Combined administration of recombinant human megakaryocyte growth and development factor and granulocyte colony-stimulating factor enhances multilineage hematopoietic reconstitution in nonhuman primates after radiation-induced marrow aplasia

Journal of Clinical Investigation

Volumn 97, Issue 9, 1996, Pages 2145-2151

  Farese, Ann M ^a,b   Hunt, Pamela ^c   Grab, Lisa B ^a,b   MacVittie, Thomas J ^a,b  

^a ARMED FORCES RADIOBIOLOGY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

^c AMGEN INC   (United States)

Author keywords

Cytokines; Platelet count; Primates; Radiation; Thrombocytopenia

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR DERIVATIVE; HEMOPOIETIC GROWTH FACTOR; HUMAN ALBUMIN; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW APLASIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MIXTURE; HEMATOPOIESIS; NEUTROPENIA; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; RHESUS MONKEY; THROMBOCYTOPENIA; WHOLE BODY RADIATION;

ANIMALS; CELL LINEAGE; COLONY-FORMING UNITS ASSAY; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; HUMANS; MACACA MULATTA; MALE; MEGAKARYOCYTES; RADIATION INJURIES, EXPERIMENTAL; RECOMBINANT PROTEINS; THROMBOPOIETIN; WHOLE-BODY IRRADIATION;

EID: 0029963122     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118652     Document Type: Article

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