Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos

EMBO Journal

Volumn 16, Issue 14, 1997, Pages 4163-4173

  Fujii, Hideta ^a,b   Sato, Takashi ^c   Kaneko, Sinya ^a   Gotoh, Osamu ^d   Fujii Kuriyama, Yoshiaki ^e   Osawa, Kanju ^c   Kato, Shigeaki ^c,f   Hamada, Hiroshi ^a,b  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^d SAITAMA MEDICAL UNIVERSITY   (Japan)

^e TOHOKU UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cytochrome P450; Embryogenesis; Metabolism; Retinoic acid

Indexed keywords

CYTOCHROME P450 ISOENZYME; RETINAL; RETINOIC ACID; RETINOL;

ANIMAL TISSUE; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE EXPRESSION; METABOLIC ACTIVATION; MOUSE; NEURAL CREST CELL; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; VITAMIN METABOLISM;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; CELL LINE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU HYBRIDIZATION; MICE; MICROSCOPY, PHASE-CONTRAST; MOLECULAR SEQUENCE DATA; OXYGENASES; RECEPTORS, RETINOIC ACID; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TRANSFECTION; TRETINOIN;

ANIMALIA; MAMMALIA; VERTEBRATA;

EID: 0030872361     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.14.4163     Document Type: Article

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