Final common pathways in neurodegenerative diseases: Regulatory role of the glutathione cycle

Neuroscience and Biobehavioral Reviews

Volumn 23, Issue 8, 1999, Pages 1079-1086

  Weber, G F ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Glutathione cycle; Homeostasis; Neurodegenerative diseases

Indexed keywords

4 AMINOBUTYRIC ACID; ARACHIDONIC ACID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC GMP DEPENDENT PROTEIN KINASE; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; DEGENERATIVE DISEASE; NEUROTOXICITY; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

EID: 0032716594     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(99)00041-X     Document Type: Article

References (50)

1. Farooqui A.A., Horrocks L.A. Invovlement of glutamate receptors, lipases, and phospholipases in long-term potentiation and neurodegeneration. J Neurosci Res. 38:1994;6-11.
2. Ciani E., Groneng L., Voltattorni M., Rolseth V., Contestabile A., Paulsen R.E. Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons. Brain Res. 728:1996;1-6.
3. Hawkins R.D., Zhou M., Arancio O. Nitric oxide and carbon monoxide as possible retrograde messengers in hippocampal long-term potentiation. J Neurobiol. 25:1994;652-665.
4. Beardsley T. Memories are made of ... Sci Am. 276:1997;32-33.
5. Li Y., Maher P., Schubert D. A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron. 19:1997;453-463.
6. Weiss V. Psychometric intelligence correlates with interindividual different rates of lipid peroxidation. Biomed Biochim Acta. 434:1984;755-763.
7. Coffey R.G., Hadden E.M., Hadden J.W. Phytohemagglutinin stimulation of guanylate cyclase in human lymphocytes. J Biol Chem. 256:1981;4418-4424.
8. Weber G.F., Abromson-Leeman S., Cantor H. A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death. Immunity. 2:1995;363-372.
9. Haliday E.M., Ramesha C.S., Ringold G.M. TNF induces c-fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metabolite. EMBO J. 10:1991;109-115.
10. Hoeck W.G., Ramesha C.S., Chang D.J., Fan N., Heller R.A. Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis. Proc Natl Acad Sci USA. 90:1993;4475-4479.
11. Reid T., Ramesha C.S., Ringold G.M. Resitance to killing by tumor necrosis factor in adipocyte cell line caused by a defect in arachidonic acid biosynthesis. J Biol Chem. 266:1991;16 580-16 586.
12. Itoh N., Yonehara S., Ishihi A., Yonehara M., Mizushima S., Sameshima M., Hase A., Seto Y., Nagata S. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell. 66:1991;233-243.
13. Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., Schmidt A.M. RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease. Nature. 382:1996;685-691.
14. Gudi T., Huvar I., Meinecke M., Lohmann S.M., Boss G.R., Pilz R.P. Regulation of gene expression by cGMP-dependent protein kinase. J Biol Chem. 271:1996;4597-4600.
15. Kayanoki Y., Fujii J., Islam K.N., Suzuki K., Kawata S., Matsuzawa Y., Taniguchi N. The protective role of glutathione peroxidase in apoptosis induced by reactive oxygen species. J Biochem. 119:1996;817-822.
16. 2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science. 271:1996;521-525.
17. Kim T.-W., Pettingel W.H., Jung Y.-K., Kovacs D.M., Tanzi R.E. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science. 277:1997;373-376.
18. Miyata M., Smith J.D. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides. Nature Gen. 14:1996;55-60.
19. Multhaup G., Schlicksupp A., Hesse L., Beher D., Ruppert T., Masters C.L., Beyreuther K. The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I). Science. 271:1996;1406-1409.
20. Bush A.I., Pettingell W.H., Multhaup G., Paradis Md, Vonsattel J.-P., Gusella J.F., Beyreuther K., Mastes C.L., Tanzi R.E. Rapid induction of Alzheimer Aβ amyloid formation by zinc. Science. 265:1994;1464-1467.
21. Markesbery W.R. Oxidative stress hypothesis in Alzheimer's disease. Free Rad Biol Med. 23:1997;134-147.
22. Wautier J.L., Wautier M.P., Schmidt A.M., Anderson G.M., Hori O., Zoukourian C., Capron L., Chappey O., Yan S.D., Brett J., et al. Advanced glycation end products (AGEs) on the surface of diabetic erythrocytes bind to the vessel wall via a specific receptor inducing oxidant stress in the vasculature: a link between surface-associated AGEs and diabetic complications. Proc Natl Acad Sci USA. 91:1994;7742-7746.
23. Miyata T., Hori O., Zhang J., Yan S.D., Ferran L., Iida Y., Schmidt A.M. The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidation-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis. J Clin Invest. 98:1996;1088-1094.
24. Goodman Y., Steiner M.R., Steiner S.M., Mattson M.P. Nordihydroguaiaretic acid protects hippocampal neurons against amyloid β-peptide toxicity and attenuates free radical and calcium accumulation. Brain Res. 654:1994;171-176.
25. Balcioglu A., Maher T.J. The measurement of nitric oxide release by kainic acid using a novel hemoglobin-trapping technique with microdialysis. Ann NY Acad Sci. 738:1994;282-288.
26. Volterra A., Trotti D., Floridi S., Racagni G. Reactive oxygen species inhibit high-affinity glutamate uptake: molecular mechanism and neuropathological implications. Ann NY Acad Sci. 738:1994;282-288.
27. Smith R.G., Appel S.H. Molecular approaches to amyotrophic lateral sclerosis. Ann Rev Med. 46:1995;133-145.
28. Plaitakis A., Nicklas W.J., Desnick R.J. Glutamate dehydrogenase deficiency in three patients with spinocerebellar syndrome. Ann Neurol. 7:1980;297-303.
29. - antiporter system. Neuroscience. 73:1996;201-208.
30. Murphy T.H., Miyamato M., Sastre A., Schaar R.L., Coyle J.T. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron. 2:1989;1547-1558.
31. Plaitakis A. Altered glutamatergic mechanisms and selective motor neuron degeneration in amyotrophic lateral sclerosis: possible role of glycine. Adv Neurol. 56:1991;319-326.
32. Bruijn L.I., Houseweart M.K., Kato S., Anderson K.L., Anderson S.D., Ohama E., Reaume A.G., Scott R.W., Cleveland D.W. Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science. 281:1998;1851-1854.
33. 2 plus Cu,Zn-superoxide dismutase reflects the activity of free copper released from oxidatively damaged enzyme. J Biol Chem. 267:1992;25 371-25 377.
34. Yim M.B., Chock P.B., Stadtman E.R. Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide. Proc Natl Acad Sci USA. 87:1990;5006-5010.
35. Wiedau-Pazos M., Goto J.J., Rabizadeh S., Gralla E.B., Roe J.A., Lee M.K., Valentine J.S., Bredesen D.E. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science. 271:1996;515-518.
36. Samanta S., Perkinton M.S., Morgan M., Williams R.J. Hydrogen peroxide enhances signal-responsive arachidonic acid release from neurons: role of mitogen-activated protein kinase. J Neurochem. 70:1998;2082-2090.
37. Barbour B., Szatkowski M., Ingledew N., Attwell D. Arachidonic acid induces prolonged inhibition of glutamate uptake into glial cells. Nature. 342:1998;918-920.
38. Volterra A., Trotti D., Cassutti P., Tromba C., Salvaggio A., Melcangi R.C., Racagni G. High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes. J Neurochem. 59:1992;600-606.
39. Barbeau A. Etiology of Parkinson's disease: a research strategy. Can J Neurol Sci. 11:1984;24-28.
40. Youdim M.B.H. Transition metals, ferritin, glutathione, and ascorbic acid in Parkinson's disease. J Neurochem. 52:1989;515-520.
41. Vial D., Piomelli D. Dopamine D2 receptors potentiate arachidonate release via activation of cytosolic, arachidonate-specific phospholipase A2. J Neurochem. 64:1995;2765-2772.
42. Martilla R.J., Roeyttae M., Lorentz H., Rinne U.K. Oxygen toxicity protecting enzymes in the human brain. J Neural Transm. 74:1988;87-95.
43. Ambani L.M., van Voert M.H., Murphy S. Brain peroxidase and catalase in Parkinson's disease. Arch Neurol. 32:1975;114-118.
44. Jenner P. Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease. Acta Neurol Scand. 87:(Suppl. 146):1993;6-13.
45. Perry T.L., Godin D.V., Hansen S. Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci Lett. 33:1982;305-310.
46. Perry T.L., Young W.W. Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci Lett. 67:1986;269-274.
47. Riederer P., Sofic E., Rausch W.-D., Schmidt B., Reynolds G.P., Jellinger K., Youdim B.H. Transition metals, glutathione, and ascorbic acid in Parkinsonian brains. J Neurochem. 52:1989;515-520.
48. Shukitt-Hale B., Denisova N.A., Strain J.G., Joseph J.A. Psychomotor effects of dopamine infusion under decreased glutathione conditions. Free Rad Biol Med. 23:1997;412-418.
49. Meister A. Selective modification of glutathione metabolism. Science. 220:1983;472-477.
50. Meister A. 5-Oxoprolinuria (pyroglutamic aciduria) and other disorders of glutathione biosynthesis. Stanbury J.B., Wyngaarden J.B., Fredrickson D.S. The metabolic basis of inherited disease. 1978;328-335 McGraw-Hill, New York.