CD40L pathway blockade as an approach to immunotherapy

Advances in Experimental Medicine and Biology

Volumn 489, Issue , 2001, Pages 135-152

  Burkly, Linda C ^a  

^a BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 39; CD40 ANTIGEN; CD40 LIGAND; CELL ADHESION MOLECULE; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY;

ALLOTRANSPLANTATION; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BACTERIAL INFECTION; CELL ACTIVATION; CELL INTERACTION; CELL STIMULATION; CONFERENCE PAPER; FIBROSIS; HEMOPHILIA; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; VASCULAR DISEASE; VIRUS INFECTION; WOUND HEALING; ALLERGIC ENCEPHALOMYELITIS; ANIMAL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTERIOSCLEROSIS; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL COMMUNICATION; CHEMOTAXIS; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; GRAFT REJECTION; HELPER CELL; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOLOGY; LUNG FIBROSIS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; MACACA; METHODOLOGY; MOUSE; MULTIGENE FAMILY; PHYSIOLOGY; REVIEW; STROMA CELL;

BACTERIA (MICROORGANISMS);

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD40; ARTERIOSCLEROSIS; AUTOIMMUNE DISEASES; CD40 LIGAND; CELL ADHESION MOLECULES; CELL COMMUNICATION; CHEMOTAXIS; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION REGULATION; GRAFT REJECTION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COOPERATION; MACACA FASCICULARIS; MICE; MODELS, IMMUNOLOGICAL; MULTIGENE FAMILY; PULMONARY FIBROSIS; RECEPTORS, ANTIGEN, T-CELL; STROMAL CELLS; T-LYMPHOCYTES, HELPER-INDUCER; VIRUS DISEASES;

EID: 0035036587     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: 10.1007/978-1-4615-1277-6_12     Document Type: Article

References (144)

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83. Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation
84. Cutting edge: Sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease
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125. Blockade of CD40L/CD40 costimulatory pathway in a DST presensitization model of islet allograft leads to a state of Allo-Ag specific tolerance and permits subsequent engraftment of donor strain islet or heart allografts
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132. CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response
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