메뉴 건너뛰기




Volumn 217, Issue 1, 2000, Pages 62-74

Regulation of the Hoxa4 and Hoxa5 genes in the embryonic mouse lung by retinoic acid and TGFβ1: Implications for lung development and patterning

Author keywords

Embryonic lung patterning; Hoxa4; Hoxa5; Retinoic acid; TGF 1

Indexed keywords

RETINOIC ACID; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0033986022     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(200001)217:1<62::AID-DVDY6>3.0.CO;2-U     Document Type: Article
Times cited : (50)

References (57)
  • 1
    • 0031573797 scopus 로고    scopus 로고
    • Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects
    • Aubin J, Lemieux M, Tremblay M, Berard J, Jeannotte L. 1997. Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects. Dev Biol 192:432-445.
    • (1997) Dev Biol , vol.192 , pp. 432-445
    • Aubin, J.1    Lemieux, M.2    Tremblay, M.3    Berard, J.4    Jeannotte, L.5
  • 2
    • 0031970429 scopus 로고    scopus 로고
    • Transcriptional interferences at the Hoxa4/Hoxa5 locus: Importance of correct Hoxa5 expression for the proper specification of the axial skeleton
    • Aubin J, Lemieux M, Tremblay M, Behringer RR, Jeannotte L. 1998. Transcriptional interferences at the Hoxa4/Hoxa5 locus: Importance of correct Hoxa5 expression for the proper specification of the axial skeleton. Dev Dyn 212:141-156.
    • (1998) Dev Dyn , vol.212 , pp. 141-156
    • Aubin, J.1    Lemieux, M.2    Tremblay, M.3    Behringer, R.R.4    Jeannotte, L.5
  • 3
    • 0027410147 scopus 로고
    • Sequences 5′ of the homeobox of the Hox-1.4 gene direct tissue-specific expression of lacZ during mouse development
    • Behringer RR, Crotty DA, Tennyson VM, Brinster RL, Palmiter RD, Wolgemuth DJ. 1993. Sequences 5′ of the homeobox of the Hox-1.4 gene direct tissue-specific expression of lacZ during mouse development. Development 117:823-833.
    • (1993) Development , vol.117 , pp. 823-833
    • Behringer, R.R.1    Crotty, D.A.2    Tennyson, V.M.3    Brinster, R.L.4    Palmiter, R.D.5    Wolgemuth, D.J.6
  • 4
    • 0029956078 scopus 로고    scopus 로고
    • Evidence from normal expression and targeted misexpression that Bone morphogenetic protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis
    • Bellusci S, Henderson R, Winnier G, Oikawa T, Hogan BLM. 1996. Evidence from normal expression and targeted misexpression that Bone morphogenetic protein-4 (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development 122:1693-1702.
    • (1996) Development , vol.122 , pp. 1693-1702
    • Bellusci, S.1    Henderson, R.2    Winnier, G.3    Oikawa, T.4    Hogan, B.L.M.5
  • 6
    • 0031457616 scopus 로고    scopus 로고
    • Fibroblast growth factor 10 and branching morphogenesis in the embryonic mouse lung
    • Bellusci S, Grindley J, Emoto H, Itoh N, Hogan BLM. 1997b. Fibroblast growth factor 10 and branching morphogenesis in the embryonic mouse lung. Development 124:4867-4878.
    • (1997) Development , vol.124 , pp. 4867-4878
    • Bellusci, S.1    Grindley, J.2    Emoto, H.3    Itoh, N.4    Hogan, B.L.M.5
  • 7
    • 0028275807 scopus 로고
    • Identification of Hox genes in newborn lung and effects of gestational age and retinoic acid on their expression
    • Bogue CW, Gross I, Vasavada H, Dynia DW, Wilson CM, Jacobs HC. 1994. Identification of Hox genes in newborn lung and effects of gestational age and retinoic acid on their expression. Am J Physiol 266:L448-L454.
    • (1994) Am J Physiol , vol.266
    • Bogue, C.W.1    Gross, I.2    Vasavada, H.3    Dynia, D.W.4    Wilson, C.M.5    Jacobs, H.C.6
  • 9
    • 0029304329 scopus 로고
    • Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro
    • Cardoso WV, Williams MC, Mitsialis SA, Joyce-Brady M, Rishi AK, Brody JS. 1995. Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro. Am J Respir Cell Mol Biol 12:464-476.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 464-476
    • Cardoso, W.V.1    Williams, M.C.2    Mitsialis, S.A.3    Joyce-Brady, M.4    Rishi, A.K.5    Brody, J.S.6
  • 10
    • 0028788008 scopus 로고
    • Transcription factors and pattern formation in the developing lung
    • Cardoso WV. 1995. Transcription factors and pattern formation in the developing lung. Am J Physiol 269:L429-L442.
    • (1995) Am J Physiol , vol.269
    • Cardoso, W.V.1
  • 11
    • 0029757358 scopus 로고    scopus 로고
    • Retinoic acid alters the expression of pattern-related genes in the developing rat lung
    • Cardoso WV, Mitsialis SA, Brody JS, Williams MC. 1996. Retinoic acid alters the expression of pattern-related genes in the developing rat lung. Dev Dyn 207:47-59.
    • (1996) Dev Dyn , vol.207 , pp. 47-59
    • Cardoso, W.V.1    Mitsialis, S.A.2    Brody, J.S.3    Williams, M.C.4
  • 12
    • 0031051868 scopus 로고    scopus 로고
    • FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium
    • Cardoso WV, Itoh A, Nogawa H, Mason I, Brody JS. 1997. FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium. Dev Dyn 208:398-405.
    • (1997) Dev Dyn , vol.208 , pp. 398-405
    • Cardoso, W.V.1    Itoh, A.2    Nogawa, H.3    Mason, I.4    Brody, J.S.5
  • 14
    • 0026633493 scopus 로고
    • The lungs and vitamin A
    • Chytil F. 1992. The lungs and vitamin A. Am J Physiol 262:517-527.
    • (1992) Am J Physiol , vol.262 , pp. 517-527
    • Chytil, F.1
  • 15
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S, Itoh S, Vivien D, Dijke P, Huet S, Gauthier J-M. 1998. Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 17:3091-3100.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Dijke, P.4    Huet, S.5    Gauthier, J.-M.6
  • 16
    • 0025685315 scopus 로고
    • Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogeneais
    • Dollé P, Ruberte E, Leroy P, Morriss-Kay G, Chambon P. 1990. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogeneais. Development 110:1133-1151.
    • (1990) Development , vol.110 , pp. 1133-1151
    • Dollé, P.1    Ruberte, E.2    Leroy, P.3    Morriss-Kay, G.4    Chambon, P.5
  • 17
    • 0024440624 scopus 로고
    • The mouse Hox-1.4 gene: Primary structure, evidence for promoter activity and expression during development
    • Galliot B, Dollé P, Vigneron M, Featherstone M, Baron A, Duboule D. 1989. The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development. Development 107:343-359.
    • (1989) Development , vol.107 , pp. 343-359
    • Galliot, B.1    Dollé, P.2    Vigneron, M.3    Featherstone, M.4    Baron, A.5    Duboule, D.6
  • 18
    • 0024432982 scopus 로고
    • Mouse homeo-genes within a subfamily, Hox-1.4, 2.6, and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation
    • Gaunt SL, Krumlauf R, Duboule D. 1989. Mouse homeo-genes within a subfamily, Hox-1.4, 2.6, and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation. Development 107:131-141.
    • (1989) Development , vol.107 , pp. 131-141
    • Gaunt, S.L.1    Krumlauf, R.2    Duboule, D.3
  • 19
    • 0032126768 scopus 로고    scopus 로고
    • Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway
    • Gould A, Itasaki N, Krumlauf R. 1998. Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway. Neuron 21:39-51.
    • (1998) Neuron , vol.21 , pp. 39-51
    • Gould, A.1    Itasaki, N.2    Krumlauf, R.3
  • 20
    • 0031693463 scopus 로고    scopus 로고
    • Epithelial/mesenchymal interactions and branching morphogenesis of the lung
    • Hogan BLM, Yingling JM. 1998. Epithelial/mesenchymal interactions and branching morphogenesis of the lung. Curr Opin Genet Dev 8:481-486.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 481-486
    • Hogan, B.L.M.1    Yingling, J.M.2
  • 22
    • 0029143166 scopus 로고
    • Compound mutants for the paralogous Hoxa-4, Hoxb-4, and Hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed
    • Horan GSB, Ramirez-Solis R, Featherstone M, Wolgemuth DJ, Bradley A, Behringer RR. 1995. Compound mutants for the paralogous Hoxa-4, Hoxb-4, and Hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed. Genes Dev 9:1667-1677.
    • (1995) Genes Dev , vol.9 , pp. 1667-1677
    • Horan, G.S.B.1    Ramirez-Solis, R.2    Featherstone, M.3    Wolgemuth, D.J.4    Bradley, A.5    Behringer, R.R.6
  • 23
  • 25
    • 0030982227 scopus 로고    scopus 로고
    • A sequence conserved in vertebrate Hox gene introns functions as an enhancer regulated by posterior homeotic genes in Drosophila imaginal discs
    • Keegan LP, Haerry TE, Crotty DA, Packer AI., Wolgemuth DJ, Gehring WJ. 1997. A sequence conserved in vertebrate Hox gene introns functions as an enhancer regulated by posterior homeotic genes in Drosophila imaginal discs. Mech Dev 63:145-157.
    • (1997) Mech Dev , vol.63 , pp. 145-157
    • Keegan, L.P.1    Haerry, T.E.2    Crotty, D.A.3    Packer, A.I.4    Wolgemuth, D.J.5    Gehring, W.J.6
  • 26
    • 0025941823 scopus 로고
    • Homeotic transformations of murine prevertebrae and concomitant alteration of Hox codes induced by retinoic acid
    • Kessel M, Gruss P. 1991. Homeotic transformations of murine prevertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 67:89-104.
    • (1991) Cell , vol.67 , pp. 89-104
    • Kessel, M.1    Gruss, P.2
  • 27
    • 0027953771 scopus 로고
    • Hox genes in vertebrate development
    • Krumlauf R. 1994. Hox genes in vertebrate development. Cell 78:191-201.
    • (1994) Cell , vol.78 , pp. 191-201
    • Krumlauf, R.1
  • 28
    • 0032908035 scopus 로고    scopus 로고
    • Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression
    • Larochelle C, Tremblay M, Bernier D, Aubin J, Jeannotte L. 1999. Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression. Dev Dyn 214:127-140.
    • (1999) Dev Dyn , vol.214 , pp. 127-140
    • Larochelle, C.1    Tremblay, M.2    Bernier, D.3    Aubin, J.4    Jeannotte, L.5
  • 30
    • 0029030722 scopus 로고
    • The role of Hoxa-3 in mouse thymus and thyroid development
    • Manley NR, Capecchi MR. 1995. The role of Hoxa-3 in mouse thymus and thyroid development. Development 121:1989-2003.
    • (1995) Development , vol.121 , pp. 1989-2003
    • Manley, N.R.1    Capecchi, M.R.2
  • 31
    • 0028073019 scopus 로고
    • Function of the retinoic acid receptors (RARs) during development. (II) multiple abnormalities at various stages of organogenesis in RAR double mutants
    • Mendelsohn C, Lohnes D, Decimo D, Lufkin T, LeMeur M, Chambon P, Mark M. 1994. Function of the retinoic acid receptors (RARs) during development. (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120:2749-2771.
    • (1994) Development , vol.120 , pp. 2749-2771
    • Mendelsohn, C.1    Lohnes, D.2    Decimo, D.3    Lufkin, T.4    LeMeur, M.5    Chambon, P.6    Mark, M.7
  • 34
    • 0026628060 scopus 로고
    • A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung
    • Moens CB, Auerbach AB, Conlon RA, Joyner AL, Rossant J. 1992. A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung. Genes Dev 6:691-704.
    • (1992) Genes Dev , vol.6 , pp. 691-704
    • Moens, C.B.1    Auerbach, A.B.2    Conlon, R.A.3    Joyner, A.L.4    Rossant, J.5
  • 35
    • 0030707641 scopus 로고    scopus 로고
    • Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung
    • Mollard R, Dziadek M. 1997. Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol 41:655-666.
    • (1997) Int J Dev Biol , vol.41 , pp. 655-666
    • Mollard, R.1    Dziadek, M.2
  • 36
    • 0031683165 scopus 로고    scopus 로고
    • Essential function of Gli2 and Gli3 in the formation of lung, trachea, and oesophagus
    • Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui C. 1998. Essential function of Gli2 and Gli3 in the formation of lung, trachea, and oesophagus. Nature Genet 20:54-57.
    • (1998) Nature Genet , vol.20 , pp. 54-57
    • Motoyama, J.1    Liu, J.2    Mo, R.3    Ding, Q.4    Post, M.5    Hui, C.6
  • 37
    • 0028943805 scopus 로고
    • Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture
    • Nogawa H, Ito T. 1995. Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture. Development 121: 1015-1022.
    • (1995) Development , vol.121 , pp. 1015-1022
    • Nogawa, H.1    Ito, T.2
  • 38
    • 0031922793 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development
    • Ohmichi H, Koshimizu U, Matsumoto K, Nakamura T. 1998. Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development. Development 125:1315-1324.
    • (1998) Development , vol.125 , pp. 1315-1324
    • Ohmichi, H.1    Koshimizu, U.2    Matsumoto, K.3    Nakamura, T.4
  • 39
    • 0030739085 scopus 로고    scopus 로고
    • N-cadherin protein distribution in normal embryos and in embryos carrying mutations in the homeobox gene Hoxa-4
    • Packer AI, Elwell VA., Parnass JD, Knudsen KA, Wolgemuth DJ. 1997. N-cadherin protein distribution in normal embryos and in embryos carrying mutations in the homeobox gene Hoxa-4. Int J Dev Biol 41:459-468.
    • (1997) Int J Dev Biol , vol.41 , pp. 459-468
    • Packer, A.I.1    Elwell, V.A.2    Parnass, J.D.3    Knudsen, K.A.4    Wolgemuth, D.J.5
  • 40
    • 0031835078 scopus 로고    scopus 로고
    • Expression of the murine Hoxa4 gene requires both autoregulation and a conserved retinoic acid response element
    • Packer AI, Crotty DA, Elwell VA, Wolgemuth DJ. 1998. Expression of the murine Hoxa4 gene requires both autoregulation and a conserved retinoic acid response element. Development 125:1991-1998.
    • (1998) Development , vol.125 , pp. 1991-1998
    • Packer, A.I.1    Crotty, D.A.2    Elwell, V.A.3    Wolgemuth, D.J.4
  • 41
    • 0032530644 scopus 로고    scopus 로고
    • FGF-10 is a chemotactic factor for distal epithelial buds during lung development
    • Park WY, Miranda B, Lebeche D, Hashimoto G, Cardoso WV. 1998. FGF-10 is a chemotactic factor for distal epithelial buds during lung development. Dev Biol 201:125-134.
    • (1998) Dev Biol , vol.201 , pp. 125-134
    • Park, W.Y.1    Miranda, B.2    Lebeche, D.3    Hashimoto, G.4    Cardoso, W.V.5
  • 42
    • 0032563948 scopus 로고    scopus 로고
    • Sonic hedgehog regulates branching morphogenesis in the mammalian lung
    • Pepicelli CV, Lewis PM, McMahon AP. 1998, Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol 8:1083-1086.
    • (1998) Curr Biol , vol.8 , pp. 1083-1086
    • Pepicelli, C.V.1    Lewis, P.M.2    McMahon, A.P.3
  • 43
    • 0028875032 scopus 로고
    • Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut
    • Roberts DJ, Johnson RL, Burke AC, Nelson CE, Morgan BA, Tabin CJ. 1995. Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 121:3163-3174.
    • (1995) Development , vol.121 , pp. 3163-3174
    • Roberts, D.J.1    Johnson, R.L.2    Burke, A.C.3    Nelson, C.E.4    Morgan, B.A.5    Tabin, C.J.6
  • 44
    • 0027514955 scopus 로고
    • Retinoic acid stimulates mouse lung development by a mechanism involving epithelial-mesenchymal interaction and regulation of epidermal growth factor receptors
    • Schuger L, Varani J, Mitra Jr. R, Gilbride K. 1993. Retinoic acid stimulates mouse lung development by a mechanism involving epithelial-mesenchymal interaction and regulation of epidermal growth factor receptors. Dev Biol 159:462-473.
    • (1993) Dev Biol , vol.159 , pp. 462-473
    • Schuger, L.1    Varani, J.2    Mitra R., Jr.3    Gilbride, K.4
  • 45
    • 0031874066 scopus 로고    scopus 로고
    • Analysis of Hox gene expression during early avian heart development
    • Searcy R, Yutzey K. 1998. Analysis of Hox gene expression during early avian heart development. Dev Dyn 213:82-91.
    • (1998) Dev Dyn , vol.213 , pp. 82-91
    • Searcy, R.1    Yutzey, K.2
  • 46
    • 0028168129 scopus 로고
    • TGFbeta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures
    • Serra R., Pelton RW, Moses HL. 1994. TGFbeta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. Development 120:2153-2161.
    • (1994) Development , vol.120 , pp. 2153-2161
    • Serra, R.1    Pelton, R.W.2    Moses, H.L.3
  • 47
    • 0031904040 scopus 로고    scopus 로고
    • Mesenchyme specifies epithelial differentiation in reciprocal recombinants of embryonic lung and trachea
    • Shannon JM, Nielsen LD, Gebb SA, Randell SH. 1998. Mesenchyme specifies epithelial differentiation in reciprocal recombinants of embryonic lung and trachea. Dev Dyn 212:482-494.
    • (1998) Dev Dyn , vol.212 , pp. 482-494
    • Shannon, J.M.1    Nielsen, L.D.2    Gebb, S.A.3    Randell, S.H.4
  • 48
    • 0026731121 scopus 로고
    • Vitamin A supplementation and bronchopulmonary dysplasia - Revisited
    • Shenai JP, Rush MG, Stahlman MT, Chytil F. 1992. Vitamin A supplementation and bronchopulmonary dysplasia - revisited. J Pediatr 121:399-401.
    • (1992) J Pediatr , vol.121 , pp. 399-401
    • Shenai, J.P.1    Rush, M.G.2    Stahlman, M.T.3    Chytil, F.4
  • 49
    • 0025968503 scopus 로고
    • Lung development in the mouse embryo
    • Ten Have-Opbroek AAW. 1991. Lung development in the mouse embryo. Exp Lung Res 17:111-130.
    • (1991) Exp Lung Res , vol.17 , pp. 111-130
  • 50
  • 52
    • 0031468415 scopus 로고    scopus 로고
    • Hoxb-5 expression in the developing mouse lung suggests a role in branching morphogenesis and epithelial cell fate
    • Volpe MV, Martin A, Vosatka RJ, Mazzoni CL, Nielsen HC. 1997. Hoxb-5 expression in the developing mouse lung suggests a role in branching morphogenesis and epithelial cell fate. Histochem Cell Biol 108:495-504.
    • (1997) Histochem Cell Biol , vol.108 , pp. 495-504
    • Volpe, M.V.1    Martin, A.2    Vosatka, R.J.3    Mazzoni, C.L.4    Nielsen, H.C.5
  • 53
    • 0027394563 scopus 로고
    • Conservation and divergence of patterns of expression and lineage-specific transcripts in orthologues and paralogues of the mouse Hox-1.4 gene
    • Watrin F, Wolgemuth DJ. 1993. Conservation and divergence of patterns of expression and lineage-specific transcripts in orthologues and paralogues of the mouse Hox-1.4 gene. Dev Biol 156:136-145.
    • (1993) Dev Biol , vol.156 , pp. 136-145
    • Watrin, F.1    Wolgemuth, D.J.2
  • 54
    • 0014905461 scopus 로고
    • Mammalian lung development: Interactions in formation and morphogenesis of tracheal buds
    • Wessells NK. 1970. Mammalian lung development: Interactions in formation and morphogenesis of tracheal buds. J Exp Zool 175:455-466.
    • (1970) J Exp Zool , vol.175 , pp. 455-466
    • Wessells, N.K.1
  • 55
    • 0000019122 scopus 로고
    • In situ hybridization
    • Stern CD, Holland PWH, editors. New York: Oxford University Press. p
    • Wilkinson DG. 1993. In situ hybridization. In: Stern CD, Holland PWH, editors. Essential developmental biology: a practical approach. New York: Oxford University Press. p 257-274.
    • (1993) Essential Developmental Biology: A Practical Approach , pp. 257-274
    • Wilkinson, D.G.1
  • 56
    • 0030602054 scopus 로고    scopus 로고
    • Abrogation of transforming growth factor-β type II receptor stimulates embryonic mouse lung branching morphogenesis in culture
    • Zhao J, Bu D, Lee M, Slavkin HC, Hall FL, Warburton D. 1996. Abrogation of transforming growth factor-β type II receptor stimulates embryonic mouse lung branching morphogenesis in culture. Dev Biol 180:242-257.
    • (1996) Dev Biol , vol.180 , pp. 242-257
    • Zhao, J.1    Bu, D.2    Lee, M.3    Slavkin, H.C.4    Hall, F.L.5    Warburton, D.6
  • 57
    • 0032519946 scopus 로고    scopus 로고
    • Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture
    • Zhao J, Lee M, Smith S, Warburton D. 1998. Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture. Dev Biol 194:182-195.
    • (1998) Dev Biol , vol.194 , pp. 182-195
    • Zhao, J.1    Lee, M.2    Smith, S.3    Warburton, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.