Stromal cell-derived factor 1α-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways

Journal of Immunology

Volumn 166, Issue 5, 2001, Pages 3067-3074

  Cherla, R P ^a   Ganju, R K ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CHEMOATTRACTANT; CHEMOKINE RECEPTOR CXCR4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CHEMOTAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOCYTE MIGRATION; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SECOND MESSENGER; SIGNAL TRANSDUCTION; STEM CELL; T LYMPHOCYTE;

EID: 0035284742     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.5.3067     Document Type: Article

References (83)

1. Chemokines
2. Chemokine receptors: Gateways to inflammation and infection
3. Chemoattractant signaling and leukocyte activation
4. The pro-inflammatory seven-transmembrane segment receptors of the leukocyte
5. Chemokines, inflammation and the immune system
6. Chemokines-chemotactic cytokines that mediate inflammation
7. Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes
8. Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method
9. The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
10. HIV-I entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
11. + progenitors to peripheral blood
12. Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: Rapid internalization and recycling upon activation
13. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
14. CD4-independent association between HIV-1 gp120 and CXCR4: Functional chemokine receptors are expressed in human neurons
15. Chemokine receptors: Keys to AIDS pathogenesis?
16. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
17. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
18. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
19. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development
20. Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation
21. The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4
22. The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation
23. The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways
24. Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5
25. Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling
26. Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration
27. The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes
28. Nitric oxide in excitable tissues: Physiological roles and disease
29. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
30. Molecular biology of nitric oxide synthases
31. Neuronal protection and destruction by NO
32. Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death
33. Nitric oxide inhibits Fas-induced apoptosis
34. Autocrine nitric oxide modulates CD95-induced apoptosis in γδ T lymphocytes
35. Expression of nitric oxide synthase in human peripheral blood mononuclear cells and neutrophils
36. Expression of human inducible nitric oxide synthase gene in T-cell lines infected with human T-cell leukemia virus type-I and primary adult T-cell leukemia cells
37. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
38. The Akt kinnase signals directly to endothelial nitric oxide synthase
39. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
40. p130cas is a cellular target protein for tyrosine nitration induced by peroxynitrite
41. The NF-κB and IκB proteins: New discoveries and insights
42. In murine 3T3 fibroblasts, different second messenger pathways resulting in the induction of NO synthase II (iNOS) converge in the activation of transcription factor NF-κB
43. Nitric oxide-induced reduction of lung cell and whole lung thioredoxin expression is regulated by NF-κB
44. Co-stimulatory effect of nitric oxide on endothelial NF-κB implies a physiological self-amplifying mechanism
45. Exogenous nitric oxide elicits chemotaxis of neutrophils in vitro
46. Role of endothelial nitric oxide synthase in endothelial cell migration
47. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells
48. Permissive role of nitric oxide in endothelin-induced migration of endothelial cells
49. β-Chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK
50. RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes
51. Serine and cysteine proteinase inhibitors prevent nitric oxide production by activated macrophages by interfering with transcription of the inducible NO synthase gene
52. Role of nuclear factor κB in cytokine-induced nitric oxide and tetrahydrobiopterin synthesis in rat neonatal cardiac myocytes
53. Evidence for involvement of the proteasome complex (26S) and NFκB in IL-1β-induced nitric oxide and prostaglandin production by rat islets and RINm5F cells
54. Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
55. Chemotaxis of primitive hematopoietic cells in response to stromal cell- derived factor-1
56. Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma
57. + cell proliferation in synergy with cytokines: Possible role in progenitor survival
58. The chemokine SDF-1 alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
59. Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway
60. Feedback inhibition of nitric oxide synthase activity by nitric oxide
61. Podokinesis in endothelial cell migration: Role of nitric oxide
62. Effects of nitric oxide on chondrocyte migration, adhesion, and cytoskeletal assembly
63. Nitric oxide influences injury-induced microglial migration and accumulation in the leech CNS
64. Nitric oxide inhibits migration of cultured endothelial cells
65. Nitric oxide modulates T-lymphocyte migration in Peyer's patches and villous submucosa of rat small intestine
66. Nitric oxide modulation of focal adhesions in endothelial cells
67. Nitric oxide alters chondrocyte function by disrupting cytoskeletal signaling complexes
68. Role of nuclear factor-κB activation in cytokine- and sphingomyelinase-stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells
69. Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein I and nuclear factor κB-binding sites
70. Insulin stimulates haptotactic migration of human epidermal keratinocytes through activation of NF-κB transcription factor
71. Involvement of proteasomes in migration and matrix metalloproteinase-9 production of oral squamous cell carcinoma
72. Induction of carcinoma cell migration on vitronectin by NF-κB-dependent gene expression
73. NF-κB is a target of AKT in antiapoptotic PDGF signalling
74. NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase
75. Stromal cell derived factor -1á stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: Roles of phosphoinositide-3 kinase and protein kinase C
76. Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells
77. Radicicol suppresses expression of inducible nitric-oxide synthase by blocking p38 kinase and nuclear factor-κB/Rel in lipopolysaccharide-stimulated macrophages
78. Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages
79. Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium
80. Nitric oxide regulates shear stress-induced early growth response-1: Expression via the extracellular signal-regulated kinase pathway in endothelial cells
81. Activation of mitogen-activated protein kinase pathways by cyclic GMP and cyclic GMP-dependent protein kinase in contractile vascular smooth muscle cells
82. Inhibition of extracellular signal-regulated kinase suppresses endotoxin-induced nitric oxide synthesis in mouse macrophages and in human colon epithelial cells
83. N-acetyl-L-cysteine potentiates interleukin-1β induction of nitric oxide synthase: Role of p44/42 mitogen-activated protein kinases