p53 Gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas

Blood

Volumn 87, Issue 8, 1996, Pages 3351-3359

  Hernandez, Luis ^b   Fest, Thierry ^b   Cazorla, Maite ^b   Teruya Fetdstein, Julie ^b   Bosch, Francesc ^b   Peinado, Miguel A ^b   Piris, Miguel A ^b   Montserrat, Emilio ^b   Cardesa, Antonio ^b   Jaffe, Elaine S ^b   Campo, Elías ^a   Raffeld, Mark ^b  

^a HOSPITAL CLÍNIC   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; PROTEIN P53;

ARTICLE; B CELL LYMPHOMA; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MISSENSE MUTATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

EID: 15844382913     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.8.3351.bloodjournal8783351     Document Type: Article

References (47)

1. Weisenburger DD, Sanger WG, Armitage JO, Purtilo DT: Intermediate lymphocytic lymphoma: Immunophenotypic and cytogenetic findings. Blood 69:1617, 1987
2. Vandenberghe E, de Wolf-Peters C, van den Oord J, Wlodarska I, Delabie J, Stul M, Thomas J, Michaux JL, Mecucci C, Cassiman JJ, van den Berghe H: Translocation (11;14): A cytogenetic anomaly associated with B-cell lymphomas of non-follicle centre cell lineage. J Pathol 163:13, 1991
3. Williams ME, Westermann CD, Swerdlow SH: Genotypic characterization of centrocytic lymphoma: Frequent rearrangement of the chromosome 11 bcl-1 locus. Blood 76:1387, 1990
4. Medeiros LJ, Van Krieken JH, Jaffe ES, Raffeld M: Association of bcl-1 rearrangements with lymphocytic lymphoma of intermediate differentiation. Blood 76:2086, 1990
5. Withers DA, Harvey RC, Faust JB, Malynk O, Carey K, Meeker TC: Characterization of a candidate bcl-1 gene. Mol Cell Biol 11:4846, 1991
6. Rosenberg CL, Wong E, Petty EM, Balf AE, Tsujimoto Y, Harris NL, Arnold A: PRAD1, a candidate BCL1 oncogene: Mapping and expression in centrocytic lymphoma. Proc Natl Acad Sci USA 88:9638, 1991
7. Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A: A novel cyclin encoded by BCL1-linked candidate oncogene. Nature 350:512, 1991
8. Rimokh R, Berger F, Delsol G, Charrin C, Bertheas MF, French M, Garoscio O, Felman P, Coiffier B, Bryon PA, Rochet M, Genthilhomme O, Germain D, Magaud JP: Rearrangement and overexpression of the BCL-1/PRAD-1 gene in intermediate lymphocytic lymphomas and in t(11q13)-bearing leukemias. Blood 81:3063, 1993
9. Oka K, Ohno T, Kita K, Yamaguchi M, Takakura N, Nishi K, Miwa H, Shirakawa S: PRAD-1 gene overexpression in mantle cell lymphoma but in not in other low grade B-cell lymphomas, including extranodal lymphoma. Br J Haematol 86:786, 1994
10. Bosch F, Jares P, Campo E, Lopez-Guillermo A, Piris MA, Villamor N, Tassies D, Jaffe ES, Montserrat E, Rozman C, Cardesa A: PRAD-1/cyclin D1 gene overexpression in chronic lymphoproliterative disorders: A highly specific marker of mantle cell lymphoma. Blood 84:2726, 1994
11. Jiang W, Zhang Y-J, Kahn SM, Hollstein MC, Santella RM, Lu S-H, Harris CC, Montesano R, Weinstein IB: Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer. Proc Natl Acad Sci USA 90:9026, 1993
12. Quelle DE, Ashmun RA, Shurtleff SA, Kato J, Bar-Sagi D, Roussel M, Sherr CJ: Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev 7:1559, 1993
13. Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G: Cyclin D1 is a nuclear protein required for cell cycle progression in G1 Genes Dev 7:812, 1993
14. Bartkova J, Lukas J, Muller H, Lutzhoft D, Strauss M, Bartek J: Cyclin D1 protein expression and function in human breast cancer Int J Cancer 57:353, 1994
15. Tam SW, Theodoras AM, Shay JW, Draetta GF, Pagano M: Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: Association with cdk4 is required for cyclin D1 function in G1 progression. Oncogene 9:2663, 1994
16. Hinds PH, Dowdy S, Eaton EN, Arnold A, Weinberg RA: Function of a human cyclin gene as an oncogene. Proc Natl Acad Sci USA 91:709, 1994
17. Lovec H, Grzeschiczek A, Kowalski M-B, Moroy T: Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphomas in transgenic mice. EMBO J 13:3487, 1994
18. Lardelli P, Bookman MA, Sundeen J, Longo DL, Jaffe ES. Lymphocytic lymphoma of intermediate differentiation. Morphologic and Immunophenotypic spectrum and clinical correlations. Am J Surg Pathol 14:752, 1990
19. Lennert K, Feller AC: Histopathology of Non-Hodgkin's Lymphomas. New York, NY, Springer-Verlag, 1992
20. Ott MM, Ott G, Porowski P, Gunzer U, Feller AC, Muller-Hermelink HK: The anaplastic variant of centrocytic lymphoma is marked by frequent rearrangements of the bcl-1 gene and high proliferation indices. Histopathology 24:329, 1994
21. Lane DP: p53, guardian of the genome. Nature 358:15, 1992
22. Kastan MB, Zhan Q, El-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, Fornace AJ Jr: A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71:587, 1992
23. Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 253:49, 1991
24. Gaidano G, Ballerini P, Gong JZ, Inghirami G, Neri A, Newcomb EW, Magrath IT, Knowles DM, Dalla-Favera R: p53 mutations in human lymphoid malignancies: Association with Burkitt lymphoma and chronic lymphocytic leukemia. Proc Natl Acad Sci USA 88:5413, 1991
25. Ichikawa A, Hotta T, Takagi N, Tsushita K, Kinoshita T, Nagai H, Murakami Y, Hayashi K, Saito H: Mutations of p53 gene and their relation to disease progression in B-cell lymphoma. Blood 79:2701, 1992
26. Imamura J, Miyoshi I, Koeffler HP: p53 in hematologic malignancies. Blood 84:2412, 1994
27. Prokocimer M, Rotter V: Structure and function of p53 in normal cells and their aberrations in cancer cells: Projection on the hematologic cell lineages. Blood 84:2391, 1994
28. Villuendas R, Piris MA, Algara P, Sanchez-Beato M, Sanchez-Verde L, Martinez JC, Orradre JL, Garcia P, Lopez C, Martinez P: The expression of p53 protein in non-Hodgkin's lymphomas is not always dependent on p53 mutations. Blood 82:3151, 1993
29. Sander CA, Yano T, Clark HM, Harris C, Longo DL, Jaffe ES, Raffeld M: p53 mutation is associated with progression in follicular lymphomas. Blood 82:1994, 1993
30. LoCoco F, Gaidano G, Louie DC, Offit K, Chaganti RSK, Dalla-Favera R: p53 mutations are associated with histologic transformation of follicular lymphoma. Blood 82:2289, 1993
31. Banks PM, Chan J, Clearly ML, Delsol G, de Wolf-Peeters C, Gatter K, Grogan TM, Harris NL, Isaacson PG, Jaffe ES, Mason D, Piteri S, Ralfkiaer E, Stein H, Warnke RA: Mantle cell lymphoma. A proposal for unification of morphologic, immunologic, and molecular data. Am J Surg Pathol 16:637, 1992
32. Zucca E, Stein H, Coiffier B: European lymphoma task force (ELTF): Report of the workshop on mantle cell lymphoma (MCL). Ann Oncol 5:507, 1994
33. Glisin V, Crkvenjakov R, Byus C: Ribonucleic acid isolated by cesium chloride centrifugation. Biochemistry 13:2633, 1974
34. Onta M, Iwahance H, Kanazawa H, Hayashi K, Sekiya T: Detection of polymorphisms of human DNA by gel electrophoresis as single-stranded conformation polymorphisms. Proc Natl Acad Sci 86:2766, 1989
35. Peinado MA, Fernandez-Renart M, Capella G, Wilson L, Perucho M: Mutations in the p53 suppressor gene do not correlate with c-K-ras oncogene mutations in colorectal cancer. Int J Oncol 2:123, 1993
36. Sambrock J, Fritsch EF, Maniatis T (eds): Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
37. Beck JS, Kwitek AE, Cogen PH: A denaturing gradient gel electrophoresis assay for sensitive detection of p53 mutations. Hum Genet 91:25, 1993
38. Sheffield VC, Cox DR, Lerman LS, Myers RM: Attachement of a 40-base-pair G+C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. Proc Natl Acad Sci USA 86:232, 1989
39. Prosser J, Condie A: Biallelic ApaI polymorphism of the human p53 gene (TP53). Nucleic Acid Res 19:4799, 1991
40. Ory K, Legros Y, Auguin C, Soussi T: Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation. EMBO J 13:3496, 1994
41. Wattel E, Preudhomme C, Hecquet B, Vanrumbeke M, Quesnel B, Dervite I, Morel P, Fenaux P: p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 84:3148, 1994
42. + anaplastic large-cell lymphoma: High frequency of c-myc proto-oncogene activation. Blood 83:3581, 1994
43. Matsushima AY, Cesarman E, Chadburn A, Knowles DM: Post-thymic T cell lymphomas frequently overexpress p53 protein but infrequently exhibit p53 gene mutations. Am J Pathol 144:573, 1994
44. Matsushima AY, Cesarman E, Knowles DM: Mutations are not detected outside p53 gene exons 5 to 9 in lymphoid tumors. Lab Invest 70.115, 1994 (abstr)
45. Danova M, Giordano M, Mazzani G, Ricardi A: Expression of p53 protein during the cell cycle measured by flow cytometry in human leukemia. Leuk Res 14:417, 1990
46. Chang H, Benchimol S, Minden MD, Messner HA: Alterations of p53 and c-myc in the clonal evolution of malignant lymphoma. Blood 83:452, 1994
47. Swerdlow SH, Habeshaw JA, Murray LJ, Dhaliwal HS, Lister TA, Stansfeld AG: Centrocytic lymphoma: A distinct clinicopathologic and immunologic entity. A multiparameter study of 18 cases at diagnosis and relapse. Am J Pathol 113:181, 1983