-Catalyzed Reactions (Cleland, W. W., O'Leary, M. H., and Northrop, D. B., Eds.) p 122, University Park Press, Baltimore, MD.
20. Massoud, S. S., and Sigel, H. (1988) Inorg. Chem. 27, 1447-1453.
21. Knight, W. B., Weiss, P. M., and Cleland, W. W. (1986) J. Am. Chem. Soc. 108, 2759-2761.
22. Hengge, A. C., and Cleland, W. W. (1990) J. Am. Chem. Soc. 112, 7421-7422.
23. Thatcher, G. R. J., and Kluger, R. (1989) Adv. Phys. Org. Chem. 25, 99-265.
24. Hengge, A. C. (1998) in Comprehensive Biological Catalysis: A Mechanistic Reference (Sinnott, M., Ed.) pp 517-542, Academic Press, San Diego, CA.
25. Hengge, A. C., and Hess, R. A. (1994) J. Am. Chem. Soc. 116, 11256-11263.
26. Weiss, P. M., Knight, W. B., and Cleland, W. W. (1986) J. Am. Chem. Soc. 108, 2761-2762.
27. Hengge, A. C., and Cleland, W. W. (1991) J. Am. Chem. Soc. 113, 5835-5841.
28. Hengge, A. C., Tobin, A. E., and Cleland, W. W. (1995) J. Am. Chem. Soc. 117, 5919-5926.
29. Hoff, R. H., Wu, L., Zhou, B., Zhang, Z.-Y., and Hengge, A. C. (1999) J. Am. Chem. Soc. 121, 9514-9521.
30. Alhambra, C., Wu, L., Zhang, Z.-Y., and Gao, J. (1998) J. Am. Chem. Soc. 120, 3858-3866.
31. Fauman, E. B., Yuvaniyama, C., Schubert, H., Stuckey, J. A., and Saper, M. A. (1996) J. Biol. Chem. 217, 18780-18788.