T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism: Implications for tubule formation

American Journal of Pathology

Volumn 154, Issue 1, 1999, Pages 229-238

  Mach, François ^a   Schönbeck, Uwe ^a   Fabunmi, Rosalind P ^a   Murphy, Curran ^a   Atkinson, Elizabeth ^a   Bonnefoy, Jean Yves ^b   Graber, Pierre ^b   Libby, Peter ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; COLLAGENASE; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; METALLOPROTEINASE; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ATHEROGENESIS; CELL INFILTRATION; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME RELEASE; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NEOVASCULARIZATION (PATHOLOGY); PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0344699318     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65269-8     Document Type: Article

References (51)

1. Panayi GS, Lanchbury JS, Kingsley GH: The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992, 35:729-735
2. Hale HP, Martin ME, McCollum DE, Nunley JA, Springer TA, Singer KH, Hayes BF: Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. Arthritis Rheum 1989, 32:22-30
3. Weidner N, Semple JP, Welche WR, Folkman J: Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 1991, 324:1-8
4. Vartanian RK, Weidner N: Correlation of intramural endothelial cell proliferation with microvessels density (tumor angiogenesis) and tumor cell proliferation in breast carcinoma. Am J Pathol 1994, 144: 1188-1194
5. Barger AC, Beewkes R III, Lainey LL, Silverman KJ: Vasa vasorum and neovascularization of human coronary arteries: a possible role in the pathophysiology of atherosclerosis. N Engl J Med 1984, 310:175-177
6. Zhang Y, Cliff WJ, Schoefl GI, Higgings G: Immunohistochemical study of intimal microvessels in coronary atherosclerosis. Am J Pathol 1993, 143:164-172
7. Krzesicki RF, Fleming WE, Winterrowd GE, Hatfield CA, Sanders ME, Chin JE: T lymphocyte adhesion to human synovial fibroblasts: role of cytokines and the interaction between intercellular adhesion molecule-1 and CD11a/CD18. Arthritis Rheum 1991, 34:1245-1253
8. Watanabe M, McCormick KL, Volker K, Ortaldo JR, Wigginton JM, Brunda MJ, Wiltrout RH, Fogler WE: Regulation of local host-mediated anti-tumor mechanisms by cytokines: direct and indirect effects on leukocytes recruitment and angiogenesis. Am J Pathol 1997, 150: 1869-1880
9. O'Brien KD, McDonald TO, Chait A, Allen MD, Alpers CE: Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. Circulation 1996, 93:672-682
10. Ingber D: Extracellular matrix and cell shape: potential control points for inhibition of angiogenesis. J Cell Biochem 1991, 47:236-241
11. Emonard H, Grimaud JA: Matrix metalloproteinases: a review. Cell Mol Biol 1990, 36:131-153
12. Manuel D, Murray C, Risau W, Clauss M: 1996. Tumor necrosis: factors and principles. Immunol Today 1996, 17:254-256
13. Moscatelli D, Rifkin DB: Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis. Biochim Biophys Acta 1988, 948:67-85
14. Woessner JF Jr: Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J 1991, 5:2145-2154
15. Matrisian LM: Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet 1990, 6:121-125
16. Stetler-Stevenson WG: The type IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev 1990, 9:289-303
17. Hanemaaijer R, Koolwijk P, le Clercq L, de Vree WJA, van Hinsbergh WM: Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Biochem J 1993, 296:803-809
18. Bevilacqua MP: Endothelial-leukocyte adhesion molecules. Annu Rev Immunol 1993, 11:767-804
19. Springer TA: Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994, 76:301-314
20. Karmann K, Hughes CCW, Schechner J, Fanslow WC, Pober JS: CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. Proc Natl Acad Sci USA 1995, 92:4342-4346
21. Yellin MJ, Brett J, Baum D, Matsushima A, Szabolcs M, Stern D, Chess L: Functional interaction of T cells with endothelial cells: the role of CD40L-CD40-mediated signals. J Exp Med 1995, 182:1857-1864
22. Hollenbaugh D, Mischel-Petty N, Edwards CP, Simons JC, Denfeld RW, Kiener PA, Aruffo A: Expression of functional CD40 by vascular endothelial cells. J Exp Med 1995, 182:33-40
23. Laman JD, Claassen E, Noelle RJ: Functions of CD40 and its ligand, gp39. Crit Rev Immunol 1996, 16:59-108
24. Foy TM, Aruffo A, Bajorath J, Buhlmann JE, Noelle RJ: Immune regulation by CD40 and its ligand gp39. Annu Rev Immunol 1996, 14:591-617
25. Rathmell JC, Townsend SE, Xu JC, Flavell RA, Goodnow CC: Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 1996, 87:319-329
26. Lederman S, Yellin MJ, Krichevsky A, Belko J, Lee JJ, Chess L: Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help). J Exp Med 1992, 175:1091-1101
27. Gerritse K, Laman J, Noelle R, Aruffo A, Ledbetter J, Boersma W, Classen E: CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis. Proc Natl Acad Sci USA 1996, 93:2499-2504
28. Francisco JA, Gilliland LK, Stebbins MR, Norris NA, Ledbetter JA, Siagall CB: Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen. Cancer Res 1995, 55:3099-3104
29. Van den Oord JJ, Maos A, Stas M, Nuyts J, Battocchio S, Kastan A, Garmyn M, de Wever I, de Wolf-Peeters C: CD40 is a prognostic marker in primary cutaneous malignant melanoma. Am J Pathol 1996, 149:1953-1961
30. Yellin MJ, D'Agati V, Parkinson G, Soh-Yung Han A, Szema A, Baum D, Estes D, Szabolcs M, Chess L: Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritis. Arthritis Rheum 1997, 40:124-134
31. Yellin MJ, Szabolcs M, Han A, Michler R, Cannon PJ, Chess L: CD40L+CD4+ T cells and CD40+ target cells are present in atherosclerosis and transplant coronary artery disease. Circulation 1996, 94:4a
32. Mach F, Schönbeck U, Sukhova GK, Bourcier T, Bonnefoy JY, Pober JS, Libby P: Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis. Proc Natl Acad Sci USA 1997, 94:1931-1936
33. Mazzei GJ, Edgerton MD, Losberger C, Lecoanet-Henchoz SP, Durandy A, Gauchat JF, Bernard A, Allet B, Bonnefoy JY: Human native soluble CD40L is a biologically active trimer, processed inside microsomes. J Biol Chem 1995, 270:7025-7028
34. Gimbrone MA Jr, Cotran RS, Folkman J: Human vascular endothelial cells in culture: growth and DNA synthesis. J Cell Biol 1974, 60:673-684
35. Malik N, Greenfield BW, Wahl AF, Kiener PA: Activation of human monocytes through CD40 induces matrix metalloproteinases. J Immunol 1996, 156:3952-3960
36. Herron GS, Werb Z, Dwyer K, Banda MJ: Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and stromelysin exceeds expression of proteolytic activity. J Biol Chem 1986, 2810-2813
37. Montesano R, Pepper MS, Orci L: Phorbol ester induces cultured endothelial cells to invade a fibrin matrix in the presence of fibrinolytic inhibitors. J Cell Physiol 1987, 132:509-516
38. Montesano R, Vassalli JD, Baird A, Guillemin R, Orci L: Basic fibroblast growth factor induces angiogenesis in vitro. Proc Natl Acad Sci USA 1986, 83:7297-7301
39. Tanaka H, Sukhova GK, Libby P: Interaction of the allogeneic state and hypercholesterolemia in arterial lesion formation in experimental cardiac allografts. Arterioscler Thromb 1994, 14:734-745
40. Hansson GK, Joansson L, Lojsthed B, Stemme S, Kocher O, Gabbiani G: 1988. Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. Atherosclerosis 1988, 72:135-141
41. Zhou X, Stemme S, Hansson GK: Evidence for a local immune response in atherosclerosis. Am J Pathol 1996, 149:359-366
42. Libby P, Li H, Cybulsky MI: Adhesion molecules in recruitment of mononuclear cells to the arterial intima. Atherosclerosis X. Edited by Davignon J, Woodford FP, Sniderman A. Amsterdam, Elsevier, 1995, pp 582-585
43. Libby P: Pathogenesis of atherosclerosis: cellular interactions. Vascular Medicine, ed 2. Edited by Loscalzo JM, Creager M, Dzau V, Boston, Little, Brown & Co, 1995, pp 297-307
44. Freeman MR, Schenck FX, Gagnon ML, Corless C, Soker S, Niknejad K, Poeples GE, Klagsbrun M: Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis Cancer Res 1995, 55:4140-4145
45. Unemori EN, Ferrara N, Bauer EA, Amento EP: Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol 1992, 153:557-562
46. Laman JD, de Smet BJ, Schoneveld A, van Meurs M: CD40-CD40L interactions in atherosclerosis. Immunol Today 1997, 18:272-276
47. Schönbeck U, Mach F, Sukhova GK, Murphy C, Bonnefoy JY, Fabunmi RP, Libby P: Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture? Circ Res 1997, 81:448-454
48. Mach F, Schönbeck U, Bonnefoy JY, Pober JS, Libby P: Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. Circulation 1997, 96:396-399
49. Galis ZS, Sukhova GK, Lark MW, Libby P: Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin invest 1994, 94: 2493-2503
50. Romanic AM, Madri JA. The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells in VCAM-1 dependent. J Biol Chem 1994, 125:1165-1178
51. Schönbeck U, Mach F, Bonneloy JY, Loppnow H, Flad HD, Libby P: Ligation of CD40 activates interleukin 1β-converting enzyme activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1β. J Biol Chem 1997, 272:19569-19574