Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice

Blood

Volumn 87, Issue 11, 1996, Pages 4544-4551

  Ku, Hsun ^b   Yonemura, Yuji ^b   Kaushansky, Kenneth ^b   Ogawa, Makio ^a  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; STEEL FACTOR; THROMBOPOIETIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL PROLIFERATION; HEMATOPOIETIC STEM CELL; HORMONE RECEPTOR INTERACTION; MEGAKARYOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTOPOIESIS;

EID: 0030039567     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.11.4544.bloodjournal87114544     Document Type: Article

References (38)

1. Ogawa M: Differentiation and proliferation of hematopoietic stem cells. Blood 81:2844, 1993
2. 0 periods and constant doubling rates of early pluripotent hemopoietic progenitors. J Cell Physiol 117:308, 1983
3. Kishi K, Ihle JN, Urdal DL, Ogawa M: Murine B-cell stimulatory factor-1 (BSF-1)/interleukin-4 (IL-4) is a multilineage colony-stimulating factor that acts directly on primitive hemopoietic progenitors. J Cell Physiol 139:463, 1989
4. Koike K, Ogawa M, Ihle JN, Miyake T, Shimizu T, Miyajima A, Yokota T, Arai K: Recombinant murine granulocyte-macrophage (GM) colony-stimulating factor supports formation of GM and multipotential blast cell colonies in culture: Comparison with the effects of interleukin-3. J Cell Physiol 131:458, 1987
5. Leary AG, Yang YC, Clark SC, Gasson JC, Golde DW, Ogawa M: Recombinant gibbon interleukin 3 supports formation of human multilineage colonies and blast cell colonies in culture: Comparison with recombinant human granulocyle-macrophage colony-stimulating factor. Blood 70:1343, 1987
6. Ikebuchi K, Wong GG, Clark SC, Ihle JN, Hirai Y, Ogawa M: Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci USA 84:9035, 1987
7. Musashi M, Yang YC, Paul SR, Clark SC, Sudo T, Ogawa M: Direct and synergistic effects of interleukin 11 on murine hemopoiesis in culture. Proc Natl Acad Sci USA 88:765, 1991
8. Ikebuchi K, Clark SC, Ihle JN, Souza LM, Ogawa M: Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors. Proc Natl Acad Sci USA 85:3445, 1988
9. Leary AG, Wong GG, Clark SC, Smith AG, Ogawa M: Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells. Blood 75:1960, 1990
10. 0 and entry into the cell cycle of primitive human hemopoietic progenitors. Proc Natl Acad Sci USA 89:4013, 1992
11. Hirayama F, Katayama N, Neben S, Donaldson D, Nickbarg EB, Clark SC, Ogawa M: Synergistic interaction between interleukin-12 and steel factor in support of proliferation of murine lymphohematopoietic progenitors in culture. Blood 83:92, 1994
12. Jacobsen SE, Veiby OP, Smeland EB: Cytotoxic lymphocyte maturation factor (interleukin 12) is a synergistic growth factor for hematopoietic stem cells. J Exp Med 178:413, 1993
13. Tsuji K, Zsebo KM, Ogawa M: Enhancement of murine blast cell colony formation in culture by recombinant rat stem cell factor, ligand for c-kit. Blood 78:1223, 1991
14. Tsuji K, Lyman SD, Sudo T, Clark SC, Ogawa M: Enhancement of murine hematopoiesis by synergistic interactions between steel factor (ligand for c-kit), interleukin-11, and other early acting factors in culture. Blood 79:2855, 1992
15. Hirayama F, Lyman SD, Clark SC, Ogawa M: The FLT3 ligand supports proliferation of lymphohemopoietic progenitors and early B-lymphoid progenitors. Blood 85:1762, 1995
16. de Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang WJ, Oles KJ, Hultgren B, Solberg Jr LA, Goeddel DV, Eaton DL: Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369:533, 1994
17. Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton-Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, Bell LA, Sprecher CA, Blumberg H, Johnson R, Prunkard D, Ching AFT, Mathewes SL, Bailey MC, Forstrom JW, Buddle MM, Osborn SG, Evans SJ, Sheppard PO, Presnell SR, O'Hara PJ, Hagen FS, Roth GJ, Foster DC: Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369:565, 1994
18. Kaushansky K, Lok S, Holly RD, Broudy VC, Lin N, Bailey MC, Forstrom JW, Buddle MM, Oort PJ, Hagen FS, Roth GJ, Papayannopoulou T, Foster DC: Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature 369:568, 1994
19. Wendung F, Maraskovsky E, Debili N, Florindo C, Teepe M, Titeux M, Methia N, Breton-Gorius J, Cosman D, Vainchenker W: cMpl ligand is a humoral regulator of megakaryocytopoiesis. Nature 369:571, 1994
20. Foster DC, Sprecher CA, Grant FJ, Kramer JM, Kuijper JL, Holly RD, Whitmore TE, Heipel MD, Bell LA, Ching AFT, McGrane V, Hart C, O'Hara PJ, Lok S: Human thrombopoietin: Gene structure, cDNA sequence, expression, and chromosomal localization. Proc Natl Acad Sci USA 91:13023, 1994
21. Bartley TD, Bogenberger J, Hunt P, Li Y-S, Lu HS, Martin F, Chang M-S, Samal B, Nichol JL, Swift S, Johnson MJ, Hsu R-Y, Parker VP, Suggs S, Skrine JD, Merewether LA, Clogston C, Hsu E, Hokom MM, Hornkohl A, Choi E, Pangelinan M, Sun Y, Mar V, McNinch J, Simonet L, Jacobsen F, Xie C, Shutter J, Chute H, Basu R, Selander L, Trollinger D, Sieu L, Padilla D, Trail G, Elliott G, Izumi R, Covey T, Crouse J, Garcia A, Xu W, Del Castillo J, Biron J, Cole S, Hu MC-T, Pacifici R, Ponting I, Saris C, Wen D, Yung YP, Lin H, Bosselman RA: Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell 77:1117, 1994
22. Broudy VC, Lin NL, Kaushansky K: Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood 85:1719, 1995
23. Shin JP, Zeng HQ, Ogawa M: Enrichment of murine marrow cells for progenitors of multilineage hematopoietic colonies. Leukemia 6:193, 1992
24. Ortega G, Korty PE, Shevach EM, Malek TR: Role of Ly-6 in lymphocyte activation. I. Characterization of a monoclonal antibody to a nonpolymorphic Ly-6 specificity. J Immunol 137:3240, 1986
25. Nishikawa S, Kusakabe M, Yoshinaga K, Ogawa M, Hayashi S, Kunisada T, Era T, Sakakura T, Nishikawa S-I: In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: Two distinct waves of c-kit-dependency during melanocyte development. EMBO J 10:2111, 1991
26. Nakahata T, Ogawa M: Clonal origin of murine hemopoietic colonies with apparent restriction to granulocyte-macrophage-megakaryocyte (GMM) differentiation. J Cell Physiol 111:239, 1982
27. Nakahata T, Ogawa M: Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies. Proc Natl Acad Sci USA 79:3843, 1982
28. Suda T, Suda J, Ogawa M: Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations. Proc Natl Acad Sci USA 80:6689, 1983
29. Katayama N, Shih JP, Nishikawa S, Kina T, Clark SC, Ogawa M: Stage-specific expression of c-kit protein by murine hematopoietic progenitors. Blood 82:2353, 1993
30. Heinrich MC, Dooley DC, Freed AC, Band L, Hoatlin ME, Keeble WW, Peters ST, Silvey KV, Ey FS, Rabat D, Maziarz RT, Bagby GC Jr: Constitutive expression of steel factor gene by human stromal cells. Blood 82:771, 1993
31. Langley KE, Bennett LG, Wypych J, Yancik SA, Liu X-D, Westcott KR, Chang DG, Smith KA, Zsebo KM: Soluble stem cell factor in human serum. Blood 81:656, 1993
32. Katayama N, Clark SC, Ogawa M: Growth factor requirement for survival in cell-cycle dormancy of primitive murine lymphohematopoietic progenitors. Blood 81:610, 1993
33. Yonemura Y, Ku H, Hirayama F, Ogawa M: IL-3 or IL-1 abrogates the reconstituting ability of hematopoietic stem cells. Exp Hematol 23:899, 1995 (abstr)
34. Methia N, Louache F, Vainchenker W, Wendung F: Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis. Blood 82:1395, 1993
35. Berardi AC, Wang A, Levine JD, Lopez P, Scadden DT: Functional isolation and characterization of human hematopoietic stem cells. Science 267:104, 1995
36. Zeigler FC, de Sauvage F, Widmer HR, Keller GA, Donahue C, Schreiber RD, Malloy B, Mass P, Eaton D, Matthews W: In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells. Blood 84:4045, 1994
37. Kobayashi M, Laver JH, Kato T, Miyazaki H, Ogawa M: Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood 86:2494, 1995
38. Kaushansky K, Broudy VC, Grossman A, Humes J, Lin N, Ren HP, Bailey MC, Papayannopoulou T, Forstrom JW, Sprugel KH: Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy. J Clin Invest 96:1683, 1995