HNF-3/Forkhead homologue-4 influences lung morphogenesis and respiratory epithelial cell differentiation in vivo

Developmental Biology

Volumn 213, Issue 2, 1999, Pages 405-417

  Tichelaar, Jay W ^a   Lim, Lorena ^b   Costa, Robert H ^b   Whitsett, Jeffrey A ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

HFH 4; Lung morphogenesis; Respiratory epithelial cell differentiation; Winged helix

Indexed keywords

BETA TUBULIN; CELL MARKER; NUCLEAR FACTOR; SECRETORY PROTEIN; SURFACTANT PROTEIN B; SURFACTANT PROTEIN C; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CLARA CELL; CONTROLLED STUDY; EMBRYO; EPITHELIUM CELL; GENE EXPRESSION; LUNG DEVELOPMENT; LUNG PARENCHYMA; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; STEM CELL;

ANIMALIA; MUS MUSCULUS;

EID: 0033568043     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9380     Document Type: Article

References (36)

1. Adamson I. Y. R. Development of lung structure. Crystal R. G., West J. B., Weibel E. R., Barnes P. J. The Lung: Scientific Foundations. 1997;993-1001 Lippincot-Raven, Philadelphia.
2. Baatz J. E., Elledge B., Whitsett J. A. Surfactant protein SP-B induces ordering at the surface of model membrane bilayers. Biochemistry. 29:1990;6714-6720.
3. IV tubulin dimers from bovine brain. J. Biol. Chem. 267:1992;5625-5630.
4. Bohinski R. J., Di Lauro R., Whitsett J. A. The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis. Mol. Cell. Biol. 14:1994;5671-5681.
5. Bruno M. D., Bohinski R. J., Huelsman K. M., Whitsett J. A., Korfhagen T. R. Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1. J. Biol. Chem. 270:1995;6531-6536.
6. Chen J., Knowles H. J., Hebert J. L., Hackett B. P. Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J. Clin. Invest. 102:1998;1077-1082.
7. Cirillo L. A., McPherson C. E., Brossard P., Stevens K., Cherian S., Shim E. Y., Clark K. L., Burley S. K., Zaret K. S. Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. EMBO J. 17:1998;244-254.
8. Clark J. C., Wert S. E., Bachurski C. J., Stahlman M. T., Stripp B. R., Weaver T. E., Whitsett J. A. Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice. Proc. Natl. Acad. Sci. USA. 92:1995;7794-7798.
9. Clark K. L., Halay E. D., Lai E., Burley S. K. Co-crystal structure of the HNF-3/forkhead DNA-recognition motif resembles histone H5. Nature. 364:1993;412-420.
10. Clevidence D. E., Overdier D. G., Peterson R. S., Porcella A., Ye H., Paulson K. E., Costa R. H. Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter. Dev. Biol. 166:1994;195-209.
11. Duncan S. A., Navas M. A., Dufort D., Rossant J., Stoffel M. Regulation of a transcription factor network required for differentiation and metabolism. Science. 281:1998;692-695.
12. Fanucchi M. V., Murphy M. E., Buckpitt A. R., Philpot R. M., Plopper C. G. Pulmonary Cytochrome P450 monooxygenase and Clara cell differentiation in mice. Am. J. Respir. Cell. Mol. Biol. 17:1997;302-314.
13. Guazzi S., Price M., DeFelice M., Damante G., Mattei M.-G., DiLauro R. Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J. 9:1990;3631-3639.
14. Hackett B. P., Bingle C. D., Gitlin J. D. Mechanisms of gene expression and cell fate determination in the developing pulmonary epithelium. Annu. Rev. Physiol. 58:1996;51-71.
15. Hackett B. P., Brody S. L., Liang M., Zeitz I. D., Bruns L. A., Gitlin J. D. Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium. Proc. Natl. Acad. Sci. USA. 92:1995;4249-4253.
16. Ikeda K., Shaw-White J. R., Wert S. E., Whitsett J. A. Hepatocyte nuclear factor 3 activates transcription of thyroid transcription factor 1 in respiratory epithelial cells. Mol. Cell. Biol. 16:1996;3626-3636.
17. Jacob A., Budhiraja S., Qian X., Clevidence D., Costa R. H., Reichel R. R. Retinoid acid-mediated activation of HNF-3a during ES stem cell differentiation. Nucleic Acids Res. 22:1994;2126-2133.
18. Khoor A., Stahlman M. T., Gray M. E., Whitsett J. A. Temporal-spatial distribution of SP-B and SP-C proteins and mRNAs in developing respiratory epithelium of human lung. J. Histochem. Cytochem. 42:1994;1187-1199.
19. Kimura S., Hara Y., Pineau T., Fernandez-Salguero P., Fox C. H., Ward J. M., Gonzalez F. J. The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain and pituitary. Genes Dev. 10:1996;60-69.
20. Lim L., Zhou H., Costa R. H. The Winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in mouse embryo. Proc. Natl. Acad. Sci. USA. 94:1997;3094-3099.
21. Lin S., Akinbi H. T., Breslin J. S., Weaver T. E. Structural requirements for targeting of surfactant protein B (SP-B) to secretory granules in vitro and in vivo. J. Biol. Chem. 271:1996;19689-19695.
22. Motoyama J., Liu J., Mo R., Ding Q., Post M., Hui C.-c. Essential function of Gli2 and Gli3 in the formation of lung, trachea and esophagus. Nature Gen. 20:1998;1-4.
23. Murphy D. B., Seeman S., Wiese S., Kirschner R., Grzeschik K. H., Thies U. The human hepatocyte nuclear factor 3/forkhead gene FKHL13: Genomic structure and pattern of expression. Genomics. 40:1997;462-469.
24. Pelletier G. J., Brody S. L., Liapis H., White R. A., Hackett B. P. A human forkhead/winged-helix transcription factor expressed in developing pulmonary and renal epithelium. Am. J. Physiol. (Lung Cell Mol. Physiol.). 274:1998;L351-L359.
25. Post M. Tissue interactions. Crystal R. G., West J. B., Weibel E. R., Barnes P. J. The Lung: Scientific Foundations. 1997;1003-1011 Lippincot-Raven, Philadelphia.
26. IV is the major β-tubulin isotype in bovine cilia. Cell. Motil. Cytoskel. 25:1993;19-29.
27. Shim E. Y., Woodcock C., Zaret K. S. Nucleosome positioning by the winged helix transcription factor HNF3. Genes Dev. 12:1998;5-10.
28. Singh G., Singh J., Katyal S. J., Brown W. E., MacPherson J. A., Squeglia N. Identification, cellular localization, isolation and characterization of human Clara cell-specific 10 KD protein. J. Histochem. Cytochem. 36:1988;73-80.
29. Stahlman M. T., Gray M. E., Whitsett J. A. The ontogeny and distribution of surfactant protein B in human fetuses and newborns. J. Histochem. Cytochem. 40:1992;1471-1480.
30. Stahlman M. T., Gray M. E., Whitsett J. A. Expression of thyroid transcription factor-1(TTF-1) in fetal and neonatal human lung. J. Histochem. Cytochem. 44:1996;673-678.
31. Stahlman M. T., Gray M. E., Whitsett J. A. Temporal-spatial distribution of hepatocyte nuclear factor-3beta in developing human lung and other foregut derivatives. J. Histochem. Cytochem. 46:1998;955-962.
32. Tichelaar J. W., Wert S. E., Costa R. H., Kimura S., Whitsett J. A. HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung. J. Histochem. Cytochem. 47:1999;823.
33. Wert S., Glasser S., Korfhagen T., Whitsett J. Transcriptional elements from the human SP-C gene direct expression in the primordial respiratory epithelium of transgenic mice. Dev. Biol. 156:1993;426-443.
34. Zhou L., Dey C. R., Wert S. E., Whitsett J. A. Arrested lung morphogenesis in transgenic mice bearing an SP-C-TGF-β1 chimeric gene. Dev. Biol. 175:1996a;227-238.
35. Zhou L., Dey C. R., Wert S. E., Yan C., Costa R. H., Whitsett J. A. Hepatocyte nuclear factor-3β limits cellular diversity in the developing respiratory epithelium and alters lung morphogenesis in vivo. Dev. Dyn. 210:1997;305-314.
36. Zhou L., Lim L., Costa R. H., Whitsett J. A. Thyroid transcription factor-1, Hepatocyte nuclear factor-3β, surfactant protein B, C and Clara cell secretory protein in developing mouse lung. J. Histochem. Cytochem. 44:1996b;1183-1193.