Nitric oxide modulation of focal adhesions in endothelial cells

American Journal of Physiology - Cell Physiology

Volumn 276, Issue 6 45-6, 1999, Pages

  Goligorsky, Michael S ^a   Abedi, Husna ^b   Noiri, Eisei ^a   Takhtajan, Alice ^a   Lense, Sheri ^a   Romanov, Victor ^a   Zachary, Ian ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cell migration; Cytoskeleton; Focal adhesion kinase; Time lapse videomicroscopy; Tyrosine phosphorylation

Indexed keywords

FOCAL ADHESION KINASE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; PAXILLIN;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL SPREADING; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

EID: 0033027865     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.276.6.c1271     Document Type: Article

References (15)

1. Burridge, K., C. E. Turner, and L. H. Romer. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J. Cell Biol. 119: 893-903, 1992.
2. Burton, K., and D. L. Taylor. Traction forces of cytokinesis measured with optically modified elastic substrata. Nature 385: 450-454, 1997.
3. Caselli, A., G. Camici, G. Manao, G. Moneti, L. Pazzaglia, G. Cappugi, and G. Ramponi. Nitric oxide causes inactivation of the low molecular weight phosphotyrosine protein phosphatase. J. Biol Chem. 269: 24878-24882, 1994.
4. Condeelis, J. Life at the leading edge: the formation of cell protrusions. Annu. Rev. Cell Biol. 9: 411-444, 1993.
5. Crowley, E., and A. Horwitz. Tyrsine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions. J. Cell Biol. 131: 525-537, 1995.
6. Dhaunsi, G. S., C. Matthews, K. Kaur, and A. Hassid. NO increases protein tyrosine phasphatase activity in smooth muscle cells: relation to antimitogenesis. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H1342-H1349, 1997.
7. Frenkel, T. Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10: 248-253, 1998.
8. Giaever, I., and C. R. Keese. Micromotion of mammalian cells measured electrically. Proc. Natl. Acad. Sci. USA 88: 7896-7900, 1991.
9. Gilmore, A. P., and L. H. Romer. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol. Biol. Cell 7: 1209-1224, 1996.
10. Huttenlocher, A., M. H. Ginsberg, and A. F. Horwitz. Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity. J. Cell Biol. 134: 1551-1562, 1996.
11. Illc, D., Y. Furuta, S. Kanazawa, N. Takeda, K. Sobue, N. Nakatsuji, S. Nomura, J. Fujimoto, M. Okada, T. Yamamoto, and S. Aizawa. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature 377: 539-544, 1995.
12. Kornberg, L., H. S. Earp, J. T. Parsons, M. Schaller, and R. L. Juliano. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J. Biol. Chem. 267: 23439-23442, 1992.
13. Lauffenburger, D. A. Models for receptor-mediated cell phenomena: adhesion and migration. Annu. Rev. Biophys. Biophys. Chem. 20: 387-414, 1991.
14. Maher, P. A. Activation of phosphotyrosine phosphatase activity by reduction of cell-substrate adhesion. Proc. Natl. Acad. Sci. USA 90: 11177-11181, 1993
15. McCuskey, R. S., R. Urbaschek, and B. Urbaschek. The microcirculation during endotoxemia. Cardiovasc. Res. 32: 752-763, 1996.