Neurotrophic and neurotoxic effects of nitric oxide on fetal midbrain cultures

Journal of Neurochemistry

Volumn 76, Issue 1, 2001, Pages 56-68

  Canals, S ^a   Casarejos, M J ^a   Rodriguez Martin E ^a   De Bernardo, S ^a   Mena, M A ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Apoptosis; Bcl 2 proteins; Dopamine neurones; Glia; Glutathione; Nitric oxide

Indexed keywords

DOPAMINE; GLUTATHIONE REDUCTASE; NEUROTROPHIC FACTOR; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL X; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CELL; CELL CULTURE; CELL DEATH; CHROMATIN CONDENSATION; DOPAMINERGIC NERVE CELL; DOSE TIME EFFECT RELATION; EMBRYO; GLIA CELL; MESENCEPHALON; NEURITE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; TISSUE CULTURE;

ANIMALS; APOPTOSIS; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYCLIC GMP; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HYDRAZINES; MESENCEPHALON; NEUROGLIA; NEURONS; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROGEN OXIDES; RATS; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 0035172744     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00010.x     Document Type: Article

References (81)

1. Inhibition of glutathione depletion by retinoic acid and tocopherol protects cultured neurons from staurosporine-induced oxidative stress and apoptosis
2. Inactivation of tyrosine hydroxylase by nitration following exposure to peroxinitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
3. Neurochemical studies of the mesolimbic dopaminergic pathway: Somatodendritic mechanisms and GABAergic neurons in rat ventral tegmentum
4. Extracellular signal-regulated kinase and p-38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha-gene expression in endotoxin-stimulated primary glial cultures
5. NADPH-diaphorase/nitric oxide synthase containing neurons in normal and Parkinson's disease putamen
6. Effect of peroxynitrite on the mitochondrial respiratory chain: Differential susceptibility of neurones and astrocytes in primary culture
7. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye-binding
8. The redox pathway of S-nitrosoglutathione, glutathione and nitric oxide in cell to neuron communications
9. A novel neuronal messenger molecule in brain: The free radical, nitric oxide
10. A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity
11. Toxicity of l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes
12. Evidence for a novel neurotrophic factor for dopaminergic neurons secreted from mesencephalic glial cell lines
13. Conditioned media derived from glial cell lines promote survival and differentiation of dopaminergic neurons in vitro: Role of mesencephalic glia
14. Comparative effects of several nitric oxide donors on intracellular cyclic GMP levels in bovine chromaffin cells: Correlation with nitric oxide production
15. Seizures increases basic fibroblast growth factor mRNA in adult rat forebrain neurons and glia
16. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
17. Protein nitration in Parkinson's disease
18. 15N-nitrate in biological fluids
19. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
20. Catecholaminergic expression in 2N27 immortal neural cell line is enhanced by glial-derived factors
21. Measurement of cyclic GMP formation
22. pH Dependent fluorescence of DNA and RNA in cytologic staining with '33342 Hoechst'
23. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo
24. Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: Involvement of the glutathione system
25. Localization of GTP cyclohydrolase in monoaminergic but not nitric oxide-producing cells
26. Understanding cell death in Parkinson's disease
27. Loss of glutathione (GSH) in Parkinson' disease: How does GSH act to protect dopaminergic neurons of the substantia nigra?
28. NONOates (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms
29. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
30. Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling
31. Peroxynitrite inactivation of tyrosine hydroxylase: Mediation by sulfhydryl oxidation, not tyrosine nitration
32. Intricate regulation of tyrosine hydroxylase activity and gene expression
33. Peroxynitrite- and nitrite-induced oxidation of dopamine: Implications for nitric oxide in dopaminergic cell loss
34. Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex
35. Astroglia in culture
36. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
37. Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor
38. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
39. Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: Evidence that astrocytes play an important role in antioxidative processes in the brain
40. N-acetylcysteine elicited increase in complex I activity in synaptic mitochondria from aged mice: Implications for treatment of Parkinson's disease
41. Activation of Akt kinase inhibits apoptosis and changes in bcl-2 and bax expression induced by nitric oxide in primary hippocampal neurons
42. Glutathione metabolism and its selective modification
43. The critical factor for L-DOPA toxicity on dopamine neurons is glia
44. Effects of dibutyryl cyclic AMP and retinoic acid on the differentiation on dopamine neurons: Prevention of cell death by dibutyryl cyclic AMP
45. Glia protects midbrain dopamine neurons in culture from L-DOPA toxicity through multiple mechanisms
46. The effect of glia-conditioned medium on dopamine neurons in culture. Modulation of apoptosis, tyrosine hydroxylase expression and 1-methyl-4-phenylpyridinium toxicity
47. Fibroblast growth factors: Structure-activity on dopamine neurons in vitro
48. Glial conditioned medium protects fetal rat midbrain neurons in culture from L-DOPA toxicity
49. A synergistic neurotrophic response to l-dihydroxyphenylalanine and nerve growth factor
50. Biochemical properties of monoamine-rich human neuroblastoma cells
51. Levodopa toxicity in foetal rat midbrain neurons in culture: Modulation by ascorbic acid
52. Neuronal death induced by SIN-1 in the presence of superoxide dismutase: Protection by cyclic GMP
53. Sparing of NADPH-diaphorase striatal neurons in Parkinson's and Alzheimer's diseases
54. Astroglial neurotrophic and neurite-promoting factors
55. Synthesis of nitric oxide in CNS glial cells
56. Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain
57. Nitric oxide induces c-fos gene expression via cyclic AMP response element binding protein (CREB) phosphorylation in rat retinal pigment epithelium
58. Neuronal-enriched cultures from embryonic rat ventral mesencephalon for pharmacological studies of dopamine neurons
59. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
60. Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease
61. Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture
62. A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on the culture medium
63. Neuroprotection by S-nitrosoglutathione of brain dopamine neurons from oxidative stress
64. Nitric oxide induces differentiation in the NB69 human catecholamine-rich cell line
65. Phosphorylation of tyrosine hydroxylase by cGMP-dependent protein kinase in intact bovine cromaffin cells
66. Intracellular redox state determines whether nitric oxide is toxic or protective to rat oligodendrocytes in culture
67. Maintenance of neuronal glutathione by glial cells
68. Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice
69. Detection of nitrosyl complexes in human substantia nigra, in relation to Parkinson's disease
70. Reduced and oxidized glutathione in human and monkey brain
71. Reduction of MPP+-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase
72. Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: An immunocytological study in the central nervous system
73. Mesencephalic type I astrocytes rescue dopaminergic neurons from death induced by serum deprivation
74. Astrocyte-dependent and independent phases of the development and survival of rat embryonic day 14 mesencephalic neurons in culture
75. Involvement of Bcl-2 family and caspase-3-like protease in NO-mediated neuronal apoptosis
76. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Application to mammalian blood and other tissue
77. Differences in the disposition and toxicity of 1-methyl-4-phenylpyridinium in cultured rat and mouse astrocytes
78. Final common pathways in neurodegenerative diseases: Regulatory role of the glutathione cycle
79. The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection
80. Nitric oxide protects against cellular damage and citotoxicity from reactive oxygen species
81. Kinetic characterization of the nitric oxide toxicity for PC12 cells: Effect of half-time of NO release