Increased number of chromosomal imbalances and high-level DNA amplifications in mantle cell lymphoma are associated with blastoid variants

Blood

Volumn 93, Issue 12, 1999, Pages 4365-4374

  Beà, Sílvia ^b   Ribas, Maria ^b   Hernández, Jesús M ^b   Bosch, Francesc ^b   Pinyol, Magda ^b   Hernández, Luis ^b   Luis García, Juan ^b   Flores, Teresa ^b   González, Marcos ^b   López Guillermo, Armando ^b   Piris, Miguel A ^b   Cardesa, Antonio ^b   Montserrat, Emilio ^b   Miró, Rosa ^b   Campo, Elías ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; PROTEIN P53;

ARTICLE; BLASTOCYST; CHROMOSOME 13; CHROMOSOME ABERRATION; CHROMOSOME LOSS; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; DNA HYBRIDIZATION; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENE INACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; MALE; MANTLE CELL LYMPHOMA; PRIORITY JOURNAL;

BLOTTING, SOUTHERN; CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 7; FEMALE; GENE AMPLIFICATION; HUMANS; LYMPHOCYTES; LYMPHOMA, SMALL CLEAVED-CELL, DIFFUSE; MALE; NUCLEIC ACID HYBRIDIZATION; TRANSLOCATION, GENETIC;

EID: 0033564352     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Banks PM, Chan J, Cleary ML, Delsol G, De Wolf-Peeters C, Gatter K, Grogan TM, Harris NL, Isaacson PG, Jaffe ES, Mason D, Pileri S, Ralfkiaer E, Stein H, Warnke R: Mantle cell lymphoma: A proposal for unification of morphologic, immunologic, and molecular data. Am J Surg Pathol 16:637, 1992
2. Ott G, Kalla J, Ott MM, Schryen B, Katzenberger T, Muller JG, Muller-Hermelink HK: Blastoid variants of mantle cell lymphoma: Frequent bcl-1 rearrangements at the major translocation cluster region and tetraploid chromosome clones. Blood 89:1421, 1997
3. Lardelli P, Bookman MA, Sundeen J, Longo DL, Jaffe ES: Lymphocytic lymphoma of intermediate differentiation: Morphologic and immunophenotypic spectrum and clinical correlations. Am J Surg Pathol 14:752, 1990
4. Bosch F, Lopez Guillermo A, Campo E, Ribera JM, Conde E, Piris MA, Vallespi T, Woessner S, Montserrat E: Mantle cell lymphoma: Presenting features, response to therapy, and prognostic factors. Cancer 82:567, 1998
5. Raffeld M, Jaffe ES: bcl-1, t(11;14), and mantle cell-derived lymphomas. Blood 78:259, 1991
6. Rosenberg CL, Wong E, Petty EM, Bale AE, Tsujimoto Y, Harris NL, Arnold A: PRAD1, a candidate BCL1 oncogene: Mapping and expression in centrocytic lymphoma. Proc Natl Acad Sci USA 88:9638, 1991
7. Bosch F, Jares P, Campo E, Lopez-Guillermo A, Piris MA, Villamor N, Tassies D, Jaffe ES, Montserrat E, Rozman C, Cardesa A: Prad-1/cyclin D1 gene overexpression in chronic lymphoproliferative disorders: A highly specific marker of mantle cell lymphoma. Blood 84:2726, 1994
8. Vaandrager JW, Schuuring E, Zwikstra E, de Boer CJ, Kleiverda KK, van Krieken JH, Kluin-Nelemans HC, van Ommen GJ, Raap AK, Kluin PM: Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization. Blood 88:1177, 1996
9. Hinds PW, Dowdy SF, Eaton EN, Arnold A, Weinberg RA: Function of a human cyclin gene as an oncogene. Proc Natl Acad Sci USA 91:709, 1994
10. Lovec H, Grzeschiczek A, Kowalski MB, Moroy T: Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 13:3487, 1994
11. Hernandez L, Fest T, Cazorla M, Teruya-Feldstein J, Bosch F, Peinado MA, Piris MA, Montserrat E, Cardesa A, Jaffe ES, Campo E, Raffold M: P53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas. Blood 87:3351, 1996
12. Greiner TC, Moynihan MJ, Chan WC, Lytle DM, Pedersen A, Anderson JR, Weisenburger DD: P53 mutations in mantle cell lymphoma are associated with variant cytology and predict a poor prognosis. Blood 87:4302, 1996
13. waf1 genes are associated with aggressive variants of mantle cell lymphomas. Blood 89:272, 1997
14. Dreyling MH, Bullinger L, Ott G, Stilgenbauer S, Muller-Hermelink HK, Bentz M, Hiddemann W, Dohner H: Alterations of the cyclin D1/p16-pRb pathway in mantle cell lymphoma. Cancer Res 57:4608, 1997
15. Weisenburger DD, Sanger WG, Armitage JO, Purtilo DT: Intermediate lymphocytic lymphoma: Immunophenotypic and cytogenetic findings. Blood 69:1617, 1987
16. Johansson B, Mertens F, Mitelman F: Cytogenetic evolution patterns in non-Hodgkin's lymphoma. Blood 86:3905, 1995
17. Argatoff LH, Connors JM, Klasa RJ, Horsman DE, Gascoyne RD: Mantle cell lymphoma: A clinicopathologic study of 80 cases. Blood 89:2067, 1997
18. Nowotny H, Karlic H, Gruner H, Hirsch J, Vesely M, Nader A, Heinz R: Cytogenetic findings in 175 patients indicate that items of the kiel classification should not be disregarded in the real classification of lymphoid neoplasms. Ann Hematol 72:291, 1996
19. Brito-Babapulle V, Ellis J, Matutes E, Oscier D, Khokhar T, MacLennan K, Catovsky D: Translocation t(11;14)(q13;q32) in chronic lymphoid disorders. Genes Chromosomes Cancer 5:158, 1992
20. Houldsworth J, Chaganti RS: Comparative genomic hybridization: An overview. Am J Pathol 145:1253, 1994
21. Pinyol M, Campo E, Nadal A, Terol MJ, Jares P, Nayach I, Fernandez PL, Piris MA, Montserrat E, Cardesa A: Detection of the bcl-1 rearrangement at the major translocation cluster in frozen and paraffin-embedded tissues of mantle cell lymphomas by polymerase chain reaction. Am J Clin Pathol 105:532, 1996
22. Matlashewski GJ, Tuck S, Pim D, Lamb P, Schneider J, Crawford LV: Primary structure polymorphism at amino acid residue 72 of human p53. Mol Cell Biol 7:961, 1987
23. Baron BW, Nucifora G, McCabe N, Espinosa, III, Le Beau MM, McKeithan TW: Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas. Proc Natl Acad Sci USA 90:5262, 1993
24. Boix J, Fibla J, Yuste V, Piulats JM, Llecha N, Comella JX: Serum deprivation and protein synthesis inhibition induce two different apoptotic processes in N18 neuroblastoma cells. Exp Cell Res 238:422, 1998
25. Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP: A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 323:643, 1986
26. ink4a-insensitive cdk4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science 269:1281, 1995
27. Alkema MJ, Jacobs H, van Lohuizen M, Berns A: Perturbation of B and T cell development and predisposition to lymphomagenesis in Emu bmi1 transgenic mice require the bmi1 ring finger. Oncogene 15:899, 1997
28. Kaplan GL, Meier P: Non-parametric stimulation from incomplete observations. J Am Stat Assoc 53:547, 1958
29. Peto R, Pike MC: Conservatism of the approximation sigma (O-E)2-E in the logrank test for survival data or tumor incidence data. Biometrics 29:579, 1973
30. Baron BW, Billstrand C, Madronero L, McKeithan TW: HindIII polymorphism in the bc16 gene. Hum Mol Genet 2:1513, 1993
31. Jares P, Campo E, Pinyol M, Bosch F, Miquel R, Fernandez PL, Sanchez-Beato M, Soler F, Perez-Losada A, Nayach I, Mallofre C, Piris MA, Montserrat E, Cardesa A: Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas. Correlation with cyclin D1 (PRAD1/CCND1) mRNA levels and proliferative activity. Am J Pathol 148:1591, 1996
32. Monni O, Oinonen R, Elonen E, Franssila K, Teerenhovi L, Joensuu H, Knuutila S: Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma. Genes Chromosomes Cancer 21:298, 1998
33. Dierlamm J, Rosenberg C, Stul M, Pittaluga S, Wlodarska I, Michaux L, Dehaen M, Verhoef G, Thomas J, de Kelver W, Bakker-Schut T, Cassiman JJ, Raap AK, De Wolf-Peeters C, Van den Berghe H, Hagemeijer A: Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization. Leukemia 11:747, 1997
34. Barth TFE, Döhner H, Werner CA, Stilgenbauer S, Schlotter M, Pawlita M, Lichter R, Möller P, Bentz M: Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract. Blood 91:4321, 1998
35. Bentz M, Dohner H, Huck K, Schutz B, Ganser A, Joos S, du Manoir S, Lichter P: Comparative genomic hybridization in the investigation of myeloid leukemias. Genes Chromosomes Cancer 12:193, 1995
36. Chan WY, Wong N, Chan AB, Chow JH, Lee JC: Consistent copy number gain in chromosome 12 in primary diffuse large cell lymphomas of the stomach. Am J Pathol 152:11, 1998
37. Joos S, Otano-Joos MI, Ziegler S, Bruderlein S, du Manoir S, Bentz M, Moller P, Lichter P: Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the rel gene. Blood 87:1571, 1996
38. Karhu R, Knuutila S, Kallioniemi OP, Siltonen S, Aine R, Vilpo L, Vilpo J: Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: A study by comparative genomic hybridization. Genes Chromosomes Cancer 19:286, 1997
39. Avet-Loiseau H, Vigier M, Moreau A, Mellerin MP, Gaillard F, Harousseau JL, Bataille R, Milpied N: Comparative genomic hybridization detects genomic abnormalities in 80% of follicular lymphomas. Br J Haematol 97:119, 1997
40. Bentz M, Werner CA, Dohner H, Joos S, Barth TF, Siebert R, Schroder M, Stilgenbauer S, Fischer K, Moller P, Lichter P: High incidence of chromosomal imbalances and gene amplifications in the classical follicular variant of follicle center lymphoma. Blood 88:1437, 1996
41. Houldsworth J, Mathew S, Rao PH, Dyomina K, Louie DC, Parsa N, Offit K, Chaganti RS: Rel proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. Blood 87:25, 1996
42. Monni O, Joensuu H, Franssila K, Klefstrom J, Alitalo K, Knuutila S: Bcl2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma. Blood 90:1168, 1997
43. Monni O, Joensuu H, Franssila K, Knuutila S: DNA copy number changes in diffuse large B-cell lymphoma. Blood 87:5269, 1996
44. Cigudosa JC, Rao PH, Calasanz MJ, Odero MD, Michaeli J, Jhanwar SC, Chaganti RSK: Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization. Blood 91:3007, 1998
45. Juliusson G, Oscier DG, Fitchett M, Ross FM, Stockdill G, Mackie MJ, Parker AC, Castoldi GL, Cuneo A, Knuutila S, Elonen E, Gahrton G: Prognostic subgroups in B-cell chronic lymphocytic defined by specific chromosomal abnormalities. N Engl J Med 323:720, 1990
46. Brown AG, Ross FM, Dunne EM, Steel CM, Weir-Thompson EM: Evidence for a new tumour suppressor locus (dbm) in human B-cell neoplasia telomeric to the retinoblastoma gene. Nat Genet 3:67, 1993
47. Stilgenbauer S, Nickolenko J, Wilhelm J, Wolf S, Weitz S, Döhner K, Boehn T, Döhner H, Lichter P: Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma. Oncogene 16:1891, 1998
48. Ben-Yehuda D, Houldsworth J, Parsa NZ, Chaganti RS: Gene amplification in non-Hodgkin's lymphoma. Br J Haematol 86:792, 1994
49. Werner CA, Dohner H, Joos S, Trumper LH, Baudis M, Barth TF, Ott G, Moller P, Lichter P, Bentz M: High-level DNA amplifications are common genetic aberrations in B-cell neoplasms. Am J Pathol 151:335, 1997
50. Knuutila S, Bjorkqvist AM, Autio K, Tarkkanen M, Wolf M, Monni O, Szymanska J, Larramendy ML, Tapper J, Pere H, el-Rifai W, Hemmer S, Wasenius VM, Vidgren V, Zhu Y: DNA copy number amplifications in human neoplasms: Review of comparative genomic hybridization studies. Am J Pathol 152:1107, 1998
51. Coquelle A, Pipiras E, Toledo F, Buttin G, Debatisse M: Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons. Cell 89:215, 1997
52. Koduru PR, Raju K, Vadmal V, Menezes G, Shah S, Susin M, Kolitz J, Broome JD: Correlation between mutation in p53, p53 expression, cytogenetics, histologic type, and survival in patients with B-cell non-Hodgkin's lymphoma. Blood 90:4078, 1997
53. Campo E, de la Calle Martin O, Miquel R, Palacin A, Romero M, Fabregat V, Vives J, Cardesa A, Yague J: Loss of heterozygosity of p53 gene and p53 protein expression in human colorectal carcinomas. Cancer Res 51:4436, 1991
54. Khatib ZA, Matsushime H, Valentine M, Shapiro DN, Sherr CJ, Look AT: Coamplification of the cdk4 gene with mdm2 and gli in human sarcomas. Cancer Res 53:5535, 1993
55. Reifenberger G, Ichimura K, Reifenberger J, Elkahloun AG, Meltzer PS, Collins VP: Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests cdk4/sas and mdm2 as independent amplification targets. Cancer Res 56:5141, 1996
56. Rao PH, Houldsworth J, Dyomina K, Parsa NZ, Cigudosa JC, Louie DC, Popplewell L, Offit K, Jhanwar SC, Chaganti RS: Chromosomal and gene amplification in diffuse large B-cell lymphoma. Blood 92:234, 1998
57. Alkema MJ, Wiegant J, Raap AK, Berns A, van Lohuizen M: Characterization and chromosomal localization of the human proto-oncogene bmi-1. Hum Mol Genet 2:1597, 1993
58. Imamura J, Miyoshi I, Koeffler HP: P53 in hematologic malignancies. Blood 84:2412, 1994
59. INK4a gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas. Blood 91:2977, 1998
60. Offit K, Jhanwar SC, Ladanyi M, Filippa DA, Chaganti RS: Cytogenetic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: Correlations between recurrent aberrations, histology, and exposure to cytotoxic treatment. Genes Chromosomes Cancer 3:189, 1991
61. Richardson ME, Chen QG, Filippa DA, Offit K, Hampton A, Koduru PR, Jhanwar SC, Lieberman PH, Clarkson BD, Chaganti RS: Intermediate-to high-grade histology of lymphomas carrying t(14;18) is associated with additional nonrandom chromosome changes. Blood 70:444, 1987
62. Yunis JJ, Frizzera G, Oken MM, McKenna J, Theologides A, Arnesen M: Multiple recurrent genomic defects in follicular lymphoma. A possible model for cancer. N Engl J Med 316:79, 1987
63. Garcia-Sanz R, Gonzalez M, Vargas M, Chillon MC, Balanzategui A, Barbon M, Flores MT, San Miguel JF: Deletions and rearrangements of cyclin-dependent kinase 4 inhibitor gene p16 are associated with poor prognosis in B-cell non-Hodgkin's lymphomas. Leukemia 11:1915, 1997