Overexpression of p53 protein in cutaneous T cell lymphoma: Relationship to large cell transformation and disease progression

Journal of Investigative Dermatology

Volumn 110, Issue 5, 1998, Pages 767-770

  Li, G ^a   Chooback, L ^a   Wolfe, J T ^a   Rook, A H ^a   Felix, C A ^a   Lessin, S R ^a   Salhany, K E ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Mycosis fungoides; p53 gene mutations; Sezary syndrome

Indexed keywords

PROTEIN P53;

ARTICLE; CELL TRANSFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; LARGE CELL LYMPHOMA; MYCOSIS FUNGOIDES; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEZARY SYNDROME; SINGLE STRAND CONFORMATION POLYMORPHISM; SKIN BIOPSY; SKIN LYMPHOMA; T CELL LYMPHOMA; TUMOR SUPPRESSOR GENE;

EID: 0031899653     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00167.x     Document Type: Article

References (35)

1. D.J.A. Adamson W.D. Thompson A.A. Dawson B. Bennett N.E. Haites p53 mutation and expression in lymphoma Br J Cancer 72 1995 150 154
2. S. Ara P.S.Y. Lee M.F. Hansen H. Saya Codon 72 polymorphism of the TP53 gene Nucl Acids Res 18 1990 4961
3. S.L. Brice D. Krzemien W.L. Weston J.C. Huff Detection of herpes simplex virus DNA in cutaneous lesions of erythema multiforme J Invest Dermatol 93 1989 183 187
4. L. Cerroni E. Rieger S. Hödl H. Kerl Clinicopathologic and immunologic features associated with transformation of mycosis fungoides to large-cell lymphoma Am J Surg Pathol 16 1992 543 552
5. E. Cesarman G. Inghirami A. Chadburn D.M. Knowels High levels of p53 protein expression do not corrlate with p53 gene mutations in anaplastic large cell lymphoma Am J Pathol 143 1993 845 856
6. E. Dmitrovsky M.J. Mattews P.A. Bunn Cytologic transformation in cutaneous T cell lymphoma: A clinicopathologic entity associated with poor prognosis J Clin Oncol 5 1987 208 215
7. C.A. Felix D.L. Brown T. Mitsudomi Polymorphism at codon 36 of the p53 gene Oncogene 9 1994 327 328
8. S.A. Garatti E. Roscetti D. Trecca N.S. Fracchiolla A. Neri E. Berti bcl-1, bcl-2, p53, c-myc, and lyt-10 analysis in cutaneous lymphomas Recent Results in Cancer Research 139 1995 249 261
9. M.S. Greenblatt W.P. Bennett M. Holstein C.C. Harris Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogensis Cancer Res 54 1994 4855 4878
10. J.P. Greer K.E. Salhany L.E. King Cutaneous T cell lymphoma: mycosis fungoides and Sezary symdrome G.R. Lee 9th edn Clinical Hematology 1993 Lea and Febiger Philadelphia 2143 2169
11. N.L. Harris E.S. Jaffe H. Stein A revised European-American Classification of lymphiod neoplasms: A proposal from the international Lymphoma Study Group Blood 84 1994 1361 1392
12. J. Imamura I. Miyoshi H.P. Koeffler p53 in hematologic malignancies Blood 84 1994 2412 2421
13. P. Kanavaros D. Loannidou M. Tzardi G. Datseris J.G.D. Kanavaros A. Tosca Mycosis fungoides: expression of C-myc p62 p53, bcl-2 and PCNA proteins and absence of association with Epstein-Barr virus Path Res Pract 190 1994 767 774
14. J.E. Landers D.S. Haines Iiijf Strauss D.L. George Enhanced translation: A novel mechanism of mdm2 oncogene overexpression identified in human tumor cells Oncogene 9 1994 2745 2750
15. D.P. Lane On the expression of the p53 protein in human cancers Mol Biol Reports 19 1994 23 29
16. A.F. Lauritzen G.L. Vejlsgaard K. Hou-Jensen E. Ralfkiaer p53 protein expression in cutaneous T cell lymphomas Br J Dermatol 133 1995 32 36
17. C. Li C.D. O’Connell M. Beckwith D.L. Longo Detection of p53 mutations in B cell non-Hodgkin’s lymphoma cell lines Leukemia 9 1995 650 655
18. G. Li A.H. Rook K.E. Salhany A.H. Rook S.R. Lessin The pathogenesis of large cell transformation in cutaneous T cell lymphoma is not associated with t (2, 5) (p23; q35) chromosomal translocation J Cutan Pathol 24 1997 403 408
19. F. Lo Coco G. Gaidano D.C. Louie K. Offit p53 mutations are associated with histologic transformation of folicular lymphoma Blood 82 1993 2289 2295
20. S. Lutzker A. Levine A functionally inactive p53 protein in teratocarcinoma cells is activated either by DNA damage or cellular differentiation Nature Med 2 1996 804 810
21. D.I. Marks E.C. Vonderheid B.W. Kurz Analysis of p53 and mdm-2 expression in 18 patients with Sezary syndrome Br J Haematol 92 1996 890 899
22. J.M. McGregor E.A. Dublin D.A. Levison D.M. MacDonald N.P. Smith S. Whittaker p53 immunoreactivity is uncommon in primary cutaneous lymphoma Br J Dermatol 132 1995 353 358
23. R.F. de Misa J.M. Azana A. Harto C. Bellas A. Ledo Infrequent expression of protein p53 in epidermotropic variants of cutaneous T cell lymphoma J Dermatol 22 1995 524 526
24. T. Mitsudomi S.M. Steinberg M.M. Nau p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features Oncogene 7 1992 171 180
25. U.M. Moll A.G. Ostermeyer R. Haladay B. Winkfield M. Frazier G. Zambetti Ctyoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage Mol Cell Biol 16 1996 1126 1137
26. A. Neri N.S. Francchiolla E. Roscetti S. Gratti D. Trecca A. Boletini Molecular analysis of cutaneous B- and T cell lymphomas Blood 86 1995 3160 3172
27. J.D. Oliner K.W. Kinzler P.S. Melter D.L. George B. Vogelstein Amplification of a gene encoding a p53 associated protein in human sacromas Nature 358 1992 80 82
28. K.E. Salhany J.B. Cousar J.P. Greer T.T. Casey J.P. Fields R.D. Collins Transformation of cutaneous T cell lymphoma to large cell lymphoma: a clinicopathologic and immunologic study Am J Pathol 132 1988 265 277
29. C.A. Sander T. Yano H.M. Clark C. Harris D.L. Longo E.S. Jaffe M. Raffeld p53 mutation is associated with progression in follicular lymphomas Blood 82 1993 1994 2004
30. F. Sanger S. Nicklens A.R. Coulson DNA sequencing with chain termination inhibitors Proc Natl Acad Sci 74 1977 5463 5467
31. E.A. Strauss M.R. Hosler P. Herzog K. Salhany R. Louie C.A. Felix Complex replication error causes p53 mutation in Li-Fraumeni Family Cancer Res 55 1995 3237 3241
32. B. Vogelstein K.W. Kinzier p53 function and dysfunction Cell 70 1992 523 526
33. J.T. Wolfe L. Chooback D.T. Finn C. Jaworsky A.H. Rook S. Lessin Large cell transformation following detection of minimal residual disease in cutaneous T cell: Molecular and in-situ analysis of a single T cell clone expressing the identical T cell receptor J Clin Oncol 13 1995 1751 1757
34. G. Wood D. Bahler R. Hoppe Transformation of mycosis fungoides: T cell receptor β gene analysis demonstrates a common clonal origin for plaque-type mycosis fungoides and CD30+ large cell lymphoma J Invest Dermatol 101 1993 296 300
35. J.J. Yunis G. Frizzera M.M. Oken J. McKenna A. Theologides M. Arnesen Multiple recurrent genomic defects in folicullar lymphoma: A possible model for cancer N Engl J Med 316 1987 79 85