Section 1: β-cell differentiation and growth: Developmental biology of the pancreas

Diabetes

Volumn 50, Issue SUPPL. 1, 2001, Pages

  Edlund, Helena ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; FOLLISTATIN; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; CELL DIFFERENTIATION; CELL GROWTH; CELL TYPE; CONFERENCE PAPER; EMBRYO; EMBRYO DEVELOPMENT; INSULIN DEPENDENT DIABETES MELLITUS; MATURITY ONSET DIABETES MELLITUS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 0035129044     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (57)

1. The neural crest and the origin of the insulin-producing and other gastrointestinal hormone producing cells
2. Analysis of endoderm formation in the avian blastoderm by the use of quail-chick chimaeras: The problem of the neurectodermal origin of the cells of the APUD series
3. The β cell transcription factors and the development of the pancreas
4. Transcribing pancreas
5. Pancreas development and diabetes
6. The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
7. Insulin-promoter-factor 1 is required for pancreas development in mice
8. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
9. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
10. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
11. On the origin of pancreatic endocrine cells
12. Independent requirement for ISL1 in the formation of the pancreatic mesenchyme and islet cells
13. Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation
14. Conversion of Xenopus into neurons by NeuroD, a basic helix-loop-helix protein
15. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice
16. NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus
17. The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
18. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
19. Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas
20. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
21. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
22. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling
23. Development of the embryonic endocrine pancreas
24. Neurogenic genes and vertebrate neurogenesis
25. Notch and neurogenesis
26. Epitheliomesenchymal interaction in pancreatic morphogenesis
27. Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
28. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
29. Early pancreas organogenesis: Morphogenesis, tissue interactions and mass effects
30. Developmental biology of the pancreas
31. Notochord to endoderm signalling is required for pancreas development
32. Notochord repression of endodermal Sonic hedgehog permits pancreas development
33. Pancreas development is promoted by cyclopamine, a Hedgehog signaling inhibitor
34. The development of the dorsal and ventral mammalian pancreas in vivo and in vitro
35. A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues
36. Selective agenesis of the dorsal pancreas in nu̇ce lacking homeobox gene Hlxb9
37. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
38. Neurogenin1 is essential for the deternu̇nation of neuronal precursors for proximal cranial sensory ganglia
39. The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons
40. Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS
41. Notch-signalling controls pancreatic cell differentiation
42. The Notch 3 intracellular domain represses Notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters
43. Control of endodermal endocrine development by Hes-1
44. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
45. Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreas development
46. Fibroblast growth factor 2 promotes pancreatic epithelial cell proliferation via functional fibroblast growth factor receptors during embryonic life
47. Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas
48. β-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes
49. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
50. Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes
51. Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus
52. Mutations in the hepatocyte nuclear factor-4 alpha gene in maturity-onset diabetes of the young
53. Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young
54. Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY
55. Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
56. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus
57. The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes