JAGGED1 gene expression during human embryogenesis elucidates the wide phenotypic spectrum of Alagille syndrome

Hepatology

Volumn 32, Issue 3, 2000, Pages 574-581

  Crosnier, Cécile ^a   Attié Bitach, Tania ^b   Encha Razavi, Férechté ^b   Audollent, Sophie ^b   Soudy, Fardouss ^a   Hadchouel, Michelle ^a,c   Meunier Rotival, Michèle ^a   Vekemans, Michel ^b  

^a INSERM   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR;

ALAGILLE SYNDROME; ANGIOGENESIS; ARTICLE; CLINICAL FEATURE; EMBRYO; EMBRYO DEVELOPMENT; GENE; GENE EXPRESSION; HUMAN; NERVOUS SYSTEM DEVELOPMENT; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

EID: 0033839965     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.16600     Document Type: Article

References (42)

1. Mutations in the human Jagged1 gene are responsible for Alagille syndrome
2. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
3. Spectrum and frequency of Jagged1 (JAG1) mutations in Alagille syndrome patients and their families
4. Mutational analysis of the Jagged1 gene in Alagille syndrome families
5. Mutations in JAGGED1 gene are predominantly sporadic in Alagille syndrome
6. Genetic alterations in the JAG1 gene in Japenese patients with Alagille syndrome
7. Jagged-1 mutation analysis in Italian Alagille syndrome patients
8. Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): Review of 80 cases
9. Mouse Jagged1 physically interacts with Notch2 and other Notch receptors
10. The expression and function of Notch pathway genes in the developing rat eye
11. Expression pattern of Notch1, Serrate1, Serrate2 and Delta1 in tissues of the developing chick limb
12. Mouse Serrate-1 (Jagged-1): Expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4
13. Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: Parallels with Drosophila sense-organ development
14. Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear
15. Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear
16. Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development
17. The Notch signalling pathway in hair growth
18. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells
19. The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro
20. Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development
21. Rel/NF-κB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors
22. An antisense oligonucleotide to the Notch ligand Jagged enhances fibroblast growth factor-induced angiogenesis in vitro
23. Jagged: A mammalian ligand that activates Notchl
24. Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
25. Expression of the Sonic Hedgehog (SHH) gene during early human development and phenotypic expression of new mutations causing holoprosencephaly
26. Alagille syndrome: The widening spectrum of arteriohepatic dysplasia
27. Notch4/int3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene
28. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis
29. Variable morbidity in Alagille syndrome: A review of 43 cases
30. Renovascular hypertension and vascular anomalies in Alagille syndrome
31. Identification and cloning of the human homolog (JAG1) of the rat Jagged1 gene from the Alagille syndrome critical region at 20p12
32. The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome
33. Endothelial adhesion molecules in the development of the vascular tree: The garden of forking paths
34. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
35. Hepatic Jagged1 expression studies
36. Development of human peribiliary capillary plexus: A lectin-histochemal and immunohistochemical study
37. Small bowel atresia, biliary atresia and Alagille's syndrome
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39. Exocrine pancreatic insufficiency in syndromic paucity of interlobular bile ducts
40. Features of Alagille syndrome in 92 patients: Frequency and relation to prognosis
41. Temporal bone histopathologic findings in Alagille's syndrome