Blastic transformation of mantle cell lymphoma: Genetic evidence for a clonal link between the two stages of the tumour

Histopathology

Volumn 35, Issue 4, 1999, Pages 355-359

  Laszlo T ^a   Matolcsy, A ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Blastic transformation; Clonality; Mantle cell lymphoma

Indexed keywords

ARTICLE; CASE REPORT; CELL TRANSFORMATION; GENE REARRANGEMENT; GENETIC LINKAGE; HUMAN; IMMUNOPHENOTYPING; LYMPHOCYTE CLONE; MANTLE CELL LYMPHOMA; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLAST CRISIS; DNA, NEOPLASM; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOPHENOTYPING; LYMPHOMA, MANTLE-CELL; MOLECULAR SEQUENCE DATA;

EID: 0032759433     PISSN: 03090167     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2559.1999.00745.x     Document Type: Article

References (15)

1. Lardelli P, Bookman MA, Sundeen J, Longo DL, Jaffe ES. Lymphocytic lymphoma of intermediate differentiation: morphologic and immunophenotypic spectrum and clinical correlations. Am. J. Surg. Pathol. 1990; 14; 752-763.
2. Harris NL, Jaffie ES, Stein H et al. A revised European-American classification of lymphoid neoplasms: a proposal from the international Lymphoma Study Group. Blood 1994; 84; 1361-1392.
3. Norton AJ, Matthews J, Pappa V et al. Mantle cell lymphoma: natural history defined in a serially biopsied population over a 20-year period. Ann. Oncol. 1995; 6; 249-256.
4. Anderson MM, Singleton TP, Ross CW, Sheldun S, Schnitzer B. Leukemic phase of mantle cell lymphoma, blastic variant. Mod. Pathol. 1995; 8; 105A (Abstract).
5. Kaleem Z, Wakoff AR, Smith RS, Hess JL. Blastic transformation of mantle cell lymphoma. Arch. Pathol. Lab. Med. 1996; 120; 577- 580.
6. Korsmayer SJ, Hieter PA, Ravetch JV, Poplack DG, Waldmann TA, Leder P. Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells. Proc. Natl. Acad. Sci. USA 1981; 78; 7096-7100.
7. Matolcsy A, Inghirami G, Knowles DM. Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and subsequential large cell lymphoma). Blood 1994; 83; 1363-1372.
8. Matolcsy A. High-grade transformation of low-grade non- Hodgkin's lymphomas: mechanisms of tumor progression. Leukemia Lymphoma 1999 (in press).
9. Volkenandt M, Dicker AP, Fanin R, Banerjee D, Albino A, Bertino JR. Polymerase chain reaction analysis of DNA from paraffin-embedded tissue. In White BA ed. PCR Protocols. Totowa, New Jersey: Humana Press, 1993: 81-88.
10. Kabat EA, Wu TT, Perry HM, Gottesmann KS, Foeller C. Sequences of Proteins of Immunological Interest. U.S. Department of Health and Human Services, Public Health Service, National institutes of Health, 1991.
11. Traweek ST, Liu J. Johnson RM, Winberg CD, Rappaport H. High-grade transformation of chronic lymphocytic leukemia and low-grade non-Hodgkin's lymphoma. Genotypic confirmation of clonal identity. Am. J. Clin. Pathol. 1993; 100; 519-526.
12. Cuneo A, De Angeli C, Robert MG et al. Richter's syndrome in a case of atypical chronic lymphocytic leukaemia with the 1(11;14)(q13;32): role for a p53 exon 7 gene mutation. Br. J. Haematol. 1996; 92; 375-391.
13. Du MQ, Diss TC, Xu CF, Wotherspoon AC, Isaacsan PG, Pan LX. Ongoing immunoglobulin gene mutations in mantle cell lymphomas. Br. J. Haematol. 1997; 96; 124-131.
14. Andersen NS, Donovan JW, Borus JS et al. Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease. Blood 1997; 90; 4212-4221.
15. Pittaluga S, Tierens A, Pinyol M, Campo E, Delabie J. De Wolf-Peeters C. Blastic variant of mantle cell lymphoma shows a heterogenous pattern of somatic mutations of the rearranged immunoglobulin heavy chain variable genes. Br. J. Haematol. 1998; 102; 1301-1306.