Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis

Development

Volumn 124, Issue 1, 1997, Pages 53-63

  Bellusci, Savério ^a   Furuta, Yasuhide ^a   Rush, Margaret G ^a   Henderson, Randall ^a   Winnier, Glenn ^a   Hogan, Brigid L M ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

Bmp4; Lung development; Mouse embryo; Ptc; Shh; Transgenic overexpression

Indexed keywords

BROXURIDINE; LUNG SURFACTANT; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN C; SONIC HEDGEHOG PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; ELECTRON MICROSCOPY; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; EPITHELIUM CELL; GENE EXPRESSION; LUNG ALVEOLUS; LUNG DEVELOPMENT; MESENCHYME; MICROSCOPY; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSGENIC MOUSE;

ANIMALS; DNA PRIMERS; DROSOPHILA; EMBRYONIC AND FETAL DEVELOPMENT; EMBRYONIC INDUCTION; ENHANCER ELEMENTS (GENETICS); EPITHELIAL CELLS; EPITHELIUM; FEMALE; HEDGEHOG PROTEINS; IN SITU HYBRIDIZATION; LIVER; LUNG; MESODERM; MICE; MICE, TRANSGENIC; MORPHOGENESIS; POLYMERASE CHAIN REACTION; PREGNANCY; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; PROTEINS; PROTEOLIPIDS; PULMONARY SURFACTANTS; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 0031034866     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Alcedo, J., Ayzenzon, M., Von Ohlen, T., Noll, M. and Hooper, J. E. (1996). The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal. Cell 86, 221-232.
2. Alescio, T. and Cassini, A. (1962). Induction in vitro of tracheal buds by pulmonary mesenchyme grafted on tracheal epithelium. J. Exp. Zool. 150, 83-94.
3. Basler, K. and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
4. Bellusci, S., Henderson, R., Winnier, G., Oikawa, T. and Hogan, B. L. M. (1996). Evidence from normal expression and targeted misexpression that Bone Morphogenetic Protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development 122, 1693-1702.
5. Bitgood, M. J. and McMahon, A. P. (1995). Hedgehog and Bmp genes are co-expressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 172, 126-138.
6. Capdevila, J., Pariente, F., Sampedro, J., Alonso, J. L. and Guerrero, I. (1994). Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos. Development 120, 987-998.
7. Chirgwin, J. M., Pryzbyla, A. E., MacDonald, R. J. and Rutter, W. J. (1979). Isolation of biologically active ribonucleic acid from sources enriched with ribonuclease. Biochemistry 18, 5294-5299.
8. Diaz-Benjumea, F. J., Cohen, B. and Cohen, S. M. (1994). Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs. Nature 372, 175-179.
9. Fan, C.-M., Porter, J. A., Chiang, C., Chang, D. T., Beachy, P. A. and Tessier-Lavigne, M. (1995). Long range sclerotome induction by Sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signalling pathway. Cell 81, 457-465.
10. Forbes, A. J., Lin, H., Ingham, P. and Spradling, A. C. (1996). Hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila. Development 121, 1125-1135.
11. Goldin, G. V. and Wessels, N. K. (1979). Mammalian lung development: the possible role of cell proliferation in the formation of supernumerary tracheal buds and in branching morphogenesis. J. Exp. Zool. 208, 337-346.
12. Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A. and Scott, M. P. (1996) Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by hedgehog. Genes Dev. 10, 301-312.
13. Green, M. C. (1968). Mechanism of the pleiotropic effects of the short ear mutant gene in the mouse. J. Exp. Zool. 167, 129-150.
14. Herberlein, U., Wolff, T. and Rubin, G. M. (1993). The TGFβhomolog Dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in Drosophila retina. Cell 75, 913-926.
15. Hogan, B. L. M., Beddington, R., Constantini, F. and Lacy, E. (1994). Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
16. Hooper, J. E. (1994) Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos. Nature 372, 461-464.
17. Hooper, J. E. and Scott, M. P. (1989) The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 59, 751-765.
18. Hui, C. C. Slusarski, D. Platt, K. A. Holmgren, R. and Joyner A. L. (1994) Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm-and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev. Biol. 162, 402-13
19. Ingham, P. W. (1993) Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo. Nature 366, 560-562.
20. Ingham, P. W., Taylor, A. M. and Nakano, Y. (1991). Role of the Drosophila patched gene in positional signalling. Nature 353, 184-187.
21. Johnson, R. L., Rothman, A. L., Xie, J., Goodrich, L. V., bare, J. W., Bonifas, J. M., Quinn, A. G., Myers, R. M., Cox, D. R., Epstein, E. H. and Scott, M. P. (1996). Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272, 1668-1671.
22. Kaartinen, V., Voncken, J. W., Shuler, C., Warburton, D., Bu, D., Heisterkamp, N. and Groffen, J. (1995). Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelialmesenchymal interaction. Nature Genetics 11, 415-421.
23. Kalina, M., Mason, R. J. and Shannon, J. M. (1992). Surfactant protein C is expressed in alveolar type II cells but not in Clara cells of rat lung. Am. J. Respir. Cell Mol. Biol. 6, 594-600.
24. King, J. A., Marker, P. C., Seung, K. J. and Kingsley, D. M. (1994). BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice. Dev. Biol. 166, 112-122.
25. Korfhagen, T., Glasser, S., Wert, S., Bruno, M., Daugherty, C., McNeish, J., Stock, J., Potter, S. and Whitsett, J. (1990). Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice. Proc. Natl. Acad. Sci. USA 87, 6122-6126.
26. Kulkarni, A. B., Huh, C., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M. and Karlsson, S. (1993). Transforming growth factor-beta1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA90, 770-774.
27. Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. and Tabin, C. (1994). Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.
28. Lepage, T., Cohen, S. M., Diaz-Benjumea, F. J. and Parkhurst, S. M. (1995) Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning. Nature 373, 711-715.
29. Marigo, V., Scott, M. P., Johnson, R. L., Goodrich, L. V. and Tabin, C. J. (1996) Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development 122, 1225-1233.
30. Nakano, Y., Guerrero, I., Hidalgo, A., Taylor, A., Whittle, J. R. S. and Ingham, P. W. (1989). A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature 341, 508-513.
31. Peters, K., Werner, S., Liao, X., Wert, S., Whitsett, J. and Williams, L. (1994). Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J. 13, 3296-3301.
32. Roberts, D. J., Johnson, R. L., Burke, A. C., Nelson, C. E., Morgan, B. A. and Tabin, C. (1995). Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 121, 3163-3174.
33. Sakai, Y., Nelson, K. G., Snedeter, S., Bossert, N. L., Walker, M. P., McMahon, J. and DiAugustine, R. P. (1994). Expression of epidermal growth factor in suprabasal cells of stratified squamous epithelia: implications for a role in differentiation. Cell Growth and Diff. 5, 527-535
34. Sasaki, H. and Hogan, B. L. M. (1993). Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development 118, 47-59.
35. Serra, R., Pelton, R. W. and Moses, H. L. (1994). TGFβ1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development 120, 2153-2161.
36. Shannon, J. M. (1994). Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme. Dev. Biol. 166, 600-614.
37. Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., Yin, M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., Annunziata, N. and Doetschman, T. (1992). Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359, 693-699.
38. Simonet, W. S., Derose, M. L., Bucay, N., Nguyen, H. Q., Wert, S. E., Zhou, L., Ulich, T. R., Thomason, A., Danilenko, D. M. and Whitsett, J. A. (1995). Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung. Proc. Natl. Acad. Sci. USA92, 12461-12465.
39. Singh, G., Katyal, S. L., Brown, W. E. and Kennedy, A. L. (1993). Mouse clara cell 10-kDa (CC10) protein: cDNA nucleotide sequence and molecular basis of variation in progesterone binding of CC10 from different species. Exp. Lung Research 19, 67-75.
40. Snouwaert, J. N., Brigman, K. K., Latour, A. M., Malouf, N. M., Boucher, R. C., Smithies, O. and Koller, B. H. (1992). An animal model for cystic fibrosis made by gene targeting. Science 257, 1083-1088.
41. Tabata, T. and Kornberg, T. (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginai discs. Cell 76, 89-102.
42. Ten Have-Opbroek, A. A. W. (1991). Lung development in the mouse embryo. Exp. Lung Research 17, 111-130.
43. Urase, K., Mukasa, T., Igarashi, H., Ishii, Y., Yasagi, S., Momoi, M. Y. and Momoi, T. (1996). Spatial expression of Sonic hedgehog in the lung epithelium during branching morphogenesis. Biochem. Biophys. Res. Comm. 225, 161-166.
44. Vanio, S., Karavanova, I., Jowett, A. and Thesleff, I. (1993). Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75, 45-58.
45. Wert, S., Glasser, S. W., Korfhagen, T. R. and Whitsett, J. A. (1993). Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev. Biol. 156, 426-443.
46. Wessels, N. K. (1970). Mammalian lung development: interactions in formation and morphogenesis of tracheal buds. J. Exp. Zool. 175, 455-466.
47. Winnier, G., Blessing, M., Labosky, P. A. and Hogan, B. (1995). Bone Morphogenetic protein-4 (BMP-4) is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105-2116.
48. Zhao, G.-Q., Zhou, X., Eberspaecher, H., Solursh, M. and de Crombrugghe, B. (1993). Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes. Proc. Natl. Acad. Sci. USA 90, 8633-8637.
49. Zhou, L., Dey, C. R., Wert, S. E. and Whitsett, J. A. (1996). Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-β1 chimeric gene. Dev. Biol. 175, 227-238.