Bmp4 and Fgf10 play opposing roles during lung bud morphogenesis

Development

Volumn 127, Issue 12, 2000, Pages 2695-2704

  Weaver, Molly ^b   Dunn, N Ray ^b,c   Hogan, Brigid L M ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Bmp4; Branching morphogenesis; Endoderm; Fgf10; In vitro culture; Lung; Respiratory epithelium; Tissue culture

Indexed keywords

BINDING PROTEIN; BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 10; MATRIGEL; NOGGIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CHEMOTAXIS; EMBRYO; EMBRYOLOGY; ENDODERM; GENE EXPRESSION REGULATION; LUNG; MESENCHYME; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL DIVISION; ENDODERM; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTORS; LUNG; MESODERM; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MORPHOGENESIS; ORGAN CULTURE TECHNIQUES; RESPIRATORY MUCOSA;

EID: 0033933136     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Alescio, T. and Cassini, A. (1962). Induction in vitro of tracheal buds by pulmonary mesenchyme grafted en tracheal epithelium. J. Exp. Zool. 150, 83-94.
2. Arman, E., Haffner-Krausz, R., Gorivodsky, M. and Lonai, P. (1999). Fgfr2 is required for limb outgrowth and lung-branching morphogenesis. Proc. Natl. Acad. Sci. USA 96, 11895-11899.
3. Beer, H. D., Florence, C., Dammeier, J., McGuire, L., Werner, S. and Duan, D. R. (1997). Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression. Oncogene 15, 2211-2218.
4. Bellusci, S., Henderson, R., Winnier, G., Oikawa, T. and Hogan, B. L. M. (1996). Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development 122, 1693-1702.
5. Bellusci, S., Furuta, Y., Rush, M. G., Henderson, R., Winnier, G. and Hogan, B. L. M. (1997a). Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development 124, 53-63.
6. Bellusci, S., Grindley, J., Emoto, H., Itoh, N. and Hogan, B. L. M. (1997b). Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124, 4867-4878.
7. Bitgood, M. J. and McMahon, A. P. (1995). Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 172, 126-138.
8. Burdine, R. D., Branda, C. S. and Stern, M. J. (1998). EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans. Development 125, 1083-1093.
9. Cardoso, W. V. (1995). Transcription factors and pattern formation in the developing lung. Am. J. Physiol. 269, L429-442.
10. Cardoso, W. V., Itoh, A., Nogawa, H., Mason, I. and Brody, J. S. (1997). FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium. Dev. Dyn. 208, 398-405.
11. Celli, G., LaRochelle, W. J., Mackem, S., Sharp, R. and Merlino, G. (1998). Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J. 17, 1642-1655.
12. De Moerlooze, L., Spencer-Dene, B., Revest, J., Hajihosseini, M., Rosewell, I. and Dickson, C. (2000). An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 127, 483-492.
13. Gumbiner, B. M. (1992). Epithelial morphogenesis. Cell 69, 385-387.
14. Hogan, B. L. M., Beddington, R., Costantini, F. and Lacy, E. (1994). Manipulating the Mouse Embryo. Cold Spring Harbor, NY: Cold Spring Harbor Press.
15. Hogan, B. L. M., Grindley, J., Bellusci, S., Dunn, N. R., Emoto, H. and Itoh, N. (1997). Branching morphogenesis of the lung: new models for a classical problem. Cold Spring Harb. Symp. Quant. Biol. 62, 249-256.
16. Hogan, B. L. M. (1999). Morphogenesis. Cell 96, 225-233.
17. Jung, H. S., Francis-West, P. H., Widelitz, R. B., Jiang, T. X., Ting-Berreth, S., Tickle, C., Wolpert, L. and Chuong, C. M. (1998). Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning. Dev. Biol. 196, 11-23.
18. Klambt, C., Glazer, L. and Shilo, B. Z. (1992). breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes Dev. 6, 1668-1678.
19. Lawson, K. A., Dunn, N. R., Roelen, B. A., Zeinstra, L. M., Davis, A. M., Wright, C. V., Korving, J. P. and Hogan, B. L. M. (1999). Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev. 13, 424-436.
20. Lebeche, D., Malpel, S. and Cardoso, W. V. (1999). Fibroblast growth factor interactions in the developing lung. Mech. Dev. 86, 125-136.
21. Li, S. and Muneoka, K. (1999). Cell migration and chick limb development: chemotactic action of FGF-4 and the AER. Dev. Biol. 211, 335-347.
22. Martin, G. R. (1998). The roles of FGFs in the early development of vertebrate limbs. Genes Der. 12, 1571-1586.
23. Metzger, R. J. and Krasnow, M. A. (1999). Genetic control of branching morphogenesis. Science 284, 1635-1639.
24. Min, H., Danilenko, D. M., Scully, S. A., Bolon, B., Ring, B. D., Tarpley, J. E., DeRose, M. and Simonet, W. S. (1998). Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev. 12, 3156-3161.
25. Montell, D. J. (1999). The genetics of cell migration in Drosophila melanogaster and Caenorhabditis elegans development. Development 126, 3035-3046.
26. Niswander, L. and Martin, G. R. (1993). FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361, 68-71.
27. Nogawa, H. and Ito, T. (1995). Branching morphogenesis of embryonic mouse lung epithelium in mesenchyme-free culture. Development 121, 1015-1022.
28. Nogawa, H., Morita, K. and Cardoso, W. V. (1998). Bud formation precedes the appearance of differential cell proliferation during branching morphogenesis of mouse lung epithelium in vitro. Dev. Dyn. 213, 228-235.
29. Noramly, S. and Morgan, B. A. (1998). BMPs mediate lateral inhibition at successive stages in feather tract development. Development 125, 3775-3787.
30. Park, W. Y., Miranda, B., Lebeche, D., Hashimoto, G. and Cardoso, W. V. (1998). FGF-10 is a chemotactic factor for distal epithelial buds during lung development. Dev. Biol. 201, 125-134.
31. Patel, K., Makarenkova, H. and Jung, H. S. (1999). The role of long range, local and direct signalling molecules during chick feather bud development involving the BMPs, follistatin and the Eph receptor tyrosine kinase Eph-A4. Mech. Dev. 86, 51-62.
32. Peters, K. G., Werner, S., Chen, G. and Williams, L. T. (1992). Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development 114, 233-243.
33. Peters, K., Werner, S., Liao, X., Wert, S., Whitsett, J. and Williams, L. (1994). Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J. 13, 3296-3301.
34. Pizette, S. and Niswander, L. (1999). BMPs negatively regulate structure and function of the limb apical ectodermal ridge. Development 126, 883-894.
35. Ramirez-Weber, F. A. and Kornberg, T. B. (1999). Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 97, 599-607.
36. Sekine, K., Ohuchi, H., Fujiwara, M., Yamasaki, M., Yoshizawa, T., Sato, T., Yagishita, N., Matsui, D., Koga, Y., Itoh, N. and Kato, S. (1999). Fgf10 is essential for limb and lung formation. Nat. Genet. 21, 138-141.
37. Shannon, J. M. (1994). Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme. Dev. Biol. 166, 600-6014.
38. Shannon, J. M., Nielsen, L. D., Gebb, S. A. and Randell, S. H. (1998). Mesenchyme specifies epithelial differentiation in reciprocal recombinants of embryonic lung and trachea. Dev. Dyn. 212, 482-494.
39. Sutherland, D., Samakovlis, C. and Krasnow, M. A. (1996). branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 87, 1091-1101.
40. Taderera, J. V. (1967). Control of lung differentiation in vitro. Dev. Biol. 16, 489-512.
41. Thesleff, I., Vaahtokari, A. and Partanen, A. M. (1995). Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs. Int. J. Dev. Biol. 39, 35-50.
42. Tickle, C. (1999). Morphogen gradients in vertebrate limb development. Semin. Cell Dev. Biol. 10, 345-351.
43. Vainio, S., Karavanova, I., Jowett, A. and Thesleff, I. (1993). Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75, 45-58.
44. Weaver, M., Yingling, J. M., Dunn, N. R., Bellusci, S, and Hogan, B. L. (1999). Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development. Development 126, 4005-4015.
45. Wessels, N. K. (1970). Mammalian lung development: interactions in formation and morphogenesis of tracheal buds. J. Exp. Zool. 175, 455-466.
46. Winnier, G., Blessing, M., Labosky, P. A. and Hogan, B. L. M. (1995). Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9, 2105-16.
47. Xu, X., Weinstein, M., Li, C., Naski, M., Cohen, R. I., Ornitz, D. M., Leder, P. and Deng, C. (1998). Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125, 753-65.
48. Zimmerman, L. B., De Jesus-Escobar, J. M. and Harland, R. M. (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606.