Molecular regulation of lung development

Annual Review of Physiology

Volumn 63, Issue , 2001, Pages 471-494

  Cardoso, W V ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Branching morphogenesis; Fibroblast growth factors; Organogenesis; Pattern formation; Retinoids

Indexed keywords

FIBROBLAST GROWTH FACTOR; RETINOIC ACID; RETINOID; SONIC HEDGEHOG PROTEIN; TRANSFORMING GROWTH FACTOR;

CELL INTERACTION; EMBRYO PATTERN FORMATION; EPITHELIUM; HUMAN; LUNG ALVEOLUS; LUNG DEVELOPMENT; MESENCHYME CELL; MORPHOGENESIS; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; RESPIRATORY SYSTEM; REVIEW; TRACHEOBRONCHIAL TREE;

ANIMALS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LUNG; MICE;

EID: 0035052815     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.63.1.471     Document Type: Review

References (130)

1. HNF-3β is essential for node and notochord formation in mouse development
2. Fgfr2 is required for limb outgrowth and lung branching morphogenesis
3. Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects
4. Evidence from normal expression and targeted misexpression that Bone Morphogenetic Protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis
5. Involvement of Sonic Hedgehog (Shh) in mouse embryonic lung growth and morphogenesis
6. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung
7. Identification of Hox genes in newborn lung and effects of gestational age and retinoic acid on their expression
8. 2-exposed rat lung
9. Transcription factors and pattern formation in the developing lung
10. Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro
11. Retinoic acid alters the expression of pattern-related genes in the developing rat lung
12. FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium
13. A decade of molecular biology of retinoic acid receptors
14. Retinoic acid is required in the mouse embryo for left-right asymmetry determination and heart morphogenesis
15. Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry
16. Members of the HNF3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B
17. Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene
18. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo
19. An important role for the glb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
20. Temporally-regulated retinoic acid depletion produces specific neural crest, ocular and nervous defects
21. Retinoic acid receptors and cellular retinoid binding proteins. I. Asystematic study of their differential pattern of transcription during mouse organogenesis
22. Developmental expression of murine retinoid X receptor (RXR) genes
23. Submucosal gland development in the airway is controlled by Lymphoid Enhancer Binding Factor 1 (LEF1)
24. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
25. Progenitor cells of the adult human airway involved in submucosal gland development
26. Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing meuse embryos
27. EGF and TGF alpha influence in vitro lung development by induction of matrix-degrading metalloproteinases
28. High frequency of retinoic acid receptor beta abnormalities in human lung cancer
29. Cellular retinol-binding protein I is essential for vitamin A homeostasis
30. Evidence for the involvement of the Gli gene family in embryonic mouse lung development
31. Epithelial morphogenesis
32. Keratinocyte growth factor is required for hair development but not wound healing
33. Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory system and reproductive epithelium
34. sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
35. Notochord repression of endodermal Sonic hedgehog permits pancreas development
36. Colocalization of TGF-β1 and collagen I and III, fibronectin, and glycosaminoglycans during lung branching morphogenesis
37. Epithelial-mesenchymal interactions in the pathogenesis of asthma
38. Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development
39. Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
40. Characterization of recombinant human fibroblast growth factor (FGF)-10 reveals functional similarities with keratinocyte growth factor (FGF-7)
41. Transducing Hedgehog: The story so far
42. A molecular basis for retinoic acid-induced axial truncation
43. Initiation of mammalian liver development from endoderm by fibroblast growth factors
44. The lipid interstitial cell of the pulmonary alveolus: Age and species differences
45. Hox genes in the lung
46. Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development
47. Notochord to endoderm signaling is required for pancreas development
48. The T/ebp null mouse thyroid-specific enhancer binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain and pituitary
49. BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice
50. GATA-4 transcription factor is required for ventral morphogenesis and heart tube formation
51. Mice deficient in cellular retinoic acid binding protein II (CRABPII) or in both CRABPI and CRABPII are essentially normal
52. Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer
53. Fibroblast growth factor interactions in the developing lung
54. Maternal rescue of transforming growth factor-beta 1 null mice
55. Sonic hedgehog is essential to foregut development
56. Regulation of retinoic acid signaling during lung morphogenesis
57. The roles of FGFs in the early development of vertebrate limbs
58. TGFβ signal transduction
59. Postnatal treatment with retinoic acid increases the number of pulmonary alveoli in rats
60. Retinoic acid treatment abrogates elastase-induced pulmonary emphysema in rats
61. Retinoic acid treatment partially rescues failed septation in rats and in mice
62. FGF-2 induces surfactant protein gene expression in fetal rat lung epithelial cells through a MAPK-independent pathway
63. Retinoids, retinoic acid receptors, and cytoplasmic retinoid binding proteins in perinatal rat lung fibroblasts
64. The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development
65. Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants
66. Role of transcription factors in fetal lung development and surfactant protein gene expression
67. Lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal
68. Genetic control of branching morphogenesis
69. Retinoic acid differentially regulates expression of surfactant-associated proteins in human fetal lung
70. Embryogenesis of tracheal atresia
71. Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branche less
72. Defects in tracheoesophageal and lung morphogenesis in Nkx2.1 (-/-) mouse embryos
73. Vertebrate sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
74. Stage-dependent responses of the developing lung to retinoic acid signaling
75. Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 α, β, and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm
76. GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo
77. Dynamic pattern of retinoic acid synthesis and response in the developing mammalian heart
78. Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus
79. Ptch 2, a second mouse Patched gene is co-expressed with Sonic hedgehog
80. Restricted expression and retinoic-induced down-regulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development
81. Embryonic retinoic acid synthesis is essential for early mouse postimplantation development
82. Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture
83. Bud formation precedes the appearance of differential cell proliferation during branching morphogenesis of mouse lung epithelium in vitro
84. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
85. Regulation of Hoxa4 and Hoxa5 genes in the embryonic mouse lung by retinoic acid and TGF-β1: Implications for lung development and patterning
86. FGF- 10 is a chemotactic factor for distal epithelial buds during lung development
87. Mouse Glil mutants are viable but have defects in SHH signaling in combination with Gli2 mutation
88. In situ hybridization analysis of TGF-β 3 RNA expression during mouse development: Comparative studies with TGF-β1 and 2
89. Sonic hedgehog regulates branching morphogenesis in the mammalian lung
90. Molecular mechanisms controlling lung morphogenesis
91. Two FGF receptors are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis
92. Clara cells
93. Keratinocyte growth factor and its receptor are involved in regulating early lung branching
94. Human fetal lung development and related animal models
95. Mouse preproepidermal growth factor synthesis by the kidney and other tissues
96. Expression of a retinoic acid response element-hsp LacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis
97. Fgf-10 is essential for limb and lung formation
98. pRb is necessary for inhibition of N-myc expression by TGFβ-1 in embryonic lung organ cultures
99. Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme
100. Induction of alveolar type II cell differentiation in embryonic tracheal epithelium in mesenchyme-free culture
101. Vitamin A status of neonates with bronchopulmonary dysplasia
102. Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung
103. Identification, cellular localization, isolation and characterization of human Clara cell-specific 10 kD protein
104. A tandem duplication within the fibrillin-1 gene is associated with the mouse tight skin syndrome
105. Mammalian lung development: Interactions in primordium formation and bronchial morphogenesis
106. Keratinocyte growth factor increases mRNAs for SP-A and SP-B in adult rat alveolar type II cells in culture
107. Breathless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching
108. Fibroblast growth factors as multifunctional signaling factors
109. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis
110. The development of lung in mammals: An analysis of concepts and findings
111. Development and distribution of mucous glands in the fetal human trachea
112. HNF3/forkhead homologue-4 influences lung morphogenesis and respiratory epithelial cell differentiation in vivo
113. Conditional expression of fibroblast growth factor-7 in the developing and mature lung
114. Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): Coming of age
115. Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo
116. Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: Important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid
117. Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development
118. Bmp-4 and fgf10 play opposing roles during lung bud morphogenesis
119. Vertebrate endoderm development Annu
120. The winged-helix transcription factor HNF3β is required for notochord development in the mouse embryo
121. Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice
122. Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase
123. Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabohsm
124. An analysis of the syndrome of malformation induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation
125. Structure and expression of the rat mRNA encoding a novel member of the fibroblast growth factor family
126. The tracheoesophageal septum-Fact or fantasy?
127. The postnatal development and growth of the human lung: II. Morphology
128. Abrogation of transforming growth factor beta type II receptor stimulates embryonic mouse lung branching morphogenesis in culture
129. Molecular identification of a major retinoic acid synthesizing enzyme: A retinaldehyde-specific dehydrogenase
130. Arrested lung morphogenesis in transgenic mice beating an SP-C-TGF-β 1 chimeric gene