A role for smooth endoplasmic reticulum membrane cholesterol ester in determining the intracellular location and regulation of sterol-regulatory-element-binding protein-2

Biochemical Journal

Volumn 358, Issue 2, 2001, Pages 415-422

  Iddon, C R ^a   Wilkinson, J ^a   Bennett, A J ^a   Bennett, J ^a   Salter, A M ^a   Higgins, J A ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Acyl CoA:cholesterol acyltransferase; Cholesterol feeding; HMG CoA reductase; LDL receptor; Simvastatin

Indexed keywords

CENTRIFUGATION; GENES; LIPIDS; METABOLISM; PROTEINS;

HOMEOSTASIS; STEROL-REGULATORY-ELEMENT-BINDING PROTEINS (SREBP);

CHOLESTEROL;

ACYLTRANSFERASE INHIBITOR; AVASIMIBE; CHOLESTEROL ESTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; IODIXANOL; LOW DENSITY LIPOPROTEIN RECEPTOR; MEMBRANE LIPID; MESSENGER RNA; SIMVASTATIN; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CENTRIFUGATION; CHOLESTEROL INTAKE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; GOLGI COMPLEX; LIPID COMPOSITION; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; SMOOTH ENDOPLASMIC RETICULUM; SYRIAN HAMSTER;

ACETATES; ANIMALS; CHOLESTEROL; CHOLESTEROL ESTERS; CRICETINAE; DIET, ATHEROGENIC; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM, SMOOTH; ENZYME INHIBITORS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; INTRACELLULAR MEMBRANES; LIVER; MESOCRICETUS; RECEPTORS, LDL; RNA, MESSENGER; SIMVASTATIN; STEROL O-ACYLTRANSFERASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; SULFONIC ACIDS; TRANSCRIPTION FACTORS; TRIGLYCERIDES;

EID: 0035448312     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3580415     Document Type: Article

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