Pathology of lymphoma progression

Histopathology

Volumn 38, Issue 4, 2001, Pages 285-306

  Muller Hermelink H K ^a   Zettl, A ^a   Pfeifer, W ^a   Ott, G ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

B cell lymphoma; Lymphoma; Progression; T cell lymphoma; Transformation

Indexed keywords

B CELL LYMPHOMA; CANCER GROWTH; CARCINOGENESIS; CELL PROLIFERATION; CLONAL VARIATION; DISEASE COURSE; GENETIC TRAIT; HODGKIN DISEASE; HUMAN; LYMPHOMA; NONHODGKIN LYMPHOMA; PHENOTYPE; PRIORITY JOURNAL; REVIEW;

EID: 0035569972     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.2001.01120.x     Document Type: Review

References (156)

1. The hallmarks of cancer
2. A revised European-American Classification of lymphoid neoplasms: A proposal from the international lymphoma study group
3. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: Report of the clinical advisory committee meeting - Arlie House, Virginia, November, 1997
4. High-grade transformation of low-grade non-Hodgkin's lymphomas: Mechanisms of tumor progression
5. Tumor progression in malignant lymphoma
6. The experimental study of tumor progression: A review
7. Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukemia
8. Pitfalls in the diagnosis of lymphoma and leukemia from a pathologist's point of view
9. Composite lymphoma
10. Composite lymphoma and related disorders
11. Follicular lymphoma - A reevaluation of its position in the scheme of malignant lymphoma based on a survey of 253 cases
12. An autopsy study of histologic progression in non-Hodgkin's lymphomas
13. Mantle cell lymphoma: Natural history defined in a serially biopsied population over a 20-year period
14. Prolymphocytic transformation of chronic lymphocytic leukemia
15. Prolymphocytoid' transformation of chronic lymphocytic leukemia
16. Blastic transformation of mantle cell lymphoma: Genetic evidence for a clonal link between the two stages of the tumour
17. Clonal evolution of B cells in transformation from low- to high-grade lymphoma
18. Molecular genetic demonstration of the diverse evolution of Richter's syndrome
19. B-cell lymphoma after angioimmunoblastic lymphadenopathy: A case with oligoclonal gene rearrangements associated with Epstein-Barr virus
20. Development of Epstein-Barr virus-associated B-cell lymphoma after intensive treatment of patients with angioimmunoblastic lymphadenopathy with dysproteinemia
21. Epstein-Barr virus genome carrying monoclonal B-cell lymphoma in a patient with adult T-cell leukemia-lymphoma
22. Epstein-Barr virus associated B-cell proliferation and B-cell non Hodgkin's lymphoma in patients with T-cell NHL
23. Histologically discordant lymphomas with B-cell and T-cell components
24. Small B-cell lymphoid neoplasms with coexisting T-cell lymphomas
25. Composite B-cell and T-cell lymphoma - Coincidental occurrence or related neoplasms?
26. Simultaneous phenotypically distinct but clonally identical mucosa-associated lymphoid tissue and follicular lymphoma in a patient with Sjögren's syndrome
27. A distinctive composite lymphoma consisting of clonally related mantle cell lymphoma and follicle center lymphoma
28. High-grade non-Hodgkin lymphoma relapsing as low-grade follicular lymphoma: So-called downgrading
29. Diffuse large cell lymphoma with discordant bone marrow histology
30. The indespensable role of micro-environment in the natural history of low-grade B-cell neoplasms
31. Genetic relatedness of lymphoid malignancies
32. The t(11;18) (q21;q21) chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin's lymphomas of mucosa-associated lymphoid tissue (MALT-) type
33. Exclusive detection of the t(11;18) (q21;q21) in extranodal marginal zone B cell lymphomas (MZBL) of MALT type in contrast to other MZBL and extranodal large B cell lymphomas
34. The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation
35. IgV gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
36. Unmutated IgVH genes are associated with a more aggressive form of chronic lymphocytic leukemia
37. The natural history of nodular lymphoma
38. Non-Hodgkin's lymphoma - A study of the evolution of the disease based upon 92 autopsied cases
39. Histological transformation of non-Hodgkin's lymphoma
40. Histologic progression in non-Hodgkin's lymphoma
41. Histologic conversion in the non-Hodgkin's lymphomas
42. Malignant lymphomas of follicular center cell origin in humans
43. The natural history of initially untreated low-grade non-Hodgkin's lymphomas
44. Follicular low-grade non-Hodgkin's lymphoma: Long-term outcome with or without tumour progression
45. Incidence, predictive factors, and outcome of lymphoma transformation in follicular lymphoma patients
46. Transformation of follicular lymphoma into CD30-large cell lymphoma with anaplastic cytologic features
47. Paraimmunoblastic variant of small lymphocytic lymphoma/leukemia
48. Malignant lymphoma supervening in chronic lymphocytic leukemia and related disorders
49. Hodgkin's disease variant of Richter's syndrome
50. Chronic lymphocytic leukemia with coexistent Hodgkin's disease
51. Chronic lymphocytic leukemia/small lymphocytic lymphoma with Reed-Sternberg-like cells and possible transformation to Hodgkin's disease
52. Origin of the Hodgkin/Reed-Sternberg cells in chronic lymphocytic leukemia with 'Hodgkin's transformation'
53. Hodgkin and Reed-Sternberg-like cells in B-cell chronic lymphocytic leukemia represent the outgrowth of single germinal-center B-cell-derived clones: Potential precursors of Hodgkin and Reed-Sternberg cells in Hodgkin's disease
54. Associated chronic lymphocytic leukemia and multiple myeloma: Origin from a single clone
55. Molecular evidence for a single clonal origin in biphenotypic concomitant chronic lymphocytic leukemia and multiple myeloma
56. Chronic lymphocytic leukemia terminating in acute leukemia
57. Simultaneously increased expression of c-myc and mu chain genes in acute blastic transformation of a chronic lymphocytic leukemia
58. Blast crisis supervening on chronic lymphocytic leukemia. A monoclonal progression of the disease as defined by cell surface markers
59. Chronic lymphocytic leukemia in (Richter's) transformation
60. Second cancers following non-Hodgkin's lymphoma
61. B-chronic lymphocytic leukemia, small lymphocytic lymphoma, and lymphoplasmacytic lymphoma, including Waldenström's macroglobulinemia: A clinical, morphologic, and biologic spectrum of similar disorders
62. Relationship between Hodgkin's disease and Non-Hodgkin's lymphomas
63. Activation of the c-myc oncogene in a precursor B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma
64. Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma
65. Clinical, morphological, and cytogenetic characteristics of patients with lymphoid malignancies charcterized by both t(14;18) (q32;q21) and t(8;14) (q24;q32) or t(8;22) (q24;qll)
66. Precursor B-lymphoblastic transformation of grade I follicle center lymphoma
67. Blastic/blastoid transformation of follicular lymphoma
68. Composite lymphoma - A clinicopathologic analysis of nine patients with Hodgkin's disease and B-cell non-Hodgkin's lymphoma
69. Epstein-Barr virus is infrequently identified in non-Hodgkin's lymphomas associated with Hodgkin's disease
70. The bcl-2 oncogene in Hodgkin's disease arising in the setting of follicular lymphoma
71. Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's lymphoma
72. Histologic transformation of follicular lymphoma to diffuse lymphoma represents tumor progression by a single malignant B cell
73. Morphologic transformation of follicular lymphoma is associated with somatic mutation of the translocated bcl-2 gene
74. High-grade transformation of chronic lymphocytic leukemia and low-grade non-Hodgkin's lymphoma. Genotypic confirmation of clonal identity
75. Relationship between highgrade lymphoma and low-grade B-cell mucosa-associated lymphoid tissue lymphoma (MALToma) of the stomach
76. Low grade gastric B-cell MALT lymphoma progressing into high grade lymphoma. Clonal identity of the two stages of the tumour, unusual bone involvement and leukemic dissemination
77. Genetic evidence for a clonal link between low and high-grade components in gastric MALT B-cell lymphoma
78. Distinct clonal origin of low-grade MALT-type and high-grade lesions of a multifocal gastric lymphoma
79. Marginal zone B-cell lymphoma: A clinical comparison of nodal and mucosa-associated lymphoid tissue types
80. Nodal monocytoid B-cell lymphoma
81. Splenic lymphoma with circulating villous lymphocytes/Splenic marginal-zone lymphoma
82. Blastic transformation of splenic marginal zone B-cell lymphoma
83. The histogenesis of large-cell gastric lymphomas
84. Hodgkin's disease and an extranodal marginal zone B-cell lymphoma in the small intestine: An unusual composite lymphoma
85. Mantle cell lymphoma: A clinicopathologic study in 80 cases
86. p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas
87. Mantle-cell lymphoma
88. 'Composite' lymphoma, lymphoplasmacytoid and diffuse large B-cell lymphoma of the spleen: Molecular-genetic evidence of a common clonal origin
89. Diffuse large cell lymphoma in a patient with hairy cell leukemia: Immunoglobulin gene analysis reveals separate clonal origins
90. Hodgkin's disease in hairy cell leukemia: Phenotypic characterization of neoplastic cells
91. Identification of genetic lesions associated with diffuse large-cell lymphoma
92. Variation in the clinical course of adult T-cell leukemia
93. Diagnostic criteria and classification of clinical subtypes of adult T-cell leukemia-lymphoma. A report from the Lymphoma Study Group 1984-87
94. The pathologic spectrum of adult T-cell leukemia/lymphoma in United States
95. Transformation of cutaneous T-cell lymphoma to large cell lymphoma: A clinicopathologic and immunologic study
96. Clinicopathologic and immunologic features associated with transformation of mycosis fungoides to large-cell lymphoma
97. Transformation of mycosis fungoides/Sezary syndrome: Clinical characteristics and prognosis
98. Transformation of mycosis fungoides: Clinicopathologic and prognostic features of 45 cases
99. Transformation of mycosis fungoides: T-cell receptor beta gene analysis demonstrating a common clonal origin for plaque-type mycosis fungoides and CD30+ large-cell lymphoma
100. Proposals for the classification of chronic (mature) B and T lymphoid leukemias
101. The concept of typical and atypical chronic lymphocytic leukaemia
102. Lymph node histology in typical and atypical chronic lymphocytic leukemia
103. 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis
104. Deficiency of the ATM protein expression defines an aggressive subgroup of B-cell chronic lymphocytic leukemia
105. Somatic ATM mutations indicate a pathogenetic role of ATM in B-cell chronic lymphocytic leukemia
106. p53 gene deletions predicts for poor survival and non-response to therapy with purine analogues in chronic B-cell leukemias
107. p53 expression in B-cell chronic lymphocytic leukemia: A marker of disease progression and poor prognosis
108. Atypical chronic lymphocytic leukemia with t(11;14) (q13;q32): Karyotype evolution and prolymphocytic transformation
109. Cytogenetic and interphase cytogenetic characterization of atypical chronic lymphocytic leukemia carrying bcl-1 translocation
110. The relevance of cytological studies and Ki-67 reactivity to the clinical course of chronic lymphocytic leukemia
111. Correlation of trisomy 12 with proliferating cells by combined immunohistochemistry and fluorescence in situ hybridization in chronic lymphocytic leukemia
112. Prognostic value of cellular proliferation and histologic grade in follicular lymphoma
113. Cytogenetic and biological features define two types of follicular lymphomas grade 3
114. Follicular lymphoma: Do histologic subtypes predict outcome?
115. Follicular large-cell lymphoma: Intermediate or low-grade?
116. Follicular lymphoma: Assessment of prognostic factors in 127 patients followed for 10 years
117. Effect of degree of nodularity on the survival of patients with nodular lymphomas
118. Clinical significance of follicular lymphoma with monocytoid B-cells
119. Prognostic value of chromosomal abnormalities in follicular lymphoma
120. INK4a gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of Non-Hodgkin's lymphomas
121. p53 mutation is associated with progression in follicular lymphoma
122. Correlation of bcl-2 rearrangement with clinical characteristics and outcome in indolent follicular lymphoma
123. Histological grading in gastric lymphoma: Pretreatment criteria and clinical relevance
124. Histological grading with clinical relevance in gastric mucosa-associated lymphoid tissue (MALT) lymphoma
125. Translocation t(11;18) absent in early gastric marginal zone B-cell lymphoma of MALT type responding to eradication of Helicobacter pylori infection
126. Bcl-10 gene mutation in lymphoma
127. Splenic marginal zone lymphoma with increased number of blasts: An aggressive variant?
128. Poor prognosis in non-villous splenic marginal zone cell lymphoma is associated with p53 mutations
129. Increased number of chromosomal imbalances and high-level DNA amplifications in mantle cell lymphoma are associated with blastoid variants
130. Blastoid variants of mantle cell lymphoma: Frequent bcl-1 rearrangements at the major translocation cluster region and tetraploid chromosome clones
131. Deletions and loss of expression of pl6INK41 and p21WAF1 genes are associated with aggressive variants of mantle cell lymphoma
132. European Intergroup study of mantle cell lymphoma: Pathology, proliferation indices and survival
133. Molecular pathophysiology of indolent lymphoma
134. Cytogenetic changes in the progression of lymphoma
135. Cytogenetic evolution patterns in non-Hodgkin's lymphoma
136. Sequential analysis of 43 patients with non-Hodgkin's lymphoma: Clinical correlations with cytogenetic, histologic, immunophenotyping, and molecular studies
137. The accumulation of p53 abnormalities is associated with progression of mucosa-associated lymphoid tissue lymphoma
138. p53 mutations are associated with histologic transformation of follicular lymophoma
139. Mutations of the p53 gene in adult T-cell leukemia
140. p53 gene mutation and loss of heterozygosity are associated with increased risk of disease progression in adult T cell leukemia
141. Overexpression of p53 protein in cutaneous T cell lymphoma: Relationship to large cell transformation and disease progression
142. p53 overexpression as a marker of poor prognosis in mantle cell lymphomas with t(11;14) (q13;q32)
143. Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma
144. Loss of p16/INK4a protein expression in non-Hodgkin's lymphomas is a frequent finding associated with tumor progression
145. Codeletion of CDKN2 and MTAP genes in a subset of non-Hodgkin's lymphoma may be associated with histologic transformation from low-grade to diffuse large-cell lymphoma
146. Deletion analysis of the p16 tumor suppressor gene in gastrointestinal mucosa-associated lymphoid tissue lymphomas
147. Increasing methylation of the CDKN2A gene is associated with progression of adult T-cell leukemia
148. INK4a gene alterations are frequent in lesions of mycosis fungoides
149. c-myc gene abnormalities in mucosa-associated lymphoid tissue (MALT) lymphomas
150. c-myc rearrangements in histologically progressed follicular lymphomas
151. Somatic point mutations in the translocated bcl-2 genes of non-Hodgkin's lymphomas and lymphocytic leukemias: Implications for mechanisms of tumor progression
152. Nonimmunoglobulin gene hypermutation in germinal center B cells
153. Higher-grade transformation of follicle center lymphoma is associated with somatic mutation of the 5′noncoding regulatory region of the bcl-6 gene
154. Malignant lymphoma. A clinico-pathological survey of 618 cases
155. Blastic variant of hairy cell leukemia