Role of nuclear factor-κB activation in cytokine- and sphingomyelinase- stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells

Endocrinology

Volumn 139, Issue 11, 1998, Pages 4506-4512

  Katsuyama, Koichi ^a   Shichiri, Masayoshi ^a   Marumo, Fumiaki ^a   Hirata, Yukio ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE SYNTHASE; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL CELL; ARTICLE; ELECTROPHORETIC MOBILITY; ENZYME ACTIVATION; ENZYME INDUCTION; GENETIC REGULATION; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; INFLAMMATORY CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEPTIC SHOCK; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0031764343     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.11.6309     Document Type: Article

References (43)

1. Moncada S, Palmer R, Higgs E 1991 Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43:109-142
2. Collins T 1993 Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion. Lab Invest 68:499-508
3. Cornwell TL, Arnold E, Boerth NJ, Lincoln TM 1994 Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP. Am J Physiol 267:C1405-C1413
4. Fukuo K, Hata S, Suhaia T, Nakahashi T, Shinto Y, Tsujimoto Y, Morimoto S, Ogihara T 1996 Nitric oxide induces upregulation of Fas and apoptosis in vascular smooth muscle. Hypertension 27:823-826
5. Thanos D, Maniatis T 1995 NF-κB: a lesson in family values. Cell 80:529-532
6. Beg AA, Finco TS, Nantermet PV, Baldwin AJ 1993 Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκB-α: a mechanism for NF-κB activation. Mol Cell Biol 13:3301-3310
7. Palombella VJ, Rando OJ, Goldberg AL, Maniatis T 1994 The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78:773-785
8. Schutze S, Potthoff K, Machleidt T, Berkovic D, Wiegmann K, Kronke M 1992 TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71:765-776
9. Machleidt T, Wiegmann K, Henkel T, Schutze S, Baeuerle P, Kronke M 1994 Sphingomyelinase activates proteolytic IκB-α degradation in a cell-free system. J Biol Chem 269:13760-13765
10. Kolesnick R, Golde DW 1994 The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77:325-328
11. Hirata Y, Tomita M, Yoshimi H, Ikeda M 1984 Specific receptors for atrial natriuretic factor (ANF) in cultured vascular smooth muscle cells of rat aorta. Biochem Biophys Res Commun 125:562-568
12. Kanno K, Hirata Y, Emori T, Ohta K, Eguchi S, Imai T, Marumo F 1992 L-Arginine infusion induces hypotension and increases diuresis/natriuresis with concomitant increased urinary excretion of nitrite/nitrate and cyclic GM P in human. Clin Exp Pharmacol Physiol 19:619-625
13. Eberhardt W, Kunz D, Hummel R, Pfeilschifter J 1996 Molecular cloning of the rat inducible nitric oxide synthase gene promoter. Biochem Biophys Res Commun 223:752-756
14. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
15. Iwashina M, Hirata Y, Imai T, Sato K, Marumo F 1996 Molecular cloning of endothelial, inducible nitric oxide synthase gene from rat aortic endothelial coll. Eur J Biochem 237:668-673
16. Hanson KD, Shichiri M, Follansbee MR, Sedivy JM 1994 Effects of c-myc expression on cell cycle progression. Mol Cell Biol 14:5748-3755
17. Tsujino M, Hirata Y, Imai T, Kanno K, Eguchi S, Ito H, Marumo F 1994 Induction of nitric oxide synthase gene by interleukin-1β in cultured rat cardiocytes. Circulation 90:375-383
18. Traenckner EB, Wilk S, Baeuerle PA 1994 A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-αB. EMBO J 13:5433-5441
19. Chen Z, Hagler J, Palombella VJ, Melandri F, Scherer D, Ballard D, Maniatis T 1995 Signal-induced site-specific phosphorylation targets IκB-α to the ubiquitin-proteasome pathway. Genes Dev 9:1586-1597
20. Belka C, Wiegmann K, Adam D, Holland R, Neuloh M, Herrmann F, Kronke M, Brach MA 1995 Tumor necrosis factor (TNF)-α activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase. EMBO J 14:1156-1165
21. Li S, Sedivy JM 1993 Raf-1 protein kinase activates the NF-κB transcription factor by dissociating the cytoplasmic NF-κB-IκB complex. Proc Natl Acad Sci USA 90:9247-9251
22. Park SK, Lin HL, Murphy S 1997 Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-κB binding to DNA. Biochem J 322:609-613
23. Thompson JE, Phillips RJ, Erdjument BH, Tempst P, Ghosh S 1995 IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80:573-582
24. Hannun YA 1994 The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269:3125-3128
25. Wiegmann K, Schutze S, Machleidt T, Witte D, Kronke M 1994 Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78:1005-1015
26. Zumbansen M, Stoffel W 1997 Tumor necrosis factor a activates NF-κB in acid sphingomyelinase-deficient mouse embryonic fibroblasts. J Biol Chem 272:10904-10909
27. Kuno K, Sukegawa K, Ishikawa Y, Orii T, Matsushima K 1994 Acid sphingomyelinase is not essential for the IL-1 and tumor necrosis factor receptor signaling pathway leading to NF-κB activation. Int Immunol 6:1269-1272
28. Higuchi M, Singh S, Jaffrezou JP, Aggarwal BB 1996 Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-κB activation. J Immunol 157:297-304
29. Johns LD, Sarr T, Ranges GE 1994 Inhibition of ceramide pathway does not affect ability of TNF-α to activate nuclear factor-κB. J Immunol 152:5877-5882
30. Slowik MR, De LL, Min W, Pober JS 1996 Ceramide is not a signal for tumor necrosis factor-induced gene expression but does cause programmed cell death in human vascular endothelial cells. Circ Res 79:736-747
31. Dbaibo GS, Obeid LM, Hannun YA 1993 Tumor necrosis factor-α (TNF-α) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-α from activation of nuclear factor-κB. J Biol Chem 268:17762-17766
32. Masamune A, Igarashi Y, Hakomori S 1996 Regulatory role of ceramide in interleukin (IL)-1β-induced E-selectin expression in human umbilical vein endothelial cells. Ceramide enhances IL-1β action, but is not sufficient for E-selectin expression. J Biol Chem 271:9368-9375
33. DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M 1997 A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388:548-554
34. Mercuric F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A 1997 IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science 278:860-866
35. Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV 1997 IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 278:866-869
36. Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M 1997 The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell 91:243-252
37. Regnier CH, Song HY, Gao X, Goeddel DV, Cao ZD, Rothe M 1997 Identification and characterisation of an IκB kinase. Cell 90:373-383
38. Malinin NL, Boldin MP, Kovalenko AV, Wallach D 1997 MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385:540-544
39. Lee FS, Hagler J, Chen ZJ, Maniatis T 1997 Activation of the IκB-α kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88:213-222
40. Read MA, Whitley MZ, Gupta S, Pierce JW, Best J, Davis RJ, Collins T 1997 Tumor necrosis factor α-induced E-selectin expression is activated by the nuclear factor-κB and c-Jun N-terminal kinase/p.38 mitogen-activated protein kinase pathways. J Biol Chem 272:2753-2761
41. Naumann M, Scheidereit C 1994 Activation of NF-κB in vivo is regulated by multiple phosphorylations. EMBO J 13:4597-4607
42. Hayashi T, Sekine T, Okamoto T 1993 Identification of a new serine kinase that activates NF-κB by direct phosphorylation. J Biol Chem 268:26790-26795
43. Boland MP, O'Neil LAJ 1998 Ceramide activates NF-κβ by inducing the proccssing of p105. J Biol Chem 273:15494-15500