Single administration of thrombopoietin to lethally irradiated mice prevents infectious and thrombotic events leading to mortality

Experimental Hematology

Volumn 29, Issue 1, 2001, Pages 30-40

  Mouthon, Marc Andr� ^a   Gaugler, Marie H�l�ne ^a   Van der Meeren, Anne ^a   Vandamme, Marie ^a   Gourmelon, Patrick ^a   Wagemaker, Gerard ^b  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Hematopoiesis; Infection; Irradiation; Thrombopoietin; Thrombosis

Indexed keywords

THROMBOPOIETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW TRANSPLANTATION; COLONY FORMATION; DRUG EFFECT; HEMATOPOIESIS; HISTOLOGY; INFECTION; IRRADIATION; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOSIS;

ANIMALS; BACTERIAL INFECTIONS; BIOLOGICAL MARKERS; BLOOD COAGULATION DISORDERS; BONE MARROW; BONE MARROW DISEASES; DISEASE SUSCEPTIBILITY; DRUG EVALUATION, PRECLINICAL; ENDOTOXEMIA; FIBRINOGEN; FIBRINOLYSIS; HEMORRHAGE; IMMUNOLOGIC DEFICIENCY SYNDROMES; LEUKOCYTE COUNT; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; PLATELET ACTIVATION; PLATELET COUNT; RADIATION INJURIES, EXPERIMENTAL; RECOMBINANT PROTEINS; RNA, MESSENGER; THROMBOPOIETIN; THROMBOSIS; WHOLE-BODY IRRADIATION;

BACTERIA (MICROORGANISMS);

EID: 0035166177     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(00)00624-X     Document Type: Article

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